Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   CSC49_RS12050 Genome accession   NZ_CP029084
Coordinates   2360224..2362425 (-) Length   733 a.a.
NCBI ID   WP_001622275.1    Uniprot ID   A0A0U1MM33
Organism   Staphylococcus aureus strain AR464     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2355224..2367425
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSC49_RS12035 (CSC49_2246) lepA 2356728..2358551 (-) 1824 WP_043859323.1 translation elongation factor 4 -
  CSC49_RS12040 (CSC49_2247) rpsT 2358897..2359148 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  CSC49_RS12045 (CSC49_2248) holA 2359193..2360167 (-) 975 WP_001282573.1 DNA polymerase III subunit delta -
  CSC49_RS12050 (CSC49_2249) comEC 2360224..2362425 (-) 2202 WP_001622275.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  CSC49_RS12055 (CSC49_2250) - 2362430..2362891 (-) 462 WP_000439693.1 ComE operon protein 2 -
  CSC49_RS12060 (CSC49_2251) comEA 2362983..2363669 (-) 687 WP_072468915.1 ComEA family DNA-binding protein Machinery gene
  CSC49_RS12065 (CSC49_2252) - 2363709..2364425 (-) 717 WP_000084840.1 class I SAM-dependent methyltransferase -
  CSC49_RS12070 (CSC49_2253) rsfS 2364428..2364781 (-) 354 WP_001088020.1 ribosome silencing factor -
  CSC49_RS12075 (CSC49_2254) yqeK 2364782..2365366 (-) 585 WP_001017837.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  CSC49_RS12080 (CSC49_2255) nadD 2365356..2365925 (-) 570 WP_064135564.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  CSC49_RS12085 (CSC49_2256) yhbY 2365928..2366218 (-) 291 WP_000955234.1 ribosome assembly RNA-binding protein YhbY -
  CSC49_RS12090 (CSC49_2257) aroE 2366222..2367028 (-) 807 WP_042744294.1 shikimate dehydrogenase -

Sequence

Protein


Download         Length: 733 a.a.        Molecular weight: 85048.20 Da        Isoelectric Point: 10.0564

>NTDB_id=290227 CSC49_RS12050 WP_001622275.1 2360224..2362425(-) (comEC) [Staphylococcus aureus strain AR464]
MLYVALSMIVGVLWNSSKVLSTFLFILLLYIAYRKNKIVYAPISLFLIIFSSWYLHYSQQAIFNYINYIERNSQFNERAQ
VIQIQRQGSDTYKGRLSLKNEIYPFFLTNKKNFDLKKIESRNCIVKGQFKVNDNKFVTLKLQSIVVQSCLESNRSNLIEK
HKQFIMNRIYDSGIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAIVLLIYQPLKRLNLPLFVIKGIT
IIVLALFAQYTNYAPSAVRAIIMTTLVLLITKQIKIKGIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQ
QLSKLQSLFIITFIAQLASFIVAIPNFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTPLNYLVDLSFNFH
DWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRKYILVTFWTIIILTLLITLPTNSHHKITMLNVGQGDSI
LYEGGKNQNVLIDTGGKVFDDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGEVEYIISHIKIKHIVIYNKG
YSSNTLMLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNEYLLL
KKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNL
KVDSNSYRNASGL

Nucleotide


Download         Length: 2202 bp        

>NTDB_id=290227 CSC49_RS12050 WP_001622275.1 2360224..2362425(-) (comEC) [Staphylococcus aureus strain AR464]
TTGCTGTATGTCGCGTTATCAATGATTGTAGGAGTACTTTGGAATTCTAGCAAAGTGCTCTCTACATTTCTTTTCATTTT
ACTTTTGTATATTGCTTATCGTAAAAATAAAATCGTTTATGCCCCTATTTCTCTCTTTTTAATCATTTTCTCCTCATGGT
ATTTACATTATTCACAACAAGCAATATTTAATTATATCAATTATATTGAACGTAATTCTCAGTTTAATGAGCGTGCTCAA
GTAATCCAAATTCAACGTCAAGGTAGTGACACATATAAAGGTAGATTAAGTTTAAAAAATGAAATATATCCTTTCTTTTT
AACAAATAAAAAGAATTTTGATTTAAAGAAAATTGAAAGTCGTAATTGTATTGTTAAAGGACAATTCAAAGTTAATGACA
ATAAGTTTGTAACTCTTAAATTACAAAGTATAGTTGTACAAAGCTGCCTAGAATCGAACCGGTCTAATTTAATTGAGAAA
CATAAACAGTTTATAATGAATCGAATTTATGATTCGGGTATTAAGTTTCCGGATCGTATTATGGCATTGATTACTGGTGA
CGTAAAAGAAATTAATGAGCAATTTAAGGAACGTGTTAAAGAAATAGGTATATATCATTTGCTGGCAGTTAGTGGCTCGC
ATATAGCTGCAATTGTATTATTAATTTACCAACCTTTAAAACGATTAAATTTACCTTTATTTGTCATTAAAGGAATTACA
ATCATTGTATTAGCTTTATTTGCTCAATACACAAATTATGCACCTAGTGCTGTAAGAGCTATAATAATGACAACGCTTGT
ACTGCTTATTACTAAGCAAATTAAAATAAAGGGTATTCAACTATTAGCATTTGCATTTATAATTATGTTTATTTTAAATC
CGCTAGTTGTTTATGATATTGGATTTCAATTTTCATTCATCATTTCATTTTTTATTATGCTGCTTTTCCCTTTTTTACAG
CAATTGTCAAAGTTACAATCATTATTCATAATTACGTTTATTGCACAATTAGCTTCATTTATCGTTGCCATTCCAAACTT
TCATCAACTTCAATGGGTGGGATTTTTATCTAATTTGATTTTTGTACCGTACTATTCGATTATATTGTTTCCGCTATCTA
TTTTATTCTTTATTACAAGTCATTTTATTGTGGGATTAACGCCGCTAAATTACTTGGTTGACCTAAGTTTTAATTTTCAT
GACTGGTTACTAGACTTATTCACAAGAATCAAGCAATCACATTTTTCTGTTCCCAAGTTTAATGATTGGATATTTATAAT
ATTTATAATTTCTGTTTATTACATATTTTGGTTATTGGCTAAACGTAAATATATATTGGTTACGTTTTGGACTATAATTA
TTCTGACATTATTAATAACGCTTCCAACAAATTCACATCACAAAATTACAATGTTAAATGTGGGACAAGGAGACAGTATT
TTATATGAAGGTGGTAAGAACCAAAATGTATTGATTGATACAGGTGGGAAAGTGTTTGATGATACTAAACAACCTAGTTA
TTCAATTTCTAAATATCATATTTTACCAACGTTAAATGAAAGAGGGATAAATGAATTAGAGTACCTAATTTTAACACATC
CACACAATGACCATATTGGCGAAGTGGAATATATTATTAGTCATATTAAAATTAAACATATAGTGATATACAATAAAGGA
TATAGTAGTAATACATTGATGTTATTATCGAAATTAAGCCATAAGTACAACATTAAACTTATGGATGTAAGACAAGTTAG
TAGTTTTAAACTTGGAGATAGTAGTTTTCTATTTTTTGATAGTTTTATTCCAAATAGCCGAGATAAAAATGAATATTCGA
TTATTACTATGATTACATATCAAAATAAAAAAGTTTTATTAATGGGCGATGCTAGTAAAAATAATGAATATTTACTACTA
AAAAAATATAACTTGCCGGAGATTGATATTTTAAAAGTAGGACATCATGGGAGCAAGACAAGTAGTTCTAAAGAATTTAT
AGAGATGATTAAGCCTAAAATAAGTTTGATTTCTTCTGGGAAGAACAATATGTATCATCTTCCTAACATAGAAGTTGTTA
AACGATTGCAAAGGATTCGCAGTCGCATTTACAATAGTCAACAAAACGGTCAAGTTACAATTGACTTAGATGATAATTTA
AAAGTTGATTCAAACTCTTATAGAAATGCAAGTGGTTTATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(474-679)

Competence protein (Competence)

(183-441)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0U1MM33

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Staphylococcus aureus N315

98.636

100

0.986
  comEC Staphylococcus aureus MW2

98.499

100

0.985

Multiple sequence alignment