Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   CGQ00_RS08995 Genome accession   NZ_CP022908
Coordinates   1728741..1729427 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain 545     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1723741..1734427
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGQ00_RS08975 (CGQ00_01661) rpsT 1724655..1724906 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  CGQ00_RS08980 (CGQ00_01662) holA 1724951..1725925 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  CGQ00_RS08985 (CGQ00_01663) comEC 1725982..1728183 (-) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  CGQ00_RS08990 (CGQ00_01664) - 1728188..1728649 (-) 462 WP_000439693.1 ComE operon protein 2 -
  CGQ00_RS08995 (CGQ00_01665) comEA 1728741..1729427 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  CGQ00_RS09000 (CGQ00_01666) - 1729467..1730183 (-) 717 WP_115276646.1 class I SAM-dependent methyltransferase -
  CGQ00_RS09005 (CGQ00_01667) rsfS 1730186..1730539 (-) 354 WP_001088022.1 ribosome silencing factor -
  CGQ00_RS09010 (CGQ00_01668) yqeK 1730540..1731124 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  CGQ00_RS09015 (CGQ00_01669) nadD 1731114..1731683 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  CGQ00_RS09020 (CGQ00_01670) yhbY 1731686..1731976 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  CGQ00_RS09025 (CGQ00_01671) aroE 1731980..1732786 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  CGQ00_RS09030 (CGQ00_01672) yqeH 1732800..1733900 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=243330 CGQ00_RS08995 WP_001792568.1 1728741..1729427(-) (comEA) [Staphylococcus aureus strain 545]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=243330 CGQ00_RS08995 WP_001792568.1 1728741..1729427(-) (comEA) [Staphylococcus aureus strain 545]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969

Multiple sequence alignment