Detailed information NTG0226982

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: B0B39_RS13685
• Genome accession: NZ_CP020894
• Coordinates: 3098813..3101035 (+)
• Length: 740 a.a.
• NCBI ID: WP_003635596.1
• Uniprot ID: D3HKP4
• Organism: Legionella longbeachae strain F1157CHC
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3093813..3106035

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B0B39_RS13660 (B0B39_06925)	-	3094054..3094692 (-)	639	WP_003635606.1	hypothetical protein	-
B0B39_RS13665 (B0B39_06930)	-	3094934..3095959 (-)	1026	WP_003635604.1	spermidine/putrescine ABC transporter substrate-binding protein	-
B0B39_RS13670 (B0B39_06935)	-	3095956..3096723 (-)	768	WP_003635601.1	ABC transporter permease subunit	-
B0B39_RS13675 (B0B39_06940)	-	3096720..3097544 (-)	825	WP_003635599.1	ABC transporter permease subunit	-
B0B39_RS13680 (B0B39_06945)	potA	3097534..3098628 (-)	1095	WP_003635598.1	spermidine/putrescine ABC transporter ATP-binding protein PotA	-
B0B39_RS13685 (B0B39_06950)	comEC	3098813..3101035 (+)	2223	WP_003635596.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
B0B39_RS13690 (B0B39_06955)	-	3101145..3102194 (+)	1050	WP_003635594.1	trifunctional transcriptional activator/DNA repair protein Ada/methylated-DNA--[protein]-cysteine S-methyltransferase	-
B0B39_RS13695 (B0B39_06960)	-	3102551..3102778 (-)	228	WP_172622913.1	hypothetical protein	-
B0B39_RS13700 (B0B39_06965)	-	3103204..3104019 (-)	816	WP_003635585.1	mechanosensitive ion channel family protein	-
B0B39_RS13705 (B0B39_06970)	-	3104342..3104686 (-)	345	WP_085662572.1	hypothetical protein	-
B0B39_RS13710 (B0B39_06975)	-	3105021..3105407 (+)	387	WP_003635579.1	group III truncated hemoglobin	-
B0B39_RS18835	cydP	3105401..3105571 (+)	171	WP_003635577.1	cytochrome oxidase putative small subunit CydP	-

Sequence

Protein

• Length: 740 a.a.
• Molecular weight: 83609.84 Da
• Isoelectric Point: 9.6797

>NTDB_id=226982 B0B39_RS13685 WP_003635596.1 3098813..3101035(+) (comEC) [Legionella longbeachae strain F1157CHC]
MEIFCFFIGILYRYTLHGLLPILILFIFFIIPRYANILFFLLGIFIATVHQSQNLPKGLPDVEVIPQVSIQGTIASIPLQ
SPSKTLFLLALEQYDNHPAQGIIQLSWYNKAPKIHVGQRWKFKVKLKKPRNYLNPGSMDYVRSLATRHILWTGYIHSRGN
KQLPKVPSSFNWLELREQLSEQLGLLAPDQKTAGIVEALALNITTHIDQKSWDLFRRTGTTHLFGISGEHIALISGIIYW
LLRWIWTRSSRLCLRIPAPHIASMGGLLAASGYAFLAGFAPPVQRALIGCFFYTLYSLGYQRFTPWQVWRYALCGVLLIE
PHAVFMQGFYFSFLAVACLLLTQQRWRLKGYKASLALQLSCLIGLMPLTLYWYAYGSINGFIANLFAIPLVGLLIVPLSL
MTMTVSSLSIAKILMKAVSLLITLLFKGLSLSEYLAALNINCPIYSIELALVLIGALLMWVLLPTKPFQWIAMLWLLLPF
FPPRTIIQAGEAKIDVLDVGQGLAVAIRTQHHVLLYDTGDRFFQGNDLGKMVILPYLNTLGIKKIDTIVVSHPDKDHLGG
LKSLEKEIPVERLLVNEPHFYHRGLKCHDYPPWQWDGVSFRFLPIKIPLRGKNNSSCILQIETHAGRMLLAGDIEKIAED
YLVQTYGNILESDVLLVPHHGSKTSSSYRFLLEVAPLYAIASLGFDNRFHFPHDKTLANMKKLNIPFYRTDTCGMVQITL
PAQGALTHPTCFSGQRLQPV

Nucleotide

• Length: 2223 bp

>NTDB_id=226982 B0B39_RS13685 WP_003635596.1 3098813..3101035(+) (comEC) [Legionella longbeachae strain F1157CHC]
ATGGAAATTTTTTGCTTTTTTATAGGCATATTGTATCGATATACCTTACACGGATTATTGCCTATACTTATTTTATTTAT
TTTTTTCATTATTCCCAGGTATGCGAATATCCTGTTTTTTCTTTTAGGCATCTTCATCGCGACTGTGCACCAATCTCAAA
ATTTACCAAAAGGATTACCCGATGTTGAAGTAATACCCCAAGTCAGCATCCAAGGAACAATTGCATCTATTCCGCTCCAA
AGTCCATCTAAGACACTCTTTTTATTGGCTTTAGAACAATACGACAATCATCCAGCACAAGGGATAATACAATTATCATG
GTATAACAAAGCCCCCAAAATCCATGTAGGGCAACGATGGAAATTTAAAGTGAAATTGAAAAAGCCAAGAAATTATCTAA
ATCCAGGGAGTATGGATTATGTACGTTCACTCGCAACACGCCATATATTGTGGACTGGATATATTCATTCTAGAGGAAAT
AAGCAACTCCCAAAAGTCCCCTCATCTTTCAATTGGCTAGAACTAAGGGAACAATTAAGCGAGCAACTCGGCTTGTTGGC
ACCTGATCAAAAAACCGCTGGAATTGTAGAGGCTTTAGCTTTAAATATAACAACCCATATTGACCAGAAAAGCTGGGATT
TGTTTAGACGTACTGGCACAACCCATTTATTTGGTATTTCAGGTGAACATATCGCCTTAATTTCAGGTATTATTTATTGG
TTACTCCGTTGGATATGGACTCGAAGCTCTCGTCTTTGCTTACGCATTCCAGCCCCTCATATTGCAAGTATGGGTGGCCT
TTTGGCTGCATCAGGATATGCGTTTTTAGCAGGTTTTGCACCTCCTGTCCAAAGGGCACTTATCGGATGTTTTTTTTATA
CCCTTTATAGCTTGGGCTACCAGCGTTTTACTCCATGGCAAGTATGGCGCTATGCTCTATGTGGTGTCTTATTGATTGAA
CCACATGCCGTATTTATGCAAGGATTCTATTTTTCTTTTCTTGCAGTAGCATGCTTGCTCTTAACACAACAACGCTGGCG
TTTAAAAGGATATAAAGCCTCTTTAGCCCTACAGTTAAGCTGTTTAATTGGGTTAATGCCCCTAACCTTATATTGGTATG
CTTATGGCTCAATTAATGGATTTATTGCAAACCTTTTCGCTATACCTTTGGTGGGATTACTCATTGTTCCGTTGTCATTA
ATGACAATGACGGTCAGCTCTTTAAGCATTGCAAAGATACTAATGAAGGCCGTTTCTTTACTCATTACCCTATTGTTTAA
AGGGCTATCCTTGTCAGAATATTTAGCTGCTCTAAATATTAATTGCCCCATTTATTCTATAGAACTGGCTCTTGTTCTAA
TTGGAGCTTTATTGATGTGGGTTTTACTACCCACTAAACCTTTTCAATGGATCGCGATGCTTTGGTTATTGCTCCCGTTT
TTTCCACCGCGAACAATCATTCAAGCAGGCGAAGCCAAAATAGATGTTTTGGACGTAGGGCAAGGCTTGGCTGTTGCGAT
TCGAACGCAACACCATGTATTGCTTTATGATACAGGAGATCGTTTCTTTCAAGGAAATGATTTAGGGAAAATGGTTATTT
TGCCTTATCTTAACACTTTGGGTATCAAAAAAATTGATACCATAGTTGTGAGCCATCCTGATAAAGATCATCTTGGAGGA
CTTAAATCACTGGAAAAAGAAATACCAGTAGAGAGGCTATTAGTCAATGAGCCTCATTTCTATCATCGTGGTTTAAAATG
TCATGATTATCCACCATGGCAATGGGACGGTGTTTCGTTCCGTTTTCTGCCAATAAAAATTCCCCTTAGAGGAAAAAACA
ACAGTTCTTGCATTTTACAAATAGAAACACATGCAGGACGGATGCTCTTAGCTGGCGATATTGAAAAAATAGCTGAAGAT
TATCTGGTGCAGACTTATGGCAATATTCTTGAATCAGATGTGCTGCTTGTTCCTCATCATGGCAGTAAAACTTCATCATC
CTACAGATTCTTATTAGAAGTTGCTCCGCTCTATGCTATAGCCTCCCTGGGCTTTGATAATCGCTTTCACTTTCCCCATG
ACAAGACTTTAGCAAACATGAAAAAACTGAATATCCCTTTTTACAGAACAGATACTTGTGGCATGGTACAGATTACTTTG
CCTGCCCAAGGAGCACTCACTCATCCCACTTGCTTTAGTGGACAGAGGTTACAACCCGTGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (201-465)

• Metallo-beta-lactamase superfamily (Lactamase_B) (498-676)

• Domain of unknown function (DUF4131) (DUF4131) (16-157)

3D structure

• AlphaFold DB: D3HKP4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Legionella pneumophila strain Lp02	64.305	99.189	0.638
comEC	Legionella pneumophila strain ERS1305867	63.81	99.324	0.634