Detailed information NTG0221707

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FORC59_RS09700
• Genome accession: NZ_CP020354
• Coordinates: 1910007..1911050 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FORC59
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1905007..1916050

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FORC59_RS09670 (FORC59_1762)	-	1905429..1906685 (-)	1257	WP_001789555.1	aminopeptidase	-
FORC59_RS09675 (FORC59_1763)	-	1906688..1906888 (-)	201	WP_000180460.1	DUF1128 family protein	-
FORC59_RS09680 (FORC59_1764)	-	1907035..1907499 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
FORC59_RS09685 (FORC59_1765)	-	1907506..1907781 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
FORC59_RS09690 (FORC59_1766)	-	1908059..1909276 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
FORC59_RS09695 (FORC59_1767)	vraR	1909388..1910017 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
FORC59_RS09700 (FORC59_1768)	vraS	1910007..1911050 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
FORC59_RS09705 (FORC59_1769)	liaF	1911047..1911748 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
FORC59_RS09710 (FORC59_1770)	-	1911763..1912149 (-)	387	WP_001110179.1	hypothetical protein	-
FORC59_RS09715 (FORC59_1771)	map	1912366..1913124 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
FORC59_RS09725 (FORC59_1773)	-	1913714..1914700 (+)	987	WP_000999713.1	FUSC family protein	-
FORC59_RS09735 (FORC59_1774)	-	1915131..1915544 (-)	414	WP_001566709.1	hypothetical protein	-
FORC59_RS09740	-	1915573..1915684 (-)	112	Protein_1803	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=221707 FORC59_RS09700 WP_001017131.1 1910007..1911050(-) (vraS) [Staphylococcus aureus strain FORC59]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=221707 FORC59_RS09700 WP_001017131.1 1910007..1911050(-) (vraS) [Staphylococcus aureus strain FORC59]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1