Detailed information NTG0216722

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: BZK08_RS13985
• Genome accession: NZ_CP019594
• Coordinates: 2688263..2689150 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain GD1539
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2683263..2694150

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BZK08_RS13950 (BZK08_14290)	-	2683272..2683364 (+)	93	WP_031774855.1	hypothetical protein	-
BZK08_RS13955 (BZK08_14295)	-	2683472..2683969 (-)	498	WP_001065267.1	glutathione peroxidase	-
BZK08_RS13960 (BZK08_14300)	-	2683979..2684239 (-)	261	WP_014937088.1	hypothetical protein	-
BZK08_RS13970 (BZK08_14310)	-	2684621..2684734 (-)	114	WP_014937089.1	hypothetical protein	-
BZK08_RS13975 (BZK08_14315)	-	2685403..2687403 (-)	2001	WP_000776741.1	ABC transporter permease	-
BZK08_RS13980 (BZK08_14320)	-	2687400..2688155 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
BZK08_RS13985 (BZK08_14325)	braS	2688263..2689150 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
BZK08_RS13990 (BZK08_14330)	braR	2689161..2689826 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
BZK08_RS13995 (BZK08_14335)	-	2689852..2690052 (-)	201	WP_000604731.1	hypothetical protein	-
BZK08_RS14000 (BZK08_14340)	-	2690250..2691674 (+)	1425	WP_000953736.1	alkaline phosphatase	-
BZK08_RS14480	-	2691744..2691854 (+)	111	WP_001791296.1	hypothetical protein	-
BZK08_RS14010 (BZK08_14350)	-	2691957..2692412 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
BZK08_RS14015 (BZK08_14355)	-	2692656..2693417 (-)	762	WP_084568246.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=216722 BZK08_RS13985 WP_000143420.1 2688263..2689150(-) (braS) [Staphylococcus aureus strain GD1539]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=216722 BZK08_RS13985 WP_000143420.1 2688263..2689150(-) (braS) [Staphylococcus aureus strain GD1539]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993