Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   BVB96_RS20070 Genome accession   NZ_CP018903
Coordinates   3643314..3644093 (-) Length   259 a.a.
NCBI ID   WP_000421288.1    Uniprot ID   Q81WK7
Organism   Bacillus anthracis strain Tyrol 4675     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3608993..3682918 3643314..3644093 within 0


Gene organization within MGE regions


Location: 3608993..3682918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BVB96_RS19905 (BVB96_19905) - 3609336..3611006 (-) 1671 WP_000823085.1 ribonuclease J -
  BVB96_RS19915 (BVB96_19915) dapA 3611772..3612650 (-) 879 WP_000564767.1 4-hydroxy-tetrahydrodipicolinate synthase -
  BVB96_RS19920 (BVB96_19920) dapG 3612662..3613894 (-) 1233 WP_059380665.1 aspartate kinase -
  BVB96_RS19925 (BVB96_19925) asd 3613918..3614964 (-) 1047 WP_000414849.1 aspartate-semialdehyde dehydrogenase -
  BVB96_RS19930 (BVB96_19930) dpaB 3615115..3615714 (-) 600 WP_001049484.1 dipicolinate synthase subunit B -
  BVB96_RS19935 (BVB96_19935) dpaA 3615711..3616613 (-) 903 WP_000954726.1 dipicolinic acid synthetase subunit A -
  BVB96_RS19945 (BVB96_19945) - 3616888..3617139 (-) 252 WP_001239752.1 YlmC/YmxH family sporulation protein -
  BVB96_RS19950 (BVB96_19950) - 3617266..3618507 (-) 1242 WP_000592993.1 M16 family metallopeptidase -
  BVB96_RS19955 (BVB96_19955) - 3618594..3619493 (-) 900 WP_000647529.1 polysaccharide deacetylase family protein -
  BVB96_RS19960 (BVB96_19960) pnp 3619644..3621782 (-) 2139 WP_000076750.1 polyribonucleotide nucleotidyltransferase -
  BVB96_RS19965 (BVB96_19965) rpsO 3621943..3622212 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  BVB96_RS19970 (BVB96_19970) ribF 3622313..3623284 (-) 972 WP_000766711.1 bifunctional riboflavin kinase/FAD synthetase -
  BVB96_RS19975 (BVB96_19975) truB 3623328..3624251 (-) 924 WP_000399357.1 tRNA pseudouridine(55) synthase TruB -
  BVB96_RS19980 (BVB96_19980) rbfA 3624338..3624694 (-) 357 WP_000776441.1 30S ribosome-binding factor RbfA -
  BVB96_RS19985 (BVB96_19985) - 3624710..3624991 (-) 282 WP_000582364.1 DUF503 domain-containing protein -
  BVB96_RS19990 (BVB96_19990) infB 3624988..3627048 (-) 2061 WP_000036340.1 translation initiation factor IF-2 -
  BVB96_RS19995 (BVB96_19995) - 3627053..3627364 (-) 312 WP_001286523.1 YlxQ family RNA-binding protein -
  BVB96_RS20000 (BVB96_20000) rnpM 3627365..3627637 (-) 273 WP_000071128.1 RNase P modulator RnpM -
  BVB96_RS20005 (BVB96_20005) nusA 3627649..3628755 (-) 1107 WP_000102606.1 transcription termination factor NusA -
  BVB96_RS20010 (BVB96_20010) rimP 3628773..3629243 (-) 471 WP_000359097.1 ribosome maturation factor RimP -
  BVB96_RS20015 (BVB96_20015) - 3629576..3633877 (-) 4302 WP_000059985.1 PolC-type DNA polymerase III -
  BVB96_RS20025 (BVB96_20025) - 3634002..3635702 (-) 1701 WP_000814312.1 proline--tRNA ligase -
  BVB96_RS20030 (BVB96_20030) rseP 3635812..3637068 (-) 1257 WP_001090228.1 RIP metalloprotease RseP -
  BVB96_RS20035 (BVB96_20035) dxr 3637085..3638227 (-) 1143 WP_000790359.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  BVB96_RS20040 (BVB96_20040) cdsA 3638251..3639042 (-) 792 WP_000813581.1 phosphatidate cytidylyltransferase -
  BVB96_RS20045 (BVB96_20045) uppS 3639060..3639836 (-) 777 WP_000971301.1 isoprenyl transferase -
  BVB96_RS20050 (BVB96_20050) frr 3639922..3640479 (-) 558 WP_000531503.1 ribosome recycling factor -
  BVB96_RS20055 (BVB96_20055) pyrH 3640482..3641204 (-) 723 WP_000042663.1 UMP kinase -
  BVB96_RS20060 (BVB96_20060) tsf 3641271..3642158 (-) 888 WP_001018581.1 translation elongation factor Ts -
  BVB96_RS20065 (BVB96_20065) rpsB 3642262..3642963 (-) 702 WP_000111483.1 30S ribosomal protein S2 -
  BVB96_RS20070 (BVB96_20070) codY 3643314..3644093 (-) 780 WP_000421288.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  BVB96_RS20075 (BVB96_20075) hslU 3644171..3645562 (-) 1392 WP_000550088.1 ATP-dependent protease ATPase subunit HslU -
  BVB96_RS20080 (BVB96_20080) hslV 3645585..3646127 (-) 543 WP_000526272.1 ATP-dependent protease proteolytic subunit HslV -
  BVB96_RS20085 (BVB96_20085) xerC 3646170..3647069 (-) 900 WP_001101226.1 tyrosine recombinase XerC -
  BVB96_RS20090 (BVB96_20090) trmFO 3647135..3648439 (-) 1305 WP_001991958.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  BVB96_RS20095 (BVB96_20095) topA 3648490..3650568 (-) 2079 WP_001286969.1 type I DNA topoisomerase -
  BVB96_RS20100 (BVB96_20100) dprA 3650713..3651461 (-) 749 Protein_3704 DNA-processing protein DprA -
  BVB96_RS20105 (BVB96_20105) sucD 3651669..3652571 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  BVB96_RS20110 (BVB96_20110) sucC 3652592..3653752 (-) 1161 WP_001020786.1 ADP-forming succinate--CoA ligase subunit beta -
  BVB96_RS20115 (BVB96_20115) rnhB 3653947..3654720 (-) 774 WP_001174712.1 ribonuclease HII -
  BVB96_RS20120 (BVB96_20120) ylqF 3654772..3655662 (-) 891 WP_000236707.1 ribosome biogenesis GTPase YlqF -
  BVB96_RS20125 (BVB96_20125) lepB 3655683..3656234 (-) 552 WP_000711857.1 signal peptidase I -
  BVB96_RS20130 (BVB96_20130) rplS 3656336..3656680 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  BVB96_RS20135 (BVB96_20135) trmD 3656827..3657561 (-) 735 WP_000686892.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  BVB96_RS20140 (BVB96_20140) rimM 3657561..3658076 (-) 516 WP_000170269.1 ribosome maturation factor RimM -
  BVB96_RS20145 (BVB96_20145) - 3658197..3658424 (-) 228 WP_000737398.1 KH domain-containing protein -
  BVB96_RS20150 (BVB96_20150) rpsP 3658439..3658711 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  BVB96_RS20155 (BVB96_20155) ffh 3658812..3660161 (-) 1350 WP_000863456.1 signal recognition particle protein -
  BVB96_RS20160 (BVB96_20160) - 3660174..3660506 (-) 333 WP_000891062.1 putative DNA-binding protein -
  BVB96_RS20165 (BVB96_20165) ftsY 3660640..3661629 (-) 990 WP_000007650.1 signal recognition particle-docking protein FtsY -
  BVB96_RS20170 (BVB96_20170) smc 3661645..3665214 (-) 3570 WP_000478986.1 chromosome segregation protein SMC -
  BVB96_RS20175 (BVB96_20175) rncS 3665361..3666098 (-) 738 WP_001146873.1 ribonuclease III -
  BVB96_RS20180 (BVB96_20180) acpP 3666157..3666390 (-) 234 WP_000786062.1 acyl carrier protein -
  BVB96_RS20185 (BVB96_20185) fabG 3666460..3667200 (-) 741 WP_000911782.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  BVB96_RS20190 (BVB96_20190) fabD 3667200..3668144 (-) 945 WP_000516948.1 ACP S-malonyltransferase -
  BVB96_RS20195 (BVB96_20195) plsX 3668159..3669151 (-) 993 WP_000684111.1 phosphate acyltransferase PlsX -
  BVB96_RS20200 (BVB96_20200) fapR 3669148..3669741 (-) 594 WP_000747352.1 transcription factor FapR -
  BVB96_RS20205 (BVB96_20205) recG 3669830..3671878 (-) 2049 WP_001006884.1 ATP-dependent DNA helicase RecG -
  BVB96_RS20210 (BVB96_20210) - 3672168..3673844 (-) 1677 WP_000027140.1 DAK2 domain-containing protein -
  BVB96_RS20215 (BVB96_20215) - 3673867..3674229 (-) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  BVB96_RS20220 (BVB96_20220) rpmB 3674608..3674796 (+) 189 WP_000124778.1 50S ribosomal protein L28 -
  BVB96_RS20225 (BVB96_20225) spoVM 3674870..3674950 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  BVB96_RS20230 (BVB96_20230) - 3675017..3675697 (-) 681 WP_025388434.1 thiamine diphosphokinase -
  BVB96_RS20235 (BVB96_20235) rpe 3675797..3676441 (-) 645 WP_000589966.1 ribulose-phosphate 3-epimerase -
  BVB96_RS20240 (BVB96_20240) rsgA 3676444..3677325 (-) 882 WP_001113935.1 ribosome small subunit-dependent GTPase A -
  BVB96_RS20245 (BVB96_20245) prkC 3677594..3679567 (-) 1974 WP_000904759.1 serine/threonine protein kinase PrkC -
  BVB96_RS20250 (BVB96_20250) - 3679576..3680328 (-) 753 WP_000648699.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  BVB96_RS20255 (BVB96_20255) rlmN 3680333..3681421 (-) 1089 WP_000450543.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  BVB96_RS20260 (BVB96_20260) rsmB 3681426..3682760 (-) 1335 WP_001249680.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28774.05 Da        Isoelectric Point: 4.7947

>NTDB_id=211599 BVB96_RS20070 WP_000421288.1 3643314..3644093(-) (codY) [Bacillus anthracis strain Tyrol 4675]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=211599 BVB96_RS20070 WP_000421288.1 3643314..3644093(-) (codY) [Bacillus anthracis strain Tyrol 4675]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGTCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAGAATGAGCGTATGAAACAAATGCTTGCAGAACGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAAGAAGCACGTAGCAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAATTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCGGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTATTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81WK7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.081

100

0.811
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459

Multiple sequence alignment