Detailed information NTG0206847

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: BSR19_RS04900
• Genome accession: NZ_CP018187
• Coordinates: 979390..980271 (+)
• Length: 293 a.a.
• NCBI ID: WP_060972710.1
• Uniprot ID: A0AB37D9X2
• Organism: Streptococcus salivarius strain ICDC2
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 974390..985271

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSR19_RS04875 (BSR19_04945)	-	974922..976343 (+)	1422	WP_156246671.1	DUF4832 domain-containing protein	-
BSR19_RS04880 (BSR19_04950)	galE	976358..977371 (+)	1014	WP_021144269.1	UDP-glucose 4-epimerase GalE	-
BSR19_RS04885 (BSR19_04955)	-	977563..977799 (+)	237	WP_002890830.1	DUF1146 family protein	-
BSR19_RS04890 (BSR19_04960)	murA	977867..979138 (+)	1272	WP_060972709.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
BSR19_RS04895 (BSR19_04965)	-	979140..979328 (+)	189	WP_003097027.1	DNA-directed RNA polymerase subunit beta	-
BSR19_RS04900 (BSR19_04970)	endA	979390..980271 (+)	882	WP_060972710.1	DNA/RNA non-specific endonuclease	Machinery gene
BSR19_RS04905 (BSR19_04975)	-	980349..980999 (-)	651	WP_002890834.1	amino acid ABC transporter permease	-
BSR19_RS04910 (BSR19_04980)	-	981011..981709 (-)	699	WP_002886251.1	amino acid ABC transporter permease	-
BSR19_RS04915 (BSR19_04985)	-	981727..982560 (-)	834	WP_004182612.1	transporter substrate-binding domain-containing protein	-
BSR19_RS04920 (BSR19_04990)	-	982572..983339 (-)	768	WP_156246672.1	amino acid ABC transporter ATP-binding protein	-
BSR19_RS04925 (BSR19_04995)	-	983528..984178 (-)	651	WP_037601175.1	amino acid ABC transporter permease	-
BSR19_RS04930 (BSR19_05000)	-	984190..984888 (-)	699	WP_002886251.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31504.12 Da
• Isoelectric Point: 10.2036

>NTDB_id=206847 BSR19_RS04900 WP_060972710.1 979390..980271(+) (endA) [Streptococcus salivarius strain ICDC2]
MAKRKTSLTNKQKRQLVSLLIAVLIAVLGYIGTSNKLSPNNPIKQVASLVSGKSNNSVKSNGSTNGKATPQEQLAESVMT
SSVKSQLGNSIEWNGAGAYIVNGNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVHNLSGEYSHAVDRGHLLGYALVGGLKGFDASTSNPENIAVQTAWANQANSESSTGQNYYESLVRKAQDKNKRVR
YRVTLIYEGDNLIPSGSHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=206847 BSR19_RS04900 WP_060972710.1 979390..980271(+) (endA) [Streptococcus salivarius strain ICDC2]
ATGGCAAAAAGAAAGACATCTTTAACAAATAAACAGAAACGTCAGCTAGTCTCGTTACTAATAGCGGTCTTGATTGCAGT
TTTAGGTTACATTGGGACGAGCAATAAGCTATCGCCTAATAATCCAATCAAGCAGGTAGCTAGTCTAGTCTCGGGAAAAT
CCAATAACTCCGTCAAATCAAACGGTTCAACAAATGGAAAGGCTACGCCACAGGAGCAGCTTGCTGAGTCAGTGATGACT
AGCTCCGTCAAGAGTCAACTAGGAAATTCCATAGAATGGAATGGGGCAGGGGCTTATATTGTTAATGGTAATAAAACTAA
TCTAAATGCTAAGGTTTCTAGCCAACCCTATGCCAATAACCAAGTCAAAACGGTTCAAGGACAAACGGTTCCAACAGTTG
CGAATGCCTTATTAAGTAAAGCAACCAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGCTCAACCTCTTGGACACCT
GCGGGATGGCATCAAGTTCACAATCTTTCAGGAGAGTATAGCCACGCCGTAGATAGAGGTCATTTGTTAGGCTATGCACT
TGTAGGTGGTCTCAAAGGATTTGATGCCTCGACTTCAAATCCAGAAAATATTGCCGTTCAAACTGCTTGGGCTAACCAAG
CTAATAGCGAAAGTTCTACGGGACAAAACTATTATGAAAGCCTGGTACGAAAGGCTCAGGATAAAAACAAACGTGTCCGT
TATCGCGTTACCCTAATTTATGAAGGGGATAACCTCATTCCATCAGGATCACATCTTGAAGCCAAGTCAGCTGATGGCTC
ACTTGAGTTCAATGTCTTTGTTCCAAATGTACAAGAAGGGATTACCCTAGATTATTATTCAGGAAAAGTAACGGTGAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (99-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	71.146	86.348	0.614
endA	Streptococcus pneumoniae D39	71.146	86.348	0.614
endA	Streptococcus pneumoniae R6	71.146	86.348	0.614
endA	Streptococcus pneumoniae TIGR4	71.146	86.348	0.614