Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   LL158_RS07690 Genome accession   NZ_CP015894
Coordinates   1528571..1529263 (-) Length   230 a.a.
NCBI ID   WP_081213187.1    Uniprot ID   -
Organism   Lactococcus cremoris strain 158     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1523571..1534263
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LL158_RS07670 (LL158_1481) murD 1523715..1525064 (-) 1350 WP_015082642.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  LL158_RS07675 (LL158_1482) - 1525233..1525574 (-) 342 WP_011676628.1 P-II family nitrogen regulator -
  LL158_RS07680 (LL158_1483) - 1525659..1526900 (-) 1242 WP_015082643.1 ammonium transporter -
  LL158_RS07685 (LL158_1484) covS 1527086..1528558 (-) 1473 WP_021211938.1 HAMP domain-containing histidine kinase Regulator
  LL158_RS07690 (LL158_1485) covR 1528571..1529263 (-) 693 WP_081213187.1 response regulator transcription factor Regulator
  LL158_RS07695 (LL158_1486) - 1529419..1529949 (-) 531 WP_011834860.1 DUF177 domain-containing protein -
  LL158_RS07700 (LL158_1487) - 1530082..1530327 (-) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  LL158_RS07705 (LL158_02990) - 1530651..1531013 (-) 363 Protein_1496 TIGR02328 family protein -
  LL158_RS07710 (LL158_1488) - 1531161..1531712 (+) 552 WP_021214392.1 Ltp family lipoprotein -
  LL158_RS07715 (LL158_1489) - 1531820..1532590 (+) 771 WP_015082647.1 hypothetical protein -
  LL158_RS07720 (LL158_1490) - 1532751..1533824 (-) 1074 WP_011676639.1 carbamoyl phosphate synthase small subunit -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26654.29 Da        Isoelectric Point: 5.0082

>NTDB_id=182830 LL158_RS07690 WP_081213187.1 1528571..1529263(-) (covR) [Lactococcus cremoris strain 158]
MASKKILIIEDEKNLARFVSLELEHEGYATEIKDNGRSGLEEATSKDYDLILLDLMLPELDGFEVARRLRKEKDTPIIMM
TARDSTMERVAGLDIGADDYITNPFAIEELLARVRAFFRREEHGHAVERAENTSFRDLVIDKTNRTVHRGKKVIDLTRRE
YDLLLTLMQNVGDVVTREHLVSQVWGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRERK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=182830 LL158_RS07690 WP_081213187.1 1528571..1529263(-) (covR) [Lactococcus cremoris strain 158]
ATGGCATCAAAGAAAATTTTGATTATTGAGGATGAAAAGAATTTAGCTCGTTTCGTCTCATTAGAATTAGAGCATGAAGG
CTATGCCACTGAGATTAAAGATAACGGACGTTCTGGGCTTGAAGAAGCAACTTCAAAAGATTATGATTTAATCTTGCTTG
ATTTGATGCTTCCTGAACTTGATGGTTTTGAAGTTGCCCGCCGTTTGCGCAAAGAAAAAGATACTCCAATTATTATGATG
ACCGCGCGTGATTCAACAATGGAACGTGTTGCCGGTCTTGATATTGGAGCAGATGATTATATTACTAATCCTTTTGCGAT
TGAAGAACTTTTGGCTCGTGTTCGTGCATTCTTCCGTCGTGAAGAACATGGTCATGCTGTAGAACGTGCTGAAAACACTT
CTTTTCGTGATCTTGTAATTGACAAAACAAATCGTACCGTTCACCGCGGTAAAAAAGTAATTGATTTGACGCGTCGTGAA
TACGATCTTCTTTTGACGTTGATGCAAAATGTTGGGGATGTTGTCACTCGCGAACATTTAGTTTCACAAGTTTGGGGATA
TGAAGAAGGAACGGAAACAAATGTTGTTGATGTATATATCCGCTATCTTAGAAATAAAATTGATGTTGAAGGACAAGACA
GCTATATTCAAACCGTTCGTGGTTTGGGTTATGTGATGCGTGAACGCAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-115)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

98.696

100

0.987
  covR Streptococcus salivarius strain HSISS4

67.544

99.13

0.67
  vicR Streptococcus mutans UA159

45.022

100

0.452
  micA Streptococcus pneumoniae Cp1015

42.609

100

0.426
  ciaR Streptococcus mutans UA159

36.726

98.261

0.361

Multiple sequence alignment