Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   AWB63_RS09270 Genome accession   NZ_CP014144
Coordinates   2020762..2021997 (-) Length   411 a.a.
NCBI ID   WP_037611167.1    Uniprot ID   A0AB33ZFB7
Organism   Streptococcus salivarius strain JF     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2015762..2026997
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AWB63_RS09250 (AWB63_09250) - 2016791..2016982 (-) 192 WP_002883961.1 DUF951 domain-containing protein -
  AWB63_RS09255 (AWB63_09255) dnaN 2017034..2018170 (-) 1137 WP_002883965.1 DNA polymerase III subunit beta -
  AWB63_RS09260 (AWB63_09260) dnaA 2018325..2019689 (-) 1365 WP_002883970.1 chromosomal replication initiator protein DnaA -
  AWB63_RS09265 (AWB63_09265) spo0J 2019928..2020695 (-) 768 WP_038676938.1 ParB/RepB/Spo0J family partition protein Regulator
  AWB63_RS09270 (AWB63_09270) htrA 2020762..2021997 (-) 1236 WP_037611167.1 S1C family serine protease Regulator
  AWB63_RS09275 (AWB63_09275) rlmH 2022203..2022682 (+) 480 WP_022495861.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  AWB63_RS09280 (AWB63_09280) - 2022698..2023381 (+) 684 WP_038676936.1 YoaK family protein -
  AWB63_RS09300 (AWB63_09300) - 2023936..2026530 (-) 2595 WP_038676934.1 YfhO family protein -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 42958.12 Da        Isoelectric Point: 4.6266

>NTDB_id=168769 AWB63_RS09270 WP_037611167.1 2020762..2021997(-) (htrA) [Streptococcus salivarius strain JF]
MKKFNWKKIVAPIAMLVIGLLGGLLGAFILLTAAGVSFTNSTDTGVKTAKTVYNNTTDTTKAVKKVQNAVVSVINYQEGS
SSDSLNELYGRIFGGDDSSDSNQDKSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKIKTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTVTMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISMADLNSLS
SSATSKLDLPDDVKSGVVVGSVQKGMPADGKLQENDVITEIDGKEISSKTDIQTNLYSHSIGDTIKVTFYRGKEKKTEEL
KLTKSTEDLSD

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=168769 AWB63_RS09270 WP_037611167.1 2020762..2021997(-) (htrA) [Streptococcus salivarius strain JF]
GTGAAAAAATTTAACTGGAAAAAAATAGTAGCGCCGATTGCAATGCTTGTTATTGGCTTACTAGGTGGTTTACTAGGTGC
CTTTATCCTACTAACAGCAGCAGGGGTATCTTTTACCAATTCAACAGATACAGGTGTTAAAACAGCTAAGACCGTATACA
ATAATACAACAGATACAACTAAAGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTACCAAGAAGGGTCA
TCTTCAGATTCTCTAAATGAACTTTATGGCCGTATCTTTGGTGGAGATGATAGTTCTGACTCTAACCAAGACAAATCAAA
AGATTCTGATGGGTTACAAGTCGCTGGTGAAGGTTCCGGTGTTATCTATAAAAAGGATGGTAAAGAGGCTTATATCGTAA
CCAACAACCACGTTGTCGATGGCGCTAAAAAACTTGAAATCATGCTTTCAGATGGATCAAAAATTACTGGTGAACTCGTT
GGTAAAGATACTTACTCTGACCTAGCAGTTGTCAAAGTTTCTTCAGATAAAATTAAAACCGTAGCGGAATTTGCAGACTC
AAACTCTCTCACAGTCGGTGAGAAGGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAGG
GAATCGTTTCTAGCCTTAGCCGTACCGTAACTATGCAAAACGACAATGGTGAAACTGTTTCAACAAATGCTATCCAAACG
GATGCTGCCATTAACCCTGGTAACTCAGGTGGTGCCTTAGTCAATATCGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACATCAGCAGTCGCTGGTAGCGCCGTTGAAGGTATGGGATTTGCCATTCCATCAAACGATGTTGTCGAGA
TTATCAATCAATTGGAAAAAGACGGTAAAGTTACACGACCAGCCCTAGGAATCTCAATGGCCGATCTTAATAGCCTTTCT
AGCAGTGCAACTTCTAAATTAGATTTACCAGATGATGTGAAATCTGGAGTGGTAGTCGGCAGCGTTCAAAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAAAATGATGTTATCACTGAAATTGACGGTAAGGAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACAATCAAGGTAACCTTCTATCGTGGTAAAGAGAAGAAAACTGAAGAACTT
AAATTAACAAAATCTACAGAAGACTTGTCTGACTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(307-402)

Trypsin-like peptidase domain (Trypsin_2)

(118-263)

Peptidase family M50 (Peptidase_M50)

(7-406)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.787

98.054

0.606
  htrA Streptococcus gordonii str. Challis substr. CH1

57.635

98.783

0.569
  htrA Streptococcus pneumoniae Rx1

54.523

99.513

0.543
  htrA Streptococcus pneumoniae R6

54.523

99.513

0.543
  htrA Streptococcus pneumoniae TIGR4

54.523

99.513

0.543
  htrA Streptococcus pneumoniae D39

54.523

99.513

0.543
  htrA Streptococcus mitis NCTC 12261

54.523

99.513

0.543

Multiple sequence alignment