Detailed information
Bioinformatically predicted
Overview
| Name | prx | Type | Regulator |
| Locus tag | AL510_RS07395 | Genome accession | NZ_CP014027 |
| Coordinates | 1435865..1436047 (+) | Length | 60 a.a. |
| NCBI ID | WP_011054671.1 | Uniprot ID | Q4VUT1 |
| Organism | Streptococcus pyogenes strain FDAARGOS_149 | ||
| Function | Inhibit ComR activation (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1401497..1436047 | 1435865..1436047 | within | 0 |
Gene organization within MGE regions
Location: 1401497..1436047
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AL510_RS07140 (AL510_06920) | - | 1401497..1401772 (+) | 276 | WP_002983920.1 | HU family DNA-binding protein | - |
| AL510_RS07145 (AL510_06925) | - | 1401861..1403003 (-) | 1143 | WP_003051793.1 | tyrosine-type recombinase/integrase | - |
| AL510_RS07150 (AL510_06930) | - | 1403127..1403645 (-) | 519 | WP_010922481.1 | HIRAN domain-containing protein | - |
| AL510_RS07155 (AL510_06935) | - | 1403657..1404412 (-) | 756 | WP_010922480.1 | helix-turn-helix domain-containing protein | - |
| AL510_RS07160 (AL510_06940) | - | 1404614..1404826 (+) | 213 | WP_010922479.1 | helix-turn-helix domain-containing protein | - |
| AL510_RS07165 (AL510_06945) | - | 1405096..1405407 (+) | 312 | WP_010922478.1 | excisionase | - |
| AL510_RS07170 (AL510_06950) | - | 1405409..1405594 (+) | 186 | WP_061046295.1 | hypothetical protein | - |
| AL510_RS09825 (AL510_06955) | - | 1405703..1405957 (+) | 255 | WP_011528797.1 | replication protein | - |
| AL510_RS07180 (AL510_06960) | - | 1406098..1406484 (+) | 387 | WP_011017564.1 | DnaD domain-containing protein | - |
| AL510_RS07185 (AL510_06965) | - | 1406465..1406698 (+) | 234 | WP_002985387.1 | hypothetical protein | - |
| AL510_RS07190 (AL510_09525) | - | 1406695..1406835 (+) | 141 | WP_011017992.1 | hypothetical protein | - |
| AL510_RS07195 (AL510_06970) | - | 1406844..1407050 (+) | 207 | WP_011017565.1 | hypothetical protein | - |
| AL510_RS07200 (AL510_06975) | - | 1407106..1407438 (+) | 333 | WP_010922475.1 | hypothetical protein | - |
| AL510_RS07205 (AL510_06980) | - | 1407438..1408427 (+) | 990 | WP_010922474.1 | recombinase RecT | - |
| AL510_RS07210 (AL510_06985) | - | 1408424..1408624 (+) | 201 | WP_000594115.1 | hypothetical protein | - |
| AL510_RS07215 (AL510_06990) | - | 1408617..1409414 (+) | 798 | WP_011054699.1 | PD-(D/E)XK nuclease-like domain-containing protein | - |
| AL510_RS07220 (AL510_06995) | - | 1409779..1410174 (+) | 396 | WP_011054698.1 | Cas9 inhibitor AcrIIA9 family protein | - |
| AL510_RS07225 (AL510_07000) | - | 1410171..1411517 (+) | 1347 | WP_011054697.1 | PcfJ domain-containing protein | - |
| AL510_RS07230 (AL510_07005) | - | 1411528..1411860 (+) | 333 | WP_011054696.1 | hypothetical protein | - |
| AL510_RS07235 (AL510_07010) | - | 1411857..1412369 (+) | 513 | WP_011054695.1 | hypothetical protein | - |
| AL510_RS07240 (AL510_07015) | - | 1412405..1412722 (+) | 318 | WP_011054694.1 | DUF1372 family protein | - |
| AL510_RS09545 | - | 1412719..1412874 (+) | 156 | WP_011054693.1 | hypothetical protein | - |
| AL510_RS07245 (AL510_07020) | - | 1412871..1413122 (+) | 252 | WP_011054692.1 | hypothetical protein | - |
| AL510_RS07250 (AL510_07025) | - | 1413198..1413617 (+) | 420 | WP_011054691.1 | DUF1492 domain-containing protein | - |
| AL510_RS07255 (AL510_07030) | - | 1413725..1414069 (+) | 345 | WP_011054690.1 | HNH endonuclease signature motif containing protein | - |
| AL510_RS07260 (AL510_07035) | - | 1414217..1414573 (+) | 357 | WP_002994106.1 | hypothetical protein | - |
| AL510_RS07265 (AL510_07040) | - | 1414570..1415838 (+) | 1269 | WP_010922468.1 | phage portal protein | - |
| AL510_RS07270 (AL510_07045) | - | 1415831..1417324 (+) | 1494 | WP_010922467.1 | hypothetical protein | - |
| AL510_RS07275 (AL510_07050) | - | 1417330..1417554 (+) | 225 | WP_002994100.1 | hypothetical protein | - |
| AL510_RS09550 | - | 1417631..1417783 (+) | 153 | WP_011054687.1 | hypothetical protein | - |
| AL510_RS07280 (AL510_07055) | - | 1417776..1418042 (+) | 267 | WP_002986828.1 | hypothetical protein | - |
| AL510_RS07285 (AL510_07060) | - | 1418044..1418259 (+) | 216 | WP_011106704.1 | hypothetical protein | - |
| AL510_RS07290 (AL510_07065) | - | 1418341..1419756 (+) | 1416 | WP_011054685.1 | terminase | - |
| AL510_RS07295 (AL510_07070) | - | 1419837..1420298 (+) | 462 | WP_011054684.1 | capsid assembly scaffolding protein Gp46 family protein | - |
| AL510_RS07300 (AL510_07075) | - | 1420323..1421234 (+) | 912 | WP_011054683.1 | phage major capsid protein | - |
| AL510_RS07305 (AL510_07080) | - | 1421234..1421434 (+) | 201 | WP_010922460.1 | hypothetical protein | - |
| AL510_RS07310 (AL510_07085) | - | 1421444..1421866 (+) | 423 | WP_011054682.1 | phage Gp19/Gp15/Gp42 family protein | - |
| AL510_RS07315 (AL510_07090) | - | 1421826..1422164 (+) | 339 | WP_011054681.1 | hypothetical protein | - |
| AL510_RS07320 (AL510_07095) | - | 1422157..1422393 (+) | 237 | WP_000032787.1 | hypothetical protein | - |
| AL510_RS07325 (AL510_07100) | - | 1422394..1422729 (+) | 336 | WP_000573598.1 | hypothetical protein | - |
| AL510_RS07330 (AL510_07105) | - | 1422745..1423335 (+) | 591 | WP_011054679.1 | hypothetical protein | - |
| AL510_RS07335 (AL510_07110) | - | 1423346..1423609 (+) | 264 | WP_010922455.1 | hypothetical protein | - |
| AL510_RS07340 (AL510_07115) | - | 1423624..1423995 (+) | 372 | WP_011054678.1 | DUF5361 domain-containing protein | - |
| AL510_RS07345 (AL510_07120) | - | 1423995..1426358 (+) | 2364 | WP_011054677.1 | phage tail protein | - |
| AL510_RS07350 (AL510_07125) | - | 1426355..1427050 (+) | 696 | WP_002992579.1 | hypothetical protein | - |
| AL510_RS07355 (AL510_07130) | - | 1427032..1429005 (+) | 1974 | WP_011054676.1 | phage tail spike protein | - |
| AL510_RS07360 (AL510_07135) | - | 1429005..1430114 (+) | 1110 | WP_011054675.1 | hyaluronoglucosaminidase | - |
| AL510_RS07365 (AL510_07140) | - | 1430129..1431910 (+) | 1782 | WP_011054674.1 | gp58-like family protein | - |
| AL510_RS07370 (AL510_07145) | - | 1431919..1432350 (+) | 432 | WP_011054673.1 | DUF1617 family protein | - |
| AL510_RS07375 (AL510_07150) | - | 1432353..1432967 (+) | 615 | WP_011054672.1 | DUF1366 domain-containing protein | - |
| AL510_RS07380 (AL510_07155) | - | 1432978..1433433 (+) | 456 | WP_002983475.1 | phage holin family protein | - |
| AL510_RS07385 (AL510_07160) | - | 1433545..1434759 (+) | 1215 | WP_002983477.1 | peptidoglycan amidohydrolase family protein | - |
| AL510_RS07390 (AL510_07165) | - | 1435004..1435798 (+) | 795 | WP_002983479.1 | DNA/RNA non-specific endonuclease | - |
| AL510_RS07395 (AL510_07170) | prx | 1435865..1436047 (+) | 183 | WP_011054671.1 | hypothetical protein | Regulator |
Sequence
Protein
Download Length: 60 a.a. Molecular weight: 6978.99 Da Isoelectric Point: 4.3466
>NTDB_id=167532 AL510_RS07395 WP_011054671.1 1435865..1436047(+) (prx) [Streptococcus pyogenes strain FDAARGOS_149]
MLTYDEFKQAIDRGYITADTVMIVRKNGQIFDYVLPNEKIKNGEIVTDEKVEEVLVELSR
MLTYDEFKQAIDRGYITADTVMIVRKNGQIFDYVLPNEKIKNGEIVTDEKVEEVLVELSR
Nucleotide
Download Length: 183 bp
>NTDB_id=167532 AL510_RS07395 WP_011054671.1 1435865..1436047(+) (prx) [Streptococcus pyogenes strain FDAARGOS_149]
ATGCTAACATACGACGAATTTAAGCAAGCTATTGACCGTGGATATATCACAGCAGACACAGTAATGATCGTGCGCAAGAA
CGGACAGATTTTTGATTATGTGTTGCCGAATGAGAAGATAAAGAATGGAGAAATTGTGACAGACGAAAAAGTGGAAGAGG
TGCTGGTGGAGCTTTCGAGATAA
ATGCTAACATACGACGAATTTAAGCAAGCTATTGACCGTGGATATATCACAGCAGACACAGTAATGATCGTGCGCAAGAA
CGGACAGATTTTTGATTATGTGTTGCCGAATGAGAAGATAAAGAATGGAGAAATTGTGACAGACGAAAAAGTGGAAGAGG
TGCTGGTGGAGCTTTCGAGATAA
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| prx | Streptococcus pyogenes MGAS315 |
100 |
100 |
1 |
| prx | Streptococcus pyogenes MGAS8232 |
85 |
100 |
0.85 |
| prx | Streptococcus pyogenes MGAS315 |
78.333 |
100 |
0.783 |
| prx | Streptococcus pyogenes MGAS315 |
73.333 |
100 |
0.733 |
| prx | Streptococcus pyogenes MGAS315 |
83.721 |
71.667 |
0.6 |
| prx | Streptococcus pyogenes MGAS315 |
82.927 |
68.333 |
0.567 |
| prx | Streptococcus pyogenes MGAS315 |
71.429 |
70 |
0.5 |