Detailed information NTG0137334

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: SD89_RS04415
• Genome accession: NZ_CP010449
• Coordinates: 897747..898583 (+)
• Length: 278 a.a.
• NCBI ID: WP_014407585.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NGAS322
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 892747..903583

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SD89_RS04385 (SD89_04385)	-	893295..893669 (+)	375	WP_011054498.1	hypothetical protein	-
SD89_RS04390 (SD89_04390)	-	893719..894630 (-)	912	WP_002984631.1	diacylglycerol/lipid kinase family protein	-
SD89_RS04395 (SD89_04395)	trhA	894747..895397 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
SD89_RS04400 (SD89_04400)	-	895394..895834 (-)	441	WP_002984627.1	DUF1836 domain-containing protein	-
SD89_RS04405 (SD89_04405)	ylqF	896053..896901 (+)	849	WP_053308360.1	ribosome biogenesis GTPase YlqF	-
SD89_RS04410 (SD89_04410)	-	896891..897682 (+)	792	WP_053308361.1	ribonuclease HII	-
SD89_RS04415 (SD89_04415)	dprA	897747..898583 (+)	837	WP_014407585.1	DNA-processing protein DprA	Machinery gene
SD89_RS04420 (SD89_04420)	topA	898691..900820 (+)	2130	WP_014407586.1	type I DNA topoisomerase	-
SD89_RS10265	-	900895..901752 (-)	858	Protein_811	LysR family transcriptional regulator	-
SD89_RS04430 (SD89_04430)	-	901792..902358 (+)	567	Protein_812	PTS sugar transporter subunit IIC	-
SD89_RS04435 (SD89_04435)	-	902373..903365 (+)	993	WP_009880715.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30988.94 Da
• Isoelectric Point: 8.8230

>NTDB_id=137334 SD89_RS04415 WP_014407585.1 897747..898583(+) (dprA) [Streptococcus pyogenes strain NGAS322]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=137334 SD89_RS04415 WP_014407585.1 897747..898583(+) (dprA) [Streptococcus pyogenes strain NGAS322]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367