Detailed information NTG0122403

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EQ90_RS10030
• Genome accession: NZ_CP007674
• Coordinates: 1992407..1993450 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain CA15
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1987407..1998450

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQ90_RS10000 (EQ90_09515)	-	1987825..1989081 (-)	1257	WP_001795438.1	aminopeptidase	-
EQ90_RS10005 (EQ90_09520)	-	1989084..1989284 (-)	201	WP_000180461.1	DUF1128 family protein	-
EQ90_RS10010 (EQ90_09525)	-	1989431..1989895 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
EQ90_RS10015 (EQ90_09530)	-	1989902..1990177 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
EQ90_RS10020 (EQ90_09535)	-	1990455..1991672 (+)	1218	WP_047339382.1	YihY/virulence factor BrkB family protein	-
EQ90_RS10025 (EQ90_09540)	vraR	1991788..1992417 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
EQ90_RS10030 (EQ90_09545)	vraS	1992407..1993450 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
EQ90_RS10035 (EQ90_09550)	liaF	1993447..1994148 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
EQ90_RS10040 (EQ90_09555)	-	1994163..1994549 (-)	387	WP_001110179.1	hypothetical protein	-
EQ90_RS10045 (EQ90_09560)	map	1994766..1995524 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
EQ90_RS10055 (EQ90_09565)	-	1996052..1997038 (+)	987	WP_000999713.1	FUSC family protein	-
EQ90_RS10060 (EQ90_09570)	-	1997469..1997882 (-)	414	WP_001549145.1	hypothetical protein	-
EQ90_RS15850	-	1997911..1998021 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=122403 EQ90_RS10030 WP_001017131.1 1992407..1993450(-) (vraS) [Staphylococcus aureus strain CA15]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=122403 EQ90_RS10030 WP_001017131.1 1992407..1993450(-) (vraS) [Staphylococcus aureus strain CA15]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1