Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   NTHI723_RS06225 Genome accession   NZ_CP007472
Coordinates   1258936..1259733 (+) Length   265 a.a.
NCBI ID   WP_011272050.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 723     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1253936..1264733
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NTHI723_RS06205 (NTHI723_01246) recR 1254094..1254696 (-) 603 WP_005626527.1 recombination mediator RecR -
  NTHI723_RS06210 (NTHI723_01247) - 1254827..1255156 (-) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -
  NTHI723_RS06215 (NTHI723_01248) - 1255325..1256170 (-) 846 WP_011272052.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  NTHI723_RS06220 (NTHI723_01249) - 1256243..1258837 (-) 2595 WP_044364772.1 penicillin-binding protein 1A -
  NTHI723_RS06225 (NTHI723_01250) comA 1258936..1259733 (+) 798 WP_011272050.1 pilus assembly protein PilM Machinery gene
  NTHI723_RS06230 (NTHI723_01251) comB 1259734..1260240 (+) 507 WP_011272049.1 competence protein ComB Machinery gene
  NTHI723_RS06235 (NTHI723_01252) comC 1260237..1260758 (+) 522 WP_011272048.1 competence protein ComC Machinery gene
  NTHI723_RS06240 (NTHI723_01253) comD 1260755..1261168 (+) 414 WP_011272047.1 pilus assembly protein PilP Machinery gene
  NTHI723_RS06245 (NTHI723_01254) comE 1261178..1262515 (+) 1338 WP_011272046.1 type IV pilus secretin PilQ Machinery gene
  NTHI723_RS06250 (NTHI723_01255) - 1262528..1263214 (+) 687 WP_011272045.1 ComF family protein -
  NTHI723_RS06255 (NTHI723_01256) nfuA 1263290..1263886 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -

Sequence

Protein


Download         Length: 265 a.a.        Molecular weight: 31392.66 Da        Isoelectric Point: 6.2334

>NTDB_id=119773 NTHI723_RS06225 WP_011272050.1 1258936..1259733(+) (comA) [Haemophilus influenzae strain 723]
MQFSLKNYRTLQIGIHRKQGYFDFVWFDDLEQPQSYQIFVNDRDFKNRFLQQLKTQYQGKTFPLQFVASIPAHLTWSKVL
MLPQVLNAQECHQQCKFVIEKELPISLNELWFDYRSTSLKQGFRLDVTAIRKSTAQTYLQDFQPFKINVLDVASNAILRA
FQYLLNEQVRSENTLFLFQEDDYCLAICERSQQSQILQSHENLTALYEQFTERFEGQLEQVFVYQIPSSHTPLPENWQRV
ETELPFIALGNALWQKDLHQQKVGG

Nucleotide


Download         Length: 798 bp        

>NTDB_id=119773 NTHI723_RS06225 WP_011272050.1 1258936..1259733(+) (comA) [Haemophilus influenzae strain 723]
ATGCAATTCTCCCTGAAAAATTACCGCACTTTACAAATCGGCATTCATCGTAAGCAGGGTTATTTTGATTTTGTGTGGTT
TGATGATCTTGAACAGCCACAAAGTTATCAAATTTTTGTTAATGATCGTGATTTTAAAAATCGTTTTTTACAACAGCTAA
AAACACAATATCAAGGGAAAACCTTTCCTTTACAGTTTGTGGCAAGCATTCCCGCTCACTTAACTTGGTCGAAAGTATTA
ATGTTGCCACAAGTGTTAAATGCGCAAGAATGTCATCAACAATGTAAATTTGTGATTGAAAAAGAGCTGCCTATTTCTTT
AAATGAATTATGGTTTGATTATCGTTCTACCTCGTTAAAGCAAGGTTTTCGATTAGACGTTACTGCAATTCGTAAAAGTA
CTGCTCAAACTTATTTGCAAGATTTTCAGCCATTTAAAATTAATGTATTGGATGTTGCGTCAAATGCTATTTTGCGTGCA
TTTCAGTATTTGTTGAATGAACAAGTGCGGTCAGAAAATACCTTATTTTTATTTCAAGAAGATGACTATTGTTTGGCGAT
CTGTGAAAGATCGCAGCAATCGCAAATTTTACAATCTCACGAAAATTTGACCGCACTTTATGAACAATTTACCGAACGTT
TTGAAGGACAACTTGAACAAGTTTTTGTTTATCAAATTCCCTCAAGTCATACACCATTACCCGAAAACTGGCAGCGAGTA
GAAACAGAACTCCCTTTTATTGCGCTTGGCAACGCGCTATGGCAAAAAGATTTACATCAACAAAAAGTGGGTGGTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Haemophilus influenzae 86-028NP

100

100

1
  comA Haemophilus influenzae Rd KW20

96.226

100

0.962

Multiple sequence alignment