Detailed information NTG0117149

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AZ30_RS14560
• Genome accession: NZ_CP007176
• Coordinates: 2817304..2818191 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus USA300-ISMMS1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2812304..2823191

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AZ30_RS14525	-	2812323..2812415 (+)	93	WP_010956583.1	hypothetical protein	-
AZ30_RS14530 (AZ30_13710)	-	2812523..2813020 (-)	498	WP_001065268.1	glutathione peroxidase	-
AZ30_RS14535	-	2813030..2813290 (-)	261	WP_001789910.1	hypothetical protein	-
AZ30_RS14540	-	2813672..2813785 (-)	114	WP_001791776.1	hypothetical protein	-
AZ30_RS14550 (AZ30_13715)	-	2814444..2816444 (-)	2001	WP_000776751.1	ABC transporter permease	-
AZ30_RS14555 (AZ30_13720)	-	2816441..2817196 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AZ30_RS14560 (AZ30_13725)	braS	2817304..2818191 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AZ30_RS14565 (AZ30_13730)	braR	2818202..2818867 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AZ30_RS14570 (AZ30_13735)	-	2818893..2819093 (-)	201	WP_000604728.1	hypothetical protein	-
AZ30_RS14580 (AZ30_13740)	-	2819291..2820715 (+)	1425	WP_000953744.1	alkaline phosphatase	-
AZ30_RS16450 (AZ30_13745)	-	2820775..2820876 (-)	102	WP_000731972.1	SE2200 family small protein	-
AZ30_RS14585 (AZ30_13750)	-	2820998..2821453 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AZ30_RS14590 (AZ30_13755)	-	2821698..2822459 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=117149 AZ30_RS14560 WP_000143419.1 2817304..2818191(-) (braS) [Staphylococcus aureus USA300-ISMMS1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=117149 AZ30_RS14560 WP_000143419.1 2817304..2818191(-) (braS) [Staphylococcus aureus USA300-ISMMS1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997