Detailed information NTG1165403

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACE4RH_RS14100
• Genome accession: NZ_OZ059824
• Coordinates: 2762692..2763579 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus isolate E3_22S00626-1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2757692..2768579

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACE4RH_RS14070	-	2757703..2757795 (+)	93	WP_031774855.1	hypothetical protein	-
ACE4RH_RS14075	-	2757903..2758400 (-)	498	WP_001065267.1	glutathione peroxidase	-
ACE4RH_RS14080	-	2758410..2758670 (-)	261	WP_014937088.1	hypothetical protein	-
ACE4RH_RS14085	-	2759052..2759165 (-)	114	WP_014937089.1	hypothetical protein	-
ACE4RH_RS14090	-	2759832..2761832 (-)	2001	WP_000776741.1	ABC transporter permease	-
ACE4RH_RS14095	-	2761829..2762584 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACE4RH_RS14100	braS	2762692..2763579 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACE4RH_RS14105	braR	2763590..2764255 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACE4RH_RS14110	-	2764281..2764481 (-)	201	WP_000604731.1	hypothetical protein	-
ACE4RH_RS14115	-	2764679..2766103 (+)	1425	WP_000953736.1	alkaline phosphatase	-
ACE4RH_RS14120	-	2766163..2766264 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACE4RH_RS14125	-	2766386..2766841 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACE4RH_RS14130	-	2767086..2767847 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1165403 ACE4RH_RS14100 WP_000143420.1 2762692..2763579(-) (braS) [Staphylococcus aureus isolate E3_22S00626-1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1165403 ACE4RH_RS14100 WP_000143420.1 2762692..2763579(-) (braS) [Staphylococcus aureus isolate E3_22S00626-1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTGGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993