Detailed information NTG1139552

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: DQM87_RS00805
• Genome accession: NZ_LS483384
• Coordinates: 118894..119328 (+)
• Length: 144 a.a.
• NCBI ID: WP_023612536.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC13743
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 113894..124328

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM87_RS00775 (NCTC13743_00156)	-	115563..115928 (+)	366	WP_002986560.1	DUF1033 family protein	-
DQM87_RS00780 (NCTC13743_00157)	comYA	116021..116959 (+)	939	WP_111704879.1	competence type IV pilus ATPase ComGA	Machinery gene
DQM87_RS00785 (NCTC13743_00158)	comYB	116895..117929 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQM87_RS00790 (NCTC13743_00159)	comYC	117931..118257 (+)	327	WP_032465607.1	competence type IV pilus major pilin ComGC	Machinery gene
DQM87_RS00795 (NCTC13743_00160)	comGD	118232..118660 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
DQM87_RS00800 (NCTC13743_00161)	comGE	118617..118901 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
DQM87_RS00805 (NCTC13743_00162)	comYF	118894..119328 (+)	435	WP_023612536.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQM87_RS00810 (NCTC13743_00163)	comGG	119312..119638 (+)	327	WP_002992739.1	competence type IV pilus minor pilin ComGG	-
DQM87_RS00815 (NCTC13743_00164)	comYH	119736..120689 (+)	954	WP_002987790.1	class I SAM-dependent methyltransferase	Machinery gene
DQM87_RS00820 (NCTC13743_00165)	-	120748..121944 (+)	1197	WP_023612537.1	acetate kinase	-
DQM87_RS00825	-	122131..122439 (+)	309	WP_030126458.1	hypothetical protein	-
DQM87_RS00830 (NCTC13743_00166)	proC	122522..123292 (-)	771	WP_002986527.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16688.29 Da
• Isoelectric Point: 10.2526

>NTDB_id=1139552 DQM87_RS00805 WP_023612536.1 118894..119328(+) (comYF) [Streptococcus pyogenes strain NCTC13743]
MSKQLSNIKAFTFLEALIALLVISGSLLVYQGLTRTLLKHSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1139552 DQM87_RS00805 WP_023612536.1 118894..119328(+) (comYF) [Streptococcus pyogenes strain NCTC13743]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCTTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCGAACCCTCCTTAAACATAGCCATTATCTAGCCCGTCATGATCAAGATAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	50.36	96.528	0.486
comYF	Streptococcus mutans UA159	49.64	96.528	0.479
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	93.056	0.403
comGF/cglF	Streptococcus pneumoniae Rx1	42.105	92.361	0.389
comGF/cglF	Streptococcus pneumoniae D39	42.105	92.361	0.389
comGF/cglF	Streptococcus pneumoniae R6	42.105	92.361	0.389
comGF/cglF	Streptococcus pneumoniae TIGR4	42.105	92.361	0.389
comGF/cglF	Streptococcus mitis SK321	41.353	92.361	0.382