Detailed information NTG1138095

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL39_RS03885
• Genome accession: NZ_LS483353
• Coordinates: 738528..739364 (-)
• Length: 278 a.a.
• NCBI ID: WP_030127252.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC4001
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 733528..744364

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL39_RS03875 (NCTC4001_00779)	trmFO	734811..736157 (-)	1347	WP_021340038.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
DQL39_RS03880 (NCTC4001_00780)	topA	736292..738421 (-)	2130	WP_011017773.1	type I DNA topoisomerase	-
DQL39_RS03885 (NCTC4001_00781)	dprA	738528..739364 (-)	837	WP_030127252.1	DNA-processing protein DprA	Machinery gene
DQL39_RS03890 (NCTC4001_00782)	-	739429..740220 (-)	792	WP_111718069.1	ribonuclease HII	-
DQL39_RS03895 (NCTC4001_00783)	ylqF	740210..741058 (-)	849	WP_038433405.1	ribosome biogenesis GTPase YlqF	-
DQL39_RS03900 (NCTC4001_00784)	-	741277..741717 (+)	441	WP_011017769.1	DUF1836 domain-containing protein	-
DQL39_RS03905 (NCTC4001_00785)	trhA	741714..742364 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQL39_RS03910 (NCTC4001_00786)	-	742481..743392 (+)	912	WP_038433406.1	diacylglycerol/lipid kinase family protein	-
DQL39_RS03915 (NCTC4001_00787)	-	743442..743876 (-)	435	WP_038433407.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31087.09 Da
• Isoelectric Point: 9.2565

>NTDB_id=1138095 DQL39_RS03885 WP_030127252.1 738528..739364(-) (dprA) [Streptococcus pyogenes strain NCTC4001]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSNTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1138095 DQL39_RS03885 WP_030127252.1 738528..739364(-) (dprA) [Streptococcus pyogenes strain NCTC4001]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTTGGCTCCAGACGCTCAAGCAATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367