Detailed information NTG1127865

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: FGL21_RS06090
• Genome accession: NZ_LR594047
• Coordinates: 1185647..1186321 (-)
• Length: 224 a.a.
• NCBI ID: WP_014612304.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC11554
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 1180647..1191321

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL21_RS06065 (NCTC11554_01244)	-	1180832..1182109 (-)	1278	WP_014612301.1	pyrimidine-nucleoside phosphorylase	-
FGL21_RS06070 (NCTC11554_01245)	-	1182096..1182695 (-)	600	WP_138128085.1	class I SAM-dependent methyltransferase	-
FGL21_RS06075 (NCTC11554_01246)	coaA	1182964..1183884 (+)	921	WP_003058858.1	type I pantothenate kinase	-
FGL21_RS06080 (NCTC11554_01247)	rpsT	1183938..1184186 (+)	249	WP_009881183.1	30S ribosomal protein S20	-
FGL21_RS06085 (NCTC11554_01248)	ciaH	1184344..1185654 (-)	1311	WP_014612303.1	HAMP domain-containing sensor histidine kinase	Regulator
FGL21_RS06090 (NCTC11554_01249)	ciaR	1185647..1186321 (-)	675	WP_014612304.1	response regulator transcription factor	Regulator
FGL21_RS06095 (NCTC11554_01250)	-	1186525..1189062 (-)	2538	WP_014612305.1	M1 family metallopeptidase	-
FGL21_RS06100 (NCTC11554_01251)	phoU	1189263..1189916 (-)	654	WP_003057760.1	phosphate signaling complex protein PhoU	-
FGL21_RS06105 (NCTC11554_01252)	pstB	1189994..1190752 (-)	759	WP_003057749.1	phosphate ABC transporter ATP-binding protein PstB	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25592.57 Da
• Isoelectric Point: 4.4128

>NTDB_id=1127865 FGL21_RS06090 WP_014612304.1 1185647..1186321(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11554]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESLDDKGQGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLAFGNVVVDLGQKEVQVDGRPIELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFVDKLQTLRSVGYILKSHE

Nucleotide

• Length: 675 bp

>NTDB_id=1127865 FGL21_RS06090 WP_014612304.1 1185647..1186321(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11554]
ATGATCAAACTATTATTAGTAGAAGATGACTTAAGTTTATCCAATTCCATTTTCGATTTTTTGGATGATTTTGCTGATGT
CACACAAGTTTTTGATGGCGATGAAGGCTTATATGAAGCCGAAAGTGGCATTTACGATTTGATTTTACTTGACCTTATGT
TGCCAGAAAAAAATGGCTTCCAAGTCTTGAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTGTTGATTATGACAGCC
AAAGAAAGTCTAGATGATAAGGGACAGGGCTTTGAATTAGGAGCAGATGATTACCTCACTAAGCCTTTTTACCTGGAGGA
ACTCAAGATGCGAATTCAAGCCCTGTTAAAACGTACAGGGAAATTCACGGATAAAAATCTAGCCTTTGGGAATGTCGTAG
TGGATTTAGGACAAAAAGAAGTTCAAGTGGATGGCCGGCCGATAGAACTATTAGGTAAAGAGTTTGATTTGTTGGTCTAC
CTGTTACAAAATCAGAATGTTATTTTACCTAAAACACAAATTTTTGATCGCTTATGGGGTTTTGATAGCGATACGACCAT
TTCAGTAGTTGAAGTTTACGTTTCTAAAATTAGAAAAAAACTGAAAGGTACAGATTTTGTGGACAAACTGCAGACATTGA
GAAGCGTGGGGTATATTCTAAAAAGCCATGAATAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

• Response regulator receiver domain (Response_reg) (5-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	84.163	98.661	0.83
ciaR	Streptococcus pneumoniae D39	84.163	98.661	0.83
ciaR	Streptococcus pneumoniae R6	84.163	98.661	0.83
ciaR	Streptococcus pneumoniae TIGR4	84.163	98.661	0.83
ciaR	Streptococcus mutans UA159	83.71	98.661	0.826
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.326	100	0.388
vicR	Streptococcus mutans UA159	35.443	100	0.375