Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   FGL18_RS00720 Genome accession   NZ_LR594046
Coordinates   117563..118504 (+) Length   313 a.a.
NCBI ID   WP_138124405.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain NCTC6403     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 112563..123504
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL18_RS00710 (NCTC6403_00144) rpoC 113224..116865 (+) 3642 WP_111714766.1 DNA-directed RNA polymerase subunit beta' -
  FGL18_RS00715 (NCTC6403_00145) - 117069..117434 (+) 366 WP_003055257.1 DUF1033 family protein -
  FGL18_RS00720 (NCTC6403_00146) comYA 117563..118504 (+) 942 WP_138124405.1 competence type IV pilus ATPase ComGA Machinery gene
  FGL18_RS00725 (NCTC6403_00147) comYB 118440..119471 (+) 1032 WP_138126921.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGL18_RS00730 (NCTC6403_00148) comYC 119473..119799 (+) 327 WP_138124408.1 competence type IV pilus major pilin ComGC Machinery gene
  FGL18_RS00735 (NCTC6403_00149) comGD 119774..120202 (+) 429 WP_256867133.1 competence type IV pilus minor pilin ComGD -
  FGL18_RS00740 (NCTC6403_00150) comGE 120210..120455 (+) 246 WP_242002881.1 competence type IV pilus minor pilin ComGE -
  FGL18_RS00745 (NCTC6403_00151) comGF 120436..120876 (+) 441 WP_138124417.1 competence type IV pilus minor pilin ComGF -
  FGL18_RS00750 (NCTC6403_00152) comGG 120854..121228 (+) 375 WP_138124420.1 competence type IV pilus minor pilin ComGG -
  FGL18_RS00755 (NCTC6403_00153) comYH 121291..122244 (+) 954 WP_138124423.1 class I SAM-dependent methyltransferase Machinery gene
  FGL18_RS00760 (NCTC6403_00154) - 122303..123499 (+) 1197 WP_084916957.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35230.36 Da        Isoelectric Point: 7.0192

>NTDB_id=1127773 FGL18_RS00720 WP_138124405.1 117563..118504(+) (comYA) [Streptococcus dysgalactiae strain NCTC6403]
MVQALARSILKEAEQIQAQDIYILPKEDQYELLIRVGDERRLVDVYRGDRMAHLISHFKFVAGMTVGEKRRCQVGSCDYD
IGEDTLLSLRLSSVGNYRGQESLVIRLLHHQQRSLHYWFDGLKTVARQIGGRGLYLFAGPVGSGKTTLMHQLIADYYQGA
QVISIEDPVEIKNHQALQLQVNDSIGMTYDNLIKLSLRHRPDILIIGEIRDSQTARAVIRASLTGVLVFSTVHAKSISGV
YARLLELGVTRAELDNCLALVAYQRLLNGGALIDSTQTEFEHYSPNQWNQKIDDLLAAGYLSPEQARLEKIIQ

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1127773 FGL18_RS00720 WP_138124405.1 117563..118504(+) (comYA) [Streptococcus dysgalactiae strain NCTC6403]
ATGGTACAAGCATTAGCAAGATCTATTTTGAAAGAAGCTGAGCAGATTCAAGCTCAAGATATCTATATTTTGCCAAAGGA
AGATCAGTATGAGCTATTGATAAGGGTAGGAGATGAAAGGAGATTGGTGGATGTTTATCGGGGCGATCGGATGGCTCATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGACCGTTGGTGAGAAACGACGCTGTCAAGTCGGTTCTTGTGATTATGAT
ATCGGTGAAGACACACTTTTGTCTCTACGCCTGTCTAGTGTTGGAAATTACCGTGGACAAGAGAGCCTAGTGATTCGGTT
ATTACATCATCAACAAAGAAGTTTACATTACTGGTTTGACGGACTGAAAACAGTTGCACGTCAGATTGGAGGCCGAGGAC
TCTATCTTTTTGCAGGTCCAGTCGGATCAGGCAAAACGACTTTGATGCACCAATTGATTGCTGATTATTATCAGGGAGCA
CAGGTCATTAGCATAGAAGATCCGGTGGAAATTAAAAATCATCAAGCGCTCCAATTACAAGTTAATGATAGTATTGGCAT
GACTTACGACAACTTGATCAAACTATCTTTACGGCATCGCCCTGATATTTTAATCATTGGTGAAATTCGAGACAGCCAGA
CAGCTAGAGCGGTTATTAGAGCAAGTTTAACAGGTGTCTTAGTATTTTCAACAGTTCATGCCAAAAGCATTTCTGGTGTT
TATGCCAGATTACTAGAACTAGGAGTGACAAGAGCAGAATTAGACAATTGTTTGGCTTTGGTTGCTTACCAACGATTGCT
TAATGGAGGAGCATTGATTGACTCAACTCAAACAGAATTTGAACACTACTCACCAAACCAATGGAATCAGAAAATTGATG
ACCTTCTTGCAGCGGGATATCTCAGTCCGGAGCAAGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

62.058

99.361

0.617
  comYA Streptococcus mutans UA159

62.058

99.361

0.617
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.613

99.042

0.61
  comYA Streptococcus gordonii str. Challis substr. CH1

60.772

99.361

0.604
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.807

99.361

0.594
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae D39

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae R6

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

59.486

99.361

0.591
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

38.908

93.61

0.364

Multiple sequence alignment