Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FGL00_RS01735 Genome accession   NZ_LR594034
Coordinates   325938..326699 (+) Length   253 a.a.
NCBI ID   WP_003059809.1    Uniprot ID   A0A9X5LVZ2
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 320938..331699
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL00_RS01720 (NCTC8546_00356) - 321197..322765 (-) 1569 WP_138098236.1 ABC transporter substrate-binding protein/permease -
  FGL00_RS01725 (NCTC8546_00357) - 322964..324889 (+) 1926 WP_046159713.1 DUF2207 domain-containing protein -
  FGL00_RS01730 (NCTC8546_00358) - 324955..325794 (+) 840 WP_015057324.1 undecaprenyl-diphosphate phosphatase -
  FGL00_RS01735 (NCTC8546_00359) mecA 325938..326699 (+) 762 WP_003059809.1 adaptor protein MecA Regulator
  FGL00_RS01740 (NCTC8546_00360) - 326706..327875 (+) 1170 WP_003054822.1 MraY family glycosyltransferase -
  FGL00_RS01745 (NCTC8546_00361) sufC 327988..328758 (+) 771 WP_003061584.1 Fe-S cluster assembly ATPase SufC -
  FGL00_RS01750 (NCTC8546_00362) sufD 328855..330117 (+) 1263 WP_138083695.1 Fe-S cluster assembly protein SufD -
  FGL00_RS01755 (NCTC8546_00363) - 330148..331374 (+) 1227 WP_065957336.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29071.72 Da        Isoelectric Point: 4.0755

>NTDB_id=1127224 FGL00_RS01735 WP_003059809.1 325938..326699(+) (mecA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKDLNLEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEMMEDVVEATLASQTEETAEEVGQEPELLDYVH
YVLDFATLSEAVAFSQTIDFPVEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEHASPGTKTRAYLQEHGVQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=1127224 FGL00_RS01735 WP_003059809.1 325938..326699(+) (mecA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGGATGGAATT
AAAAGATTTCCTCATTCCTCAAGAAAAAACGGAAGAGTTCTTCTACTCTGTCATGGATGAGTTGGACCTACCAGACAATT
TCAAAGATAGTGGCATGCTTAGCTTTCGTGTGACCCCTAGAAAAGACCGTTTGGATGTCTTTGTAACCAAGTCTGAACTC
AATAAGGACCTTAATCTTGAAGATTTAGCTGACTTGGGAGATATCTCTCAAATGACTCCTGAAGACTTTTTCAAGAGCTT
GGAACAATCTATGCGAGAAAAAGGGGATGTTAATGCCCATGAGAAACTGGAAAAAATTGAAGAAATGATGGAAGATGTTG
TCGAAGCCACTCTAGCTAGTCAAACGGAAGAGACCGCTGAGGAAGTGGGTCAAGAACCAGAGCTGTTAGATTACGTGCAT
TATGTTTTGGACTTTGCAACACTTTCAGAGGCCGTCGCTTTTTCTCAGACAATTGATTTTCCTGTTGAAGCTTCAGAATT
GTACAAAGGTGACAGCCGTTATCATATGACGATTTTATTAGATGTTCAGCAGCAACCATCTTATTTTGCCAATGTGATGT
ATGCAAGACTGATTGAGCATGCTAGTCCTGGAACAAAAACCAGAGCTTACTTACAAGAGCATGGCGTACAATTGATTTTG
GATGGGGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.8

98.814

0.64
  mecA Streptococcus thermophilus LMD-9

57.43

98.419

0.565
  mecA Streptococcus thermophilus LMG 18311

56.627

98.419

0.557
  mecA Streptococcus pneumoniae Rx1

47.843

100

0.482
  mecA Streptococcus pneumoniae D39

47.843

100

0.482
  mecA Streptococcus pneumoniae R6

47.843

100

0.482
  mecA Streptococcus pneumoniae TIGR4

47.843

100

0.482

Multiple sequence alignment