Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   FGK95_RS00370 Genome accession   NZ_LR590625
Coordinates   56174..57085 (+) Length   303 a.a.
NCBI ID   WP_093999213.1    Uniprot ID   -
Organism   Streptococcus canis strain B700072     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 51174..62085
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK95_RS00355 (SAMEA5186854_00071) purE 52669..53160 (+) 492 WP_093999210.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  FGK95_RS00360 (SAMEA5186854_00072) purK 53147..54217 (+) 1071 WP_093999211.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  FGK95_RS00365 (SAMEA5186854_00073) purB 54744..56036 (+) 1293 WP_093999212.1 adenylosuccinate lyase -
  FGK95_RS00370 (SAMEA5186854_00074) comR 56174..57085 (+) 912 WP_093999213.1 transcriptional regulator Rgg4/ComR Regulator
  FGK95_RS11100 (SAMEA5186854_00075) comS 57174..57269 (+) 96 WP_205407142.1 quorum-sensing system DWW-type pheromone Regulator
  FGK95_RS00375 (SAMEA5186854_00076) ruvB 57312..58310 (+) 999 WP_093999214.1 Holliday junction branch migration DNA helicase RuvB -
  FGK95_RS00380 (SAMEA5186854_00077) - 58451..58894 (+) 444 WP_093999215.1 low molecular weight protein-tyrosine-phosphatase -
  FGK95_RS00385 (SAMEA5186854_00078) - 58911..59312 (+) 402 WP_093999216.1 MORN repeat-containing protein -
  FGK95_RS00390 (SAMEA5186854_00079) - 59309..61084 (+) 1776 WP_093999217.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35696.92 Da        Isoelectric Point: 4.5316

>NTDB_id=1127080 FGK95_RS00370 WP_093999213.1 56174..57085(+) (comR) [Streptococcus canis strain B700072]
MLEHFGEKVKGLRQEKKISREDLCGDESELSVRQLARIELSQSIPSLAKVIFIAKALDVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDGKLQVREEQFDEIFEDYYDQLPEEEQLIIDCLQATLDTLLSENINFGVDLLQEYFKQTKAKSHFKQND
LILIELYLAYLDIEGMNGQYSDKKFYDSLLDNLLKQFENFELDELFIVNKIIIDISSLSIKSNQLDNLEKTIEMSQRIMA
KIQDWNRMPILKLIEWKYFLIKQNDKQKAEESFTKACLFAQVTGDQYLEKQLIKEWEKDNKSY

Nucleotide


Download         Length: 912 bp        

>NTDB_id=1127080 FGK95_RS00370 WP_093999213.1 56174..57085(+) (comR) [Streptococcus canis strain B700072]
ATGTTAGAGCATTTTGGTGAAAAAGTGAAAGGGCTAAGACAAGAGAAAAAGATTAGCAGAGAAGACTTATGTGGGGATGA
GTCTGAATTATCTGTTCGTCAACTAGCGAGGATTGAGTTGAGCCAGTCTATACCAAGTTTAGCCAAGGTTATTTTTATTG
CAAAAGCCTTAGATGTTAGCGTAGGTTATTTGACTGATGGGGCCAACCTTGAGTTACCCAAACGTTACAAAGAGTTAAAA
TATTTAATTTTGCGGACGCCAACTTATATGGATGATGGCAAATTACAAGTTCGAGAAGAACAGTTTGATGAGATATTTGA
GGATTACTATGACCAGCTGCCTGAGGAGGAGCAATTAATTATTGATTGCTTACAAGCAACCCTAGATACTTTATTAAGTG
AAAATATTAATTTTGGTGTTGATTTGTTACAAGAGTACTTTAAACAGACTAAGGCTAAGTCACATTTTAAACAAAACGAC
TTGATACTTATCGAGTTGTATTTGGCCTATCTTGACATAGAAGGAATGAACGGTCAATATTCGGATAAAAAATTCTATGA
TTCTCTGCTGGATAATCTTTTAAAACAATTTGAAAATTTTGAGTTAGATGAATTATTTATAGTCAATAAAATCATTATTG
ATATTTCTTCATTAAGTATTAAATCTAATCAACTTGATAATTTAGAAAAAACAATTGAAATGAGTCAGAGAATTATGGCA
AAAATTCAGGATTGGAACAGGATGCCCATATTAAAATTAATAGAGTGGAAATATTTCTTAATCAAACAAAATGACAAGCA
AAAGGCAGAAGAATCATTTACAAAAGCCTGTTTATTTGCTCAAGTAACAGGTGATCAATATTTAGAGAAACAGCTGATTA
AAGAATGGGAAAAAGATAACAAAAGCTATTAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-296)

Helix-turn-helix (HTH_3)

(12-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

86.469

100

0.865
  comR Streptococcus pyogenes MGAS315

57.191

98.68

0.564
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

51.211

95.38

0.488
  comR Streptococcus mutans UA159

47.02

99.67

0.469

Multiple sequence alignment