Detailed information NTG1126883

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: FGK94_RS06030
• Genome accession: NZ_LR590471
• Coordinates: 1294428..1295342 (-)
• Length: 304 a.a.
• NCBI ID: WP_043029238.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC11854
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1289428..1300342

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK94_RS06010 (NCTC11854_01232)	-	1290321..1292102 (-)	1782	WP_043029239.1	acyltransferase family protein	-
FGK94_RS06015 (NCTC11854_01233)	-	1292099..1292500 (-)	402	WP_012514718.1	MORN repeat-containing protein	-
FGK94_RS06020 (NCTC11854_01234)	-	1292506..1292964 (-)	459	WP_012678781.1	low molecular weight protein-tyrosine-phosphatase	-
FGK94_RS06025 (NCTC11854_01235)	ruvB	1293212..1294213 (-)	1002	WP_042669757.1	Holliday junction branch migration DNA helicase RuvB	-
FGK94_RS10495 (NCTC11854_01236)	comS	1294247..1294345 (-)	99	WP_021320241.1	quorum-sensing system DWW-type pheromone	Regulator
FGK94_RS06030 (NCTC11854_01237)	comR	1294428..1295342 (-)	915	WP_043029238.1	helix-turn-helix domain-containing protein	Regulator
FGK94_RS06035 (NCTC11854_01238)	purB	1295640..1296932 (-)	1293	WP_043029241.1	adenylosuccinate lyase	-
FGK94_RS06040 (NCTC11854_01239)	-	1297529..1297753 (-)	225	WP_043029237.1	hypothetical protein	-
FGK94_RS06045 (NCTC11854_01240)	purK	1297768..1298841 (-)	1074	WP_043029236.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
FGK94_RS06050 (NCTC11854_01241)	purE	1298828..1299316 (-)	489	WP_021320238.1	5-(carboxyamino)imidazole ribonucleotide mutase	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35834.44 Da
• Isoelectric Point: 4.5517

>NTDB_id=1126883 FGK94_RS06030 WP_043029238.1 1294428..1295342(-) (comR) [Streptococcus equi subsp. zooepidemicus strain NCTC11854]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVFIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIVGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKLEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDIEMAKKCYDKACLFAQLTGDQYLEKKLREEWGKDIKRYQ

Nucleotide

• Length: 915 bp

>NTDB_id=1126883 FGK94_RS06030 WP_043029238.1 1294428..1295342(-) (comR) [Streptococcus equi subsp. zooepidemicus strain NCTC11854]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTTCGGTATCAGAAAAAAATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTGGCACGAATAGAACTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTTTATTG
CTAAGGCTTTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTACCGAAGCGCTATAAGGAGCTTAAA
TATTTGATTTTAAGAACACCGACCTATATGGACGATGACAAATTAAAGCTACGTGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGATCAGCTGCCAGAGGAAGAAAAGCTTGTGGTGGACTGCTTGCAGTCCATAATGGATACGTTATTAACTG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAGACAAAAAGCAAGACTCAATTTAGAGAGAATGAC
CTTATTCTTATTGAGCTGTATTTAGCGTATCTGGATATTGTGGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTATTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATCGTCAATAAAATAGCTATAG
GGATTTCCTCGTTGAGCATCAAAAACAATAAGCTGGAGATTCTTGAGAAGGTTATTGTGCTTAGTCAAAAAATTATCCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATATGCTCTAATGAAGAAAAAAGATATAGA
AATGGCCAAAAAATGCTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTGGAAAAGAAATTGAGAG
AAGAATGGGGTAAAGATATAAAACGATATCAATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix domain (HTH_19) (6-69)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.917	99.671	0.747
comR	Streptococcus pyogenes MGAS315	54.817	99.013	0.543
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.724	95.395	0.493
comR	Streptococcus mutans UA159	49.164	98.355	0.484
comR	Streptococcus suis P1/7	38.255	98.026	0.375
comR	Streptococcus suis 05ZYH33	38.305	97.039	0.372