Detailed information NTG1126283

Bioinformatically predicted

Overview

• Name: comX/comX2
• Type: Regulator
• Locus tag: E0F31_RS09270
• Genome accession: NZ_LR216064
• Coordinates: 1732430..1732909 (-)
• Length: 159 a.a.
• NCBI ID: WP_000588897.1
• Uniprot ID: Q9R2W8
• Organism: Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1727430..1737909

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F31_RS09270 (SAMEA3714520_01745)	comX/comX2	1732430..1732909 (-)	480	WP_000588897.1	sigma-70 family RNA polymerase sigma factor	Regulator
E0F31_RS09280 (SAMEA3714520_01747)	rlmD	1733179..1734534 (-)	1356	WP_001050309.1	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	-
E0F31_RS09285 (SAMEA3714520_01748)	recX	1734572..1735348 (+)	777	WP_050206536.1	recombination regulator RecX	-
E0F31_RS09290 (SAMEA3714520_01749)	-	1735437..1735970 (+)	534	WP_000775321.1	DUF402 domain-containing protein	-
E0F31_RS11380 (SAMEA3714520_01750)	-	1736328..1736534 (-)	207	WP_000775827.1	transcriptional regulator	-

Sequence

Protein

• Length: 159 a.a.
• Molecular weight: 19873.52 Da
• Isoelectric Point: 7.3797

>NTDB_id=1126283 E0F31_RS09270 WP_000588897.1 1732430..1732909(-) (comX/comX2) [Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH

Nucleotide

• Length: 480 bp

>NTDB_id=1126283 E0F31_RS09270 WP_000588897.1 1732430..1732909(-) (comX/comX2) [Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
ATCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGAGAGATCAGTCATCGTATAAGTGAGGGAGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG

Domains

No domain identified.

3D structure

• AlphaFold DB: Q9R2W8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/comX2	Streptococcus pneumoniae Rx1	100	100	1
comX/comX1	Streptococcus pneumoniae Rx1	100	100	1
comX/comX2	Streptococcus pneumoniae D39	100	100	1
comX/comX1	Streptococcus pneumoniae D39	100	100	1
comX/comX2	Streptococcus pneumoniae R6	100	100	1
comX/comX1	Streptococcus pneumoniae R6	100	100	1
comX/comX2	Streptococcus pneumoniae TIGR4	99.371	100	0.994
comX/comX1	Streptococcus pneumoniae TIGR4	99.371	100	0.994
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	92.453	100	0.925
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	92.453	100	0.925
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	90.566	100	0.906
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	89.241	99.371	0.887
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	48.718	98.113	0.478
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	48.718	98.113	0.478
comX/sigX	Streptococcus mutans UA159	46	94.34	0.434
comX/sigX	Streptococcus suis isolate S10	45.695	94.969	0.434
comX/sigX	Streptococcus suis D9	45.695	94.969	0.434
comX/sigX	Streptococcus suis P1/7	45.695	94.969	0.434
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	39.216	96.226	0.377
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	39.216	96.226	0.377
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	40	94.34	0.377
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	40	94.34	0.377
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	40	94.34	0.377
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	40	94.34	0.377