Detailed information NTG1122233

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: EL177_RS12710
• Genome accession: NZ_LR134358
• Coordinates: 2117457..2118317 (-)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain NCTC13484
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2112457..2123317

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL177_RS12665 (NCTC13484_02179)	rplU	2112570..2112878 (-)	309	WP_003691838.1	50S ribosomal protein L21	-
EL177_RS12675 (NCTC13484_02180)	-	2113102..2114076 (+)	975	WP_003689819.1	polyprenyl synthetase family protein	-
EL177_RS12680 (NCTC13484_02181)	-	2114080..2114526 (+)	447	WP_003689818.1	DUF441 domain-containing protein	-
EL177_RS12695 (NCTC13484_02183)	pilF	2114864..2116540 (+)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
EL177_RS12700 (NCTC13484_02184)	-	2116626..2116835 (-)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
EL177_RS12705 (NCTC13484_02185)	coaE	2116828..2117460 (-)	633	WP_003689816.1	dephospho-CoA kinase	-
EL177_RS12710 (NCTC13484_02186)	pilD	2117457..2118317 (-)	861	WP_003689814.1	prepilin peptidase	Machinery gene
EL177_RS12715 (NCTC13484_02187)	pilG	2118391..2119623 (-)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
EL177_RS12725 (NCTC13484_02188)	pgi	2120133..2121776 (+)	1644	WP_003689806.1	glucose-6-phosphate isomerase	-
EL177_RS12730 (NCTC13484_02189)	dapD	2121986..2122807 (+)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=1122233 EL177_RS12710 WP_003689814.1 2117457..2118317(-) (pilD) [Neisseria gonorrhoeae strain NCTC13484]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=1122233 EL177_RS12710 WP_003689814.1 2117457..2118317(-) (pilD) [Neisseria gonorrhoeae strain NCTC13484]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441