Detailed information NTG1122010

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: EL147_RS05720
• Genome accession: NZ_LR134341
• Coordinates: 1185199..1186104 (-)
• Length: 301 a.a.
• NCBI ID: WP_007891754.1
• Uniprot ID: G5KAF4
• Organism: Streptococcus pseudoporcinus strain NCTC13786
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1180199..1191104

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL147_RS05700 (NCTC13786_01140)	-	1180900..1182678 (-)	1779	WP_007896538.1	acyltransferase family protein	-
EL147_RS05705 (NCTC13786_01141)	-	1182675..1183076 (-)	402	WP_007891657.1	membrane protein	-
EL147_RS05710 (NCTC13786_01142)	-	1183085..1183528 (-)	444	WP_007891874.1	low molecular weight protein-tyrosine-phosphatase	-
EL147_RS05715 (NCTC13786_01143)	ruvB	1183998..1184996 (-)	999	WP_007891873.1	Holliday junction branch migration DNA helicase RuvB	-
EL147_RS10720 (NCTC13786_01144)	-	1185028..1185126 (-)	99	WP_198920371.1	quorum-sensing system DWW-type pheromone	-
EL147_RS05720 (NCTC13786_01145)	comR	1185199..1186104 (-)	906	WP_007891754.1	helix-turn-helix transcriptional regulator	Regulator
EL147_RS05725 (NCTC13786_01146)	purB	1186207..1187499 (-)	1293	WP_007891752.1	adenylosuccinate lyase	-
EL147_RS05730 (NCTC13786_01147)	-	1187538..1187966 (-)	429	WP_007892002.1	GNAT family N-acetyltransferase	-
EL147_RS10825	-	1187930..1188154 (-)	225	WP_162097551.1	hypothetical protein	-
EL147_RS05735 (NCTC13786_01148)	-	1189115..1189732 (+)	618	WP_007891751.1	hypothetical protein	-
EL147_RS05740 (NCTC13786_01149)	-	1189853..1190944 (+)	1092	WP_007891648.1	CHAP domain-containing protein	-

Sequence

Protein

• Length: 301 a.a.
• Molecular weight: 35913.80 Da
• Isoelectric Point: 8.2451

>NTDB_id=1122010 EL147_RS05720 WP_007891754.1 1185199..1186104(-) (comR) [Streptococcus pseudoporcinus strain NCTC13786]
MKKLGKKIQKLRLDKSLTRETICGDESELSIRQLARIEKGQSIPSLSKVLFIAKKLDLPVIELINPECLVLPKRYKELKY
LILRRPTYMNDQNLVDREAQFDEIFEDYYATLPEEEQLIIDLLQSRFDVYQSGDTNYGKELLREYISQIRKKKSYALNDI
FLIDLYLTCGMVSNFKEELFDKGNFDCFTNKLVLLEDKLELKDLFLLNNVLLTSIAVGISIKEYQKTRILLDVCRRIMTI
TQDFQRMPIYYMYEWKYTLFYMKDSQKAYYYYRQSLIFARTLTDSYLVNRLKTSWELDNQS

Nucleotide

• Length: 906 bp

>NTDB_id=1122010 EL147_RS05720 WP_007891754.1 1185199..1186104(-) (comR) [Streptococcus pseudoporcinus strain NCTC13786]
ATGAAAAAACTTGGGAAAAAGATTCAAAAATTGAGGTTAGACAAGAGCCTGACTCGTGAAACGATTTGTGGAGATGAGTC
AGAATTATCAATTCGACAGCTAGCTCGTATTGAAAAAGGGCAATCTATTCCTAGTTTATCTAAAGTCTTATTTATTGCGA
AAAAATTAGATTTACCTGTTATTGAACTTATTAATCCAGAATGTTTGGTTCTACCAAAACGTTATAAGGAACTTAAATAT
TTGATTCTTAGGCGACCAACCTACATGAATGATCAAAATTTAGTGGATCGCGAAGCTCAGTTTGATGAAATATTTGAAGA
TTATTACGCGACTTTACCTGAAGAAGAGCAGCTAATTATTGATTTATTACAGTCTCGGTTTGATGTCTACCAAAGTGGTG
ATACTAATTATGGTAAAGAATTACTCCGTGAATATATCAGCCAAATTCGTAAGAAAAAGAGTTACGCTTTAAATGATATT
TTTTTAATCGATCTTTACTTAACTTGTGGAATGGTTTCAAATTTCAAAGAAGAATTATTTGATAAGGGAAATTTTGATTG
TTTTACTAATAAATTAGTCCTTTTGGAAGATAAGTTAGAGTTAAAAGATCTCTTTTTACTAAACAACGTCCTTCTCACTT
CCATTGCCGTAGGGATTAGTATTAAAGAATATCAGAAAACAAGGATACTTTTGGATGTTTGTCGACGGATTATGACGATT
ACCCAAGACTTTCAGCGTATGCCTATTTACTATATGTACGAATGGAAATACACTTTATTTTATATGAAGGACTCCCAAAA
GGCTTATTATTACTATCGTCAATCCTTAATATTTGCACGGACACTAACAGATAGTTATCTTGTTAATCGTTTAAAAACAA
GTTGGGAATTAGATAATCAATCGTAA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (72-295)

3D structure

• AlphaFold DB: G5KAF4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	50.671	99.003	0.502
comR	Streptococcus pyogenes MGAS8232	45.847	100	0.458
comR	Streptococcus mutans UA159	44.186	100	0.442
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	45.172	96.346	0.435
comR	Streptococcus suis P1/7	38.411	100	0.385
comR	Streptococcus suis 05ZYH33	38.411	100	0.385