Detailed information NTG1120029

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: EL079_RS05275
• Genome accession: NZ_LR134283
• Coordinates: 1087095..1087769 (+)
• Length: 224 a.a.
• NCBI ID: WP_018543646.1
• Uniprot ID: A0A448AIB9
• Organism: Streptococcus anginosus strain NCTC10713
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1082095..1092769

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL079_RS05245 (NCTC10713_01095)	-	1082428..1082712 (-)	285	WP_003025714.1	DUF3165 family protein	-
EL079_RS05250 (NCTC10713_01096)	typA	1082777..1084618 (-)	1842	WP_003032385.1	translational GTPase TypA	-
EL079_RS05255 (NCTC10713_01097)	-	1084796..1085521 (+)	726	WP_003032391.1	pseudouridine synthase	-
EL079_RS05260 (NCTC10713_01098)	-	1085542..1085922 (-)	381	WP_018543647.1	rhodanese-like domain-containing protein	-
EL079_RS05265 (NCTC10713_01099)	-	1085916..1086140 (-)	225	WP_003025724.1	YqgQ family protein	-
EL079_RS05270 (NCTC10713_01100)	-	1086414..1086941 (-)	528	WP_003032411.1	Dps family protein	-
EL079_RS05275 (NCTC10713_01101)	cclA/cilC	1087095..1087769 (+)	675	WP_018543646.1	A24 family peptidase	Machinery gene
EL079_RS05280 (NCTC10713_01102)	-	1087764..1088282 (-)	519	WP_003032357.1	VanZ family protein	-
EL079_RS05285 (NCTC10713_01103)	rlmN	1088275..1089357 (-)	1083	WP_018543645.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
EL079_RS05290 (NCTC10713_01104)	-	1089391..1089954 (-)	564	WP_026248195.1	YutD family protein	-
EL079_RS05295 (NCTC10713_01105)	sepM	1090094..1091149 (-)	1056	WP_003032358.1	SepM family pheromone-processing serine protease	Regulator
EL079_RS05300 (NCTC10713_01106)	coaD	1091130..1091627 (-)	498	WP_003032432.1	pantetheine-phosphate adenylyltransferase	-
EL079_RS05305 (NCTC10713_01107)	rsmD	1091617..1092165 (-)	549	WP_025271932.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25185.47 Da
• Isoelectric Point: 8.3081

>NTDB_id=1120029 EL079_RS05275 WP_018543646.1 1087095..1087769(+) (cclA/cilC) [Streptococcus anginosus strain NCTC10713]
MIHFYFFLVGSIVASFLGLVVDRFPEQSILVPSSHCNACGQKLAPRDLVPVLSQLINRLRCRFCNSKIPIRYILLELTGG
CLFLATSLGYLNINRLVLLAMGMTLSLYDQREQEYPLLIWLIFHIFLLFLTSFNLLMVAFLALGILAHFVDLRIGAGDFL
FLASCSTIFHLTEVLLIIQIASIIGLLLFGLKSKKDRLAFVPCLFCGSSILIMIQFIVLHQNAL

Nucleotide

• Length: 675 bp

>NTDB_id=1120029 EL079_RS05275 WP_018543646.1 1087095..1087769(+) (cclA/cilC) [Streptococcus anginosus strain NCTC10713]
ATGATTCATTTTTATTTTTTCTTGGTTGGAAGCATTGTAGCTTCCTTTTTAGGGCTGGTCGTTGATCGTTTCCCTGAACA
GTCTATTCTCGTTCCTTCCAGTCATTGTAATGCTTGTGGACAGAAATTAGCACCTCGTGATTTAGTCCCTGTCCTTTCTC
AGCTTATCAATCGACTGCGTTGTCGGTTTTGCAACTCAAAAATTCCCATCCGTTACATCCTTCTAGAACTAACTGGTGGC
TGTCTCTTTCTTGCAACATCTTTAGGTTATCTAAACATCAACCGGCTCGTTTTGCTTGCAATGGGAATGACCTTATCCCT
TTATGATCAAAGAGAACAAGAATATCCTCTCCTCATCTGGTTAATCTTTCATATTTTTCTCCTTTTTTTGACAAGCTTCA
ATCTTTTAATGGTTGCTTTTTTAGCACTTGGGATTTTGGCTCACTTCGTTGATTTACGTATCGGTGCAGGAGACTTTCTT
TTTCTGGCATCTTGCTCAACTATTTTTCATCTGACTGAAGTTCTTCTCATTATTCAAATTGCTAGTATCATTGGTCTGCT
CCTTTTTGGTTTAAAATCAAAAAAAGACAGGTTAGCCTTTGTTCCCTGTCTTTTCTGTGGTAGCAGCATCCTGATAATGA
TACAATTTATCGTTCTTCACCAAAATGCCTTATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-87)

3D structure

• AlphaFold DB: A0A448AIB9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus mitis SK321	57.075	94.643	0.54
cclA/cilC	Streptococcus mitis NCTC 12261	56.604	94.643	0.536
cclA/cilC	Streptococcus pneumoniae TIGR4	56.132	94.643	0.531
cclA/cilC	Streptococcus pneumoniae Rx1	55.66	94.643	0.527
cclA/cilC	Streptococcus pneumoniae D39	55.66	94.643	0.527
cclA/cilC	Streptococcus pneumoniae R6	55.66	94.643	0.527