Detailed information NTG1111681

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: HMPREF9319_RS02545
• Genome accession: NZ_GL397128
• Coordinates: 511380..513611 (+)
• Length: 743 a.a.
• NCBI ID: WP_041972902.1
• Uniprot ID: -
• Organism: Streptococcus equinus ATCC 700338
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 506380..518611

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF9319_RS02515 (HMPREF9319_0511)	-	507030..507890 (+)	861	WP_003063816.1	helix-turn-helix transcriptional regulator	-
HMPREF9319_RS02520 (HMPREF9319_0512)	-	507895..508524 (+)	630	WP_052292720.1	ROK family protein	-
HMPREF9319_RS02525 (HMPREF9319_0513)	-	508756..509037 (-)	282	WP_003063819.1	GIY-YIG nuclease family protein	-
HMPREF9319_RS02530 (HMPREF9319_0514)	-	509012..509773 (-)	762	WP_003063822.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
HMPREF9319_RS02535 (HMPREF9319_0515)	-	509881..510627 (+)	747	WP_003063827.1	lysophospholipid acyltransferase family protein	-
HMPREF9319_RS02540 (HMPREF9319_0516)	comEA	510722..511387 (+)	666	WP_003063831.1	helix-hairpin-helix domain-containing protein	Machinery gene
HMPREF9319_RS02545 (HMPREF9319_0517)	comEC/celB	511380..513611 (+)	2232	WP_041972902.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
HMPREF9319_RS02550 (HMPREF9319_0518)	holA	513685..514722 (+)	1038	WP_003063837.1	DNA polymerase III subunit delta	-
HMPREF9319_RS02555 (HMPREF9319_0519)	sodA	514811..515419 (+)	609	WP_041972900.1	superoxide dismutase SodA	-
HMPREF9319_RS02560 (HMPREF9319_0520)	-	515568..516293 (+)	726	WP_003063840.1	YebC/PmpR family DNA-binding transcriptional regulator	-
HMPREF9319_RS02565 (HMPREF9319_0521)	queA	516325..517353 (-)	1029	WP_003063841.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
HMPREF9319_RS02570 (HMPREF9319_0522)	-	517529..518029 (+)	501	WP_003063844.1	VIT1/CCC1 transporter family protein	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 83864.19 Da
• Isoelectric Point: 8.2231

>NTDB_id=1111681 HMPREF9319_RS02545 WP_041972902.1 511380..513611(+) (comEC/celB) [Streptococcus equinus ATCC 700338]
MIKYFPIKPIQLAFLLILLYYFCFSKVIGCLMFLLLALVFLWQQYGWKAWCQVCLCLTCFAVFFLTKANQTEQAYQAAPD
HLTKIQMIPDTISVNGDLLSFRGKEAGRTYQIFYTLKSEKEQHFFKTLSQTVVLSGDMDLEEATPQRNFDGFDYRTYLKH
EGIYRVVNLSAINNVELVHKTTLWDKLHDVRRKAIVSIQQHFPAPMQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFAL
SGMQVGFFVGAFRFFFLRLGLRRDYVDILQIPFSLVYAGLTGFSVSVIRSLIQSAFANLGIKKLDNLALTLFVLFIVMPN
FLLTMGGILSFTYAFILSFINFDDISRYQKIIAESLTISLASLPLLIHFFAVFQPLSVLLTAIFSVAFDTIMLPMLSIIF
ILSPLVKLTCFNGCFVFLETVIKHTKAILGGPIVFGKPNLGILVLLFLMLGVLYDCWRRKKTAIFLVSLVALLFFQIKHP
LENEVTVVDIGQGDSIFVRDVKGNTLLIDVGGKVSFSEKNAWQERLTDSNAERTLIPYLNSRGVGKIDQLVLTHTDTDHM
GDMLEVAKQVKIGEILVSQGSLTKPDFVAKLQAMKTKVRVVTAGDVLPIMGSHLQVLYPSQTGDGGNNDSVVLYGNLLGK
NFLFTGDLEEEGEQELIATYPNLPVDVLKAGHHGSKGSSSSEFLAHISPQIALISAGQNNRYKHPHQETLERFRVQNMTI
YRTDEQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2232 bp

>NTDB_id=1111681 HMPREF9319_RS02545 WP_041972902.1 511380..513611(+) (comEC/celB) [Streptococcus equinus ATCC 700338]
TTGATTAAATATTTTCCCATTAAGCCAATTCAATTGGCTTTTTTGCTCATTTTGCTCTATTATTTTTGCTTTTCAAAAGT
GATTGGGTGTTTGATGTTTCTCTTGCTAGCCTTGGTGTTTTTATGGCAACAGTATGGTTGGAAGGCTTGGTGTCAAGTTT
GCTTGTGTTTAACCTGTTTTGCGGTATTTTTTCTGACTAAGGCTAATCAGACAGAGCAGGCTTATCAAGCAGCACCAGAT
CATTTAACAAAAATCCAGATGATTCCTGACACGATTTCGGTCAATGGGGATTTGCTGTCCTTTCGAGGTAAGGAAGCTGG
GCGGACTTATCAGATTTTTTATACCTTGAAATCGGAGAAAGAACAGCATTTTTTTAAGACATTAAGTCAAACGGTTGTTT
TATCTGGTGATATGGATTTGGAAGAAGCAACGCCCCAGCGGAATTTTGATGGTTTTGATTATCGTACTTACCTTAAACAT
GAAGGTATTTATCGTGTGGTAAATTTGTCGGCGATTAACAATGTTGAACTTGTTCATAAGACGACTTTGTGGGATAAGCT
ACATGATGTTCGACGAAAGGCTATTGTTAGTATTCAGCAGCATTTTCCTGCTCCTATGCAACATTATATGACTGGGCTTT
TGTTTGGCTATCTGGATAAATCGTTTGATGAGATGAGTGATGTTTACACGAGTTTAGGAATTATTCACCTCTTTGCTCTT
TCAGGCATGCAGGTTGGCTTTTTTGTGGGGGCATTCCGCTTTTTCTTTCTACGTCTTGGGTTACGCCGAGATTATGTGGA
CATACTACAAATCCCATTTTCACTCGTCTATGCGGGGCTGACTGGCTTTTCTGTTTCGGTAATTCGGAGTTTAATTCAAT
CTGCTTTTGCAAATCTTGGTATTAAAAAATTAGATAACTTGGCTTTAACTTTGTTTGTTCTTTTTATAGTTATGCCAAAT
TTTCTGCTGACGATGGGAGGCATTCTTTCGTTTACTTACGCTTTTATTCTCAGTTTTATTAACTTTGATGACATTAGTCG
CTATCAGAAAATCATTGCGGAAAGTTTGACGATTTCATTAGCCAGTTTGCCCTTGTTAATTCATTTTTTTGCTGTGTTTC
AACCGTTATCTGTCTTATTGACCGCAATTTTTTCTGTGGCATTTGACACTATTATGTTGCCAATGCTATCAATCATTTTT
ATTTTATCGCCCTTGGTTAAACTGACTTGTTTTAATGGTTGTTTTGTTTTCTTGGAAACTGTTATCAAGCACACTAAGGC
AATTTTGGGCGGTCCGATTGTTTTTGGTAAACCAAATCTTGGTATCTTGGTGCTACTATTTTTAATGTTAGGCGTGCTTT
ATGATTGCTGGCGACGAAAGAAAACGGCAATTTTTCTTGTCAGCTTAGTAGCTCTGCTATTTTTTCAAATCAAGCATCCG
CTAGAAAACGAGGTGACGGTGGTTGATATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAGGGGAATACGCTGCT
AATTGATGTGGGCGGAAAGGTGAGTTTTAGTGAGAAGAACGCGTGGCAGGAGCGGCTGACGGATAGCAATGCGGAGCGAA
CGTTGATTCCTTATCTCAACAGTCGCGGCGTTGGAAAAATTGACCAGTTAGTTCTGACGCACACGGATACTGACCACATG
GGAGATATGCTAGAGGTGGCAAAGCAGGTGAAAATTGGTGAAATTCTGGTTAGTCAGGGAAGTTTGACAAAGCCAGATTT
TGTGGCGAAATTACAAGCCATGAAAACCAAGGTGCGCGTGGTAACAGCTGGTGATGTTTTGCCGATTATGGGAAGTCACC
TGCAAGTGCTTTATCCGAGCCAGACTGGTGATGGTGGTAACAATGACTCGGTGGTGCTTTATGGGAATCTTTTGGGTAAG
AATTTCTTGTTTACAGGAGATTTGGAAGAAGAAGGCGAGCAAGAGTTGATAGCAACTTATCCCAATCTGCCGGTTGATGT
CTTAAAAGCAGGGCATCATGGCTCAAAAGGATCATCAAGTTCAGAATTTCTCGCTCACATTTCACCGCAAATTGCTTTGA
TTTCCGCAGGGCAAAATAACCGATACAAACATCCTCACCAAGAAACGCTTGAACGCTTCCGAGTACAAAACATGACCATT
TACCGCACAGACGAGCAAGGCGCTATCCGCTTTAGAGGACTAAATCACTGGAAAATCGAAACAGTGAGGTAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (213-459)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-697)

• Domain of unknown function (DUF4131) (DUF4131) (27-174)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	52.83	99.865	0.528
comEC/celB	Streptococcus mitis SK321	52.291	99.865	0.522
comEC/celB	Streptococcus pneumoniae TIGR4	51.279	100	0.513
comEC/celB	Streptococcus pneumoniae Rx1	50.74	100	0.507
comEC/celB	Streptococcus pneumoniae D39	50.74	100	0.507
comEC/celB	Streptococcus pneumoniae R6	50.74	100	0.507
comEC	Lactococcus lactis subsp. cremoris KW2	47.645	100	0.476