Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ACMX2G_RS04295 Genome accession   NZ_CP180375
Coordinates   842376..843020 (-) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain NJN-6     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 837376..848020
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACMX2G_RS04260 (ACMX2G_04260) - 838561..838992 (+) 432 WP_003152066.1 Na(+)/H(+) antiporter subunit B -
  ACMX2G_RS04265 (ACMX2G_04265) - 838992..839333 (+) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  ACMX2G_RS04270 (ACMX2G_04270) - 839326..840807 (+) 1482 WP_014305717.1 Na+/H+ antiporter subunit D -
  ACMX2G_RS04275 (ACMX2G_04275) - 840813..841289 (+) 477 WP_003152059.1 Na+/H+ antiporter subunit E -
  ACMX2G_RS04280 (ACMX2G_04280) - 841289..841573 (+) 285 WP_003152057.1 Na(+)/H(+) antiporter subunit F1 -
  ACMX2G_RS04285 (ACMX2G_04285) mnhG 841557..841931 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  ACMX2G_RS04290 (ACMX2G_04290) - 841971..842354 (-) 384 WP_003152054.1 hotdog fold thioesterase -
  ACMX2G_RS04295 (ACMX2G_04295) comA 842376..843020 (-) 645 WP_003152052.1 response regulator transcription factor Regulator
  ACMX2G_RS04300 (ACMX2G_04300) comP 843101..845392 (-) 2292 WP_014305719.1 histidine kinase Regulator
  ACMX2G_RS04305 (ACMX2G_04305) comX 845404..845568 (-) 165 WP_007613432.1 competence pheromone ComX -
  ACMX2G_RS04310 (ACMX2G_04310) - 845568..846479 (-) 912 WP_014305720.1 polyprenyl synthetase family protein -
  ACMX2G_RS04315 (ACMX2G_04315) degQ 846631..846771 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  ACMX2G_RS04320 (ACMX2G_04320) - 847237..847578 (+) 342 WP_014305721.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=1095465 ACMX2G_RS04295 WP_003152052.1 842376..843020(-) (comA) [Bacillus velezensis strain NJN-6]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1095465 ACMX2G_RS04295 WP_003152052.1 842376..843020(-) (comA) [Bacillus velezensis strain NJN-6]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATCGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAATAAGCTGAATGTCGGCTCCCGAACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864

Multiple sequence alignment