Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   ACIO06_RS09610 Genome accession   NZ_CP173230
Coordinates   1915455..1916777 (+) Length   440 a.a.
NCBI ID   WP_410679840.1    Uniprot ID   -
Organism   Avibacterium paragallinarum strain npAP/GA-USA/20231216/S1-2     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1910455..1921777
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIO06_RS09590 (ACIO06_09590) - 1910557..1913106 (-) 2550 WP_410679836.1 penicillin-binding protein 1A -
  ACIO06_RS09595 (ACIO06_09595) - 1913265..1914032 (+) 768 WP_410679837.1 hypothetical protein -
  ACIO06_RS09600 (ACIO06_09600) - 1914062..1915087 (+) 1026 WP_410679838.1 PilN domain-containing protein -
  ACIO06_RS09605 (ACIO06_09605) - 1915087..1915446 (+) 360 WP_410679839.1 hypothetical protein -
  ACIO06_RS09610 (ACIO06_09610) comE 1915455..1916777 (+) 1323 WP_410679840.1 type IV pilus secretin PilQ Machinery gene
  ACIO06_RS09615 (ACIO06_09615) aroK 1916978..1917538 (+) 561 WP_272487554.1 shikimate kinase AroK -
  ACIO06_RS09620 (ACIO06_09620) aroB 1917555..1918643 (+) 1089 WP_410679841.1 3-dehydroquinate synthase -
  ACIO06_RS09625 (ACIO06_09625) - 1918649..1919539 (+) 891 WP_017806825.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  ACIO06_RS09630 (ACIO06_09630) - 1919511..1919816 (-) 306 WP_035688115.1 DciA family protein -
  ACIO06_RS09635 (ACIO06_09635) secM 1919922..1920233 (+) 312 WP_410679842.1 secA translation cis-regulator SecM -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 48593.63 Da        Isoelectric Point: 6.1197

>NTDB_id=1070971 ACIO06_RS09610 WP_410679840.1 1915455..1916777(+) (comE) [Avibacterium paragallinarum strain npAP/GA-USA/20231216/S1-2]
MKLLNIIKNILLFFLILSYPFRLVNASDENNTFSVHLKQAPLVDTVQYLAGYQKINLVIDDELSGSISLQLQNTTLLQLL
KSIAEIKHLRFWENNGIYYLSQSQATNQENVVLNSSTDIATSADMLITSIKLHYAKASEVMKALTSGNGSLLTVNGSISF
DERNNLLIIQDEAKKIKQIRKLVADMDKPIQQIIIEARIATISDESLKELGVRWGIFSPSDISHSVSGSLNANGFSNITD
NLNINFATSSNPAGSVALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVNNGKNDTQSIE
FREAVLGLEVTPHLLKHNGILLDLVVSQNAPGGRVSYGENEVISIDKQEINTQVFAQDGETIVLGGIFHDTITKALDKVP
ILGDIPGIKRLFSKEVERHQKRELVIFVTPRLIRSGTVEE

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=1070971 ACIO06_RS09610 WP_410679840.1 1915455..1916777(+) (comE) [Avibacterium paragallinarum strain npAP/GA-USA/20231216/S1-2]
ATGAAGTTACTAAATATAATAAAGAATATTCTTTTATTTTTTCTTATTCTATCCTATCCATTTAGACTGGTTAATGCAAG
TGACGAAAATAATACATTCTCTGTTCATTTAAAGCAAGCTCCATTAGTAGATACTGTACAATATTTAGCTGGGTATCAAA
AAATCAATTTAGTCATAGATGATGAATTGTCTGGTTCAATATCTTTGCAATTGCAAAATACAACATTACTTCAATTATTA
AAATCTATCGCTGAAATAAAACATTTGCGGTTTTGGGAAAATAATGGGATATATTATTTAAGTCAGTCGCAAGCAACTAA
TCAAGAAAATGTAGTGTTAAATTCATCAACAGACATAGCAACATCAGCAGATATGTTAATAACTTCAATAAAGTTGCACT
ATGCCAAAGCATCCGAGGTAATGAAAGCCCTCACTTCAGGGAATGGCTCTTTATTAACAGTAAATGGAAGTATAAGTTTT
GATGAACGCAATAATTTACTCATTATCCAAGATGAAGCTAAAAAAATAAAACAAATTAGGAAATTGGTAGCGGATATGGA
TAAACCCATTCAGCAAATTATTATTGAAGCTCGTATTGCCACAATTAGCGATGAAAGTTTAAAAGAATTGGGAGTCAGAT
GGGGAATTTTTTCTCCCTCAGATATAAGCCATAGCGTTTCTGGAAGTTTAAATGCAAATGGATTCTCAAATATTACGGAT
AATCTAAATATTAATTTTGCGACGAGTTCAAATCCTGCAGGTTCGGTAGCTTTGCAAGTAGCTAAAATTAATGGAAGGTT
ATTAGATTTAGAGTTGACAGCATTAGAAAGAGAAAATAACGTTGAAATTATTGCGAGTCCACGATTATTGACTACGAATA
AGAAAAGCGCAAGTATCAAGCAAGGTACAGAAATCCCCTATGTAGTGAATAATGGAAAAAATGATACGCAGTCTATTGAA
TTCCGAGAGGCTGTACTTGGGCTTGAAGTTACACCTCATTTATTAAAGCATAACGGTATTTTACTTGATCTTGTTGTTAG
CCAGAATGCACCTGGAGGACGAGTATCTTATGGAGAAAATGAGGTGATTTCTATTGATAAACAGGAAATTAATACGCAAG
TCTTTGCACAAGACGGCGAAACGATTGTATTGGGCGGAATTTTCCACGATACGATTACTAAAGCACTTGATAAAGTACCA
ATTTTAGGAGACATACCTGGAATAAAAAGGCTATTTAGTAAGGAAGTCGAGAGACATCAAAAGAGGGAACTCGTTATTTT
TGTTACACCACGCTTAATTCGTAGTGGTACAGTAGAGGAATGA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(274-434)

Bacterial type II/III secretion system short domain (Secretin_N)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

64.419

97.727

0.63
  comE Haemophilus influenzae 86-028NP

64.554

96.818

0.625
  comE Glaesserella parasuis strain SC1401

49.649

97.045

0.482
  pilQ Vibrio campbellii strain DS40M4

39.765

96.591

0.384
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

40.048

94.773

0.38
  pilQ Vibrio cholerae strain A1552

40.048

94.773

0.38

Multiple sequence alignment