Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACFIOR_RS04375 Genome accession   NZ_CP170409
Coordinates   846913..847542 (+) Length   209 a.a.
NCBI ID   WP_000153535.1    Uniprot ID   W8TS97
Organism   Staphylococcus aureus strain t359     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 841913..852542
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOR_RS04350 - 842293..843279 (-) 987 WP_000999713.1 FUSC family protein -
  ACFIOR_RS04355 map 843810..844592 (+) 783 WP_168768559.1 type I methionyl aminopeptidase -
  ACFIOR_RS04360 - 844781..845167 (+) 387 WP_001110179.1 hypothetical protein -
  ACFIOR_RS04365 liaF 845182..845883 (+) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  ACFIOR_RS04370 vraS 845880..846923 (+) 1044 WP_001017131.1 sensor histidine kinase Regulator
  ACFIOR_RS04375 vraR 846913..847542 (+) 630 WP_000153535.1 two-component system response regulator VraR Regulator
  ACFIOR_RS04380 - 847654..848871 (-) 1218 WP_000037079.1 YihY/virulence factor BrkB family protein -
  ACFIOR_RS04385 - 849149..849424 (-) 276 WP_000428172.1 YtxH domain-containing protein -
  ACFIOR_RS04390 - 849431..849895 (-) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  ACFIOR_RS04395 - 850042..850242 (+) 201 WP_000180463.1 DUF1128 family protein -
  ACFIOR_RS04400 - 850245..851501 (+) 1257 WP_001793428.1 aminopeptidase -
  ACFIOR_RS04405 - 851590..852120 (+) 531 WP_000184383.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23559.32 Da        Isoelectric Point: 5.3935

>NTDB_id=1056881 ACFIOR_RS04375 WP_000153535.1 846913..847542(+) (vraR) [Staphylococcus aureus strain t359]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1056881 ACFIOR_RS04375 WP_000153535.1 846913..847542(+) (vraR) [Staphylococcus aureus strain t359]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAGGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTCATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8TS97

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

100

100

1
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment