Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   ACB356_RS08440 Genome accession   NZ_CP166998
Coordinates   1709024..1709737 (+) Length   237 a.a.
NCBI ID   WP_002991336.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 35     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1704024..1714737
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB356_RS08430 (ACB356_08430) treC 1705094..1706722 (-) 1629 WP_002991331.1 alpha,alpha-phosphotrehalase -
  ACB356_RS08435 (ACB356_08435) treP 1706789..1708813 (-) 2025 WP_002991333.1 PTS system trehalose-specific EIIBC component -
  ACB356_RS08440 (ACB356_08440) treR 1709024..1709737 (+) 714 WP_002991336.1 trehalose operon repressor Regulator
  ACB356_RS08445 (ACB356_08445) - 1710016..1710354 (-) 339 WP_002991339.1 helix-turn-helix domain-containing protein -
  ACB356_RS08450 (ACB356_08450) - 1710540..1711388 (+) 849 Protein_1603 VOC family protein -
  ACB356_RS08455 (ACB356_08455) yaaA 1711430..1712161 (+) 732 WP_002991342.1 peroxide stress protein YaaA -
  ACB356_RS08460 (ACB356_08460) nrdG 1712335..1712949 (-) 615 WP_002991344.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  ACB356_RS08465 (ACB356_08465) - 1712949..1713458 (-) 510 WP_002991345.1 GNAT family N-acetyltransferase -
  ACB356_RS08470 (ACB356_08470) - 1713467..1714402 (-) 936 WP_002991347.1 Gfo/Idh/MocA family protein -
  ACB356_RS08475 (ACB356_08475) - 1714431..1714577 (-) 147 WP_002982210.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27608.78 Da        Isoelectric Point: 9.6226

>NTDB_id=1036725 ACB356_RS08440 WP_002991336.1 1709024..1709737(+) (treR) [Streptococcus pyogenes strain Isolate 35]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFSRRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=1036725 ACB356_RS08440 WP_002991336.1 1709024..1709737(+) (treR) [Streptococcus pyogenes strain Isolate 35]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAAACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACGCGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTTTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTTCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.376

98.734

0.675

Multiple sequence alignment