ICEberg
I. Information of ICE
ICEberg ID627
Name TR2 This is a predicted ICE derived from literature
OrganismStreptomyces scabiei 87.22
Size (bp)154097
GC content [Genome] (%)68.32
Insertion siteTACACATTGAAGCGGAAC;TAGACATTGAAGCGGAAC
Function-
Species that ICE can be transferred to-
Nucleotide SequenceNC_013929 (complete ICE sequence in this genome)
Replicon-
Genome coordinates3617692..3771788 
Putative oriT region -
Putative relaxase -


II. ICE interaction with IME/CIME/

The Interaction Network among ICE/IME/CIME


Detailed Informatioin of the Interaction Network
# ICE  Inter_Ele [Type] Methods Donors Recipients Exper_Ref 
1TR2 TR1 [CIME] experimentalin cis Streptomyces scabiei Streptomyces diastatochromogenes 27977935

experimental This is an interactioin derived from experimental literature



The graph information of TR2 components from NC_013929
Complete gene list of TR2 from NC_013929
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)		 *Reannotation 
1txtE3613916..3615136 [+], 12214-nitrotryptophan synthase
2SCAB_RS151003615200..3616372 [+], 1173nitric oxide synthase oxygenase
3SCAB_RS151103617139..3617423 [-], 285hypothetical protein
4SCAB_RS448453617834..3618586 [-], 753site-specific integraseIntegrase 
5SCAB_RS151203619118..3619351 [-], 234DNA-binding protein
6SCAB_RS151253620559..3620882 [+], 324divalent-cation tolerance protein CutA
7SCAB_RS151303620941..3622182 [-], 1242XRE family transcriptional regulator
8SCAB_RS151353622592..3623452 [-], 861DNA-binding protein
9SCAB_RS151403623531..3624334 [-], 804aminotransferase
10SCAB_RS151453624541..3624975 [+], 435ATP-binding protein
11SCAB_RS151503625463..3626128 [+], 666hypothetical protein
12SCAB_RS151553626442..3626933 [+], 492hypothetical protein
13SCAB_RS151603626930..3628099 [+], 1170hypothetical protein
14SCAB_RS151653628089..3628931 [+], 843hypothetical protein
15fxlM3629681..3630922 [+], 1242methyltransferase, FxLD system
16SCAB_RS448503630960..3631130 [+], 171FxLD family lantipeptide
17SCAB_RS151753631218..3634346 [+], 3129lantibiotic dehydratase
18SCAB_RS151803634343..3635575 [+], 1233lanthionine synthetase
19SCAB_RS151853635598..3636644 [+], 1047hypothetical protein
20SCAB_RS151903636644..3637609 [+], 966hypothetical protein
21SCAB_RS152003638794..3640098 [+], 1305ATP-binding protein
22SCAB_RS437403640095..3640511 [+], 417hypothetical protein
23SCAB_RS152103640508..3640870 [+], 363DUF742 domain-containing protein
24SCAB_RS152153640875..3641468 [+], 594ATP-binding protein
25SCAB_RS152203641465..3642787 [+], 1323cytochrome P450
26SCAB_RS152253642688..3643950 [+], 1263cytochrome P450
27SCAB_RS437453644067..3644522 [+], 456hypothetical protein
28SCAB_RS152403645758..3646717 [+], 960hypothetical protein
29SCAB_RS152453646843..3647820 [+], 978hypothetical protein
30SCAB_RS448553647886..3648104 [+], 219hypothetical protein
31SCAB_RS152553649247..3649720 [-], 474hypothetical protein
32SCAB_RS152603649830..3651026 [-], 1197hypothetical protein
33SCAB_RS152653651023..3651577 [-], 555hypothetical protein
34SCAB_RS152703651752..3652189 [-], 438XRE family transcriptional regulator
35SCAB_RS152753652930..3653820 [+], 891helix-turn-helix domain-containing protein
36SCAB_RS152803653823..3654521 [+], 699hypothetical protein
37SCAB_RS152853654684..3655325 [+], 642WhiB family transcriptional regulator
38SCAB_RS152903655322..3657031 [+], 1710hypothetical protein
39SCAB_RS152953657028..3657219 [+], 192hypothetical protein
40SCAB_RS153003657306..3657542 [+], 237hypothetical protein
41SCAB_RS153053657869..3658156 [+], 288plasmid mobilization relaxosome protein MobC
42SCAB_RS153103658153..3659892 [+], 1740mobilization protein
43SCAB_RS153153660321..3660764 [+], 444hypothetical protein
44SCAB_RS153203660845..3661540 [+], 696hypothetical protein
45SCAB_RS153253662163..3662984 [-], 822DUF317 domain-containing protein
46SCAB_RS153303663000..3663290 [-], 291hypothetical protein
47SCAB_RS153353663371..3663745 [-], 375DUF317 domain-containing protein
48SCAB_RS153403663963..3664715 [+], 753TnsA-like heteromeric transposase endonuclease subunit
49SCAB_RS153453664712..3666610 [+], 1899integrase
50SCAB_RS153503666643..3667659 [+], 1017ATP/GTP-binding protein
51SCAB_RS153553668714..3669001 [+], 288hypothetical protein
52SCAB_RS153603669292..3671658 [+], 2367tetratricopeptide repeat protein
53SCAB_RS153653672169..3675261 [+], 3093CHAT domain-containing protein
54SCAB_RS153703675261..3676001 [+], 741hypothetical protein
55SCAB_RS153753676445..3677203 [+], 759hypothetical protein
56SCAB_RS153803677345..3678658 [+], 1314hypothetical protein
57SCAB_RS153853679261..3679635 [+], 375hypothetical protein
58SCAB_RS153903679704..3681866 [+], 2163NACHT domain-containing protein
59SCAB_RS448603682183..3683763 [-], 1581serine/threonine protein kinase
60SCAB_RS153953683971..3684174 [+], 204hypothetical protein
61SCAB_RS154003684212..3684631 [+], 420hypothetical protein
62SCAB_RS154053684798..3685820 [-], 1023ATP-dependent DNA ligase
63SCAB_RS154103685955..3686179 [+], 225hypothetical protein
64SCAB_RS154153686350..3687360 [-], 1011ligand-binding membrane protein
65SCAB_RS154253688237..3688725 [-], 489hypothetical protein
66SCAB_RS154303688755..3689615 [-], 861DUF317 domain-containing protein
67SCAB_RS154353689663..3690316 [-], 654HAD family phosphatase
68SCAB_RS154403690313..3691476 [-], 1164MFS transporter
69SCAB_RS154453691473..3692726 [-], 1254ATP-grasp domain-containing protein
70SCAB_RS154503692781..3693083 [-], 303hypothetical protein
71SCAB_RS154553693119..3694354 [-], 1236MFS transporter
72SCAB_RS154603694351..3694869 [-], 519hypothetical protein
73SCAB_RS154653694866..3695708 [-], 843MarR family transcriptional regulator
74SCAB_RS154703695749..3696060 [-], 312hypothetical protein
75SCAB_RS154753696173..3696616 [-], 444hypothetical protein
76SCAB_RS154803696613..3697095 [-], 483hypothetical protein
77SCAB_RS154853697196..3697513 [-], 318SH3 domain-containing protein
78SCAB_RS154903697695..3698444 [-], 750hypothetical protein
79SCAB_RS154953698462..3699160 [-], 699hypothetical protein
80SCAB_RS155003699179..3699664 [-], 486hypothetical protein
81SCAB_RS155053699661..3700314 [-], 654DUF4913 domain-containing protein
82SCAB_RS155103700454..3701209 [-], 756site-specific DNA-methyltransferase
83SCAB_RS155153701724..3702854 [+], 1131NlpC/P60 family proteinTcpG, T4SS component 
84SCAB_RS155203702994..3703308 [+], 315hypothetical protein
85SCAB_RS155253703308..3704000 [+], 693hypothetical protein
86SCAB_RS155303704037..3705413 [+], 1377ATP-binding protein
87SCAB_RS155353705525..3706967 [+], 1443hypothetical protein
88SCAB_RS155403707162..3707635 [+], 474hypothetical protein
89SCAB_RS155453707659..3708198 [+], 540hypothetical protein
90SCAB_RS155503708245..3709759 [+], 1515ATP-binding protein
91SCAB_RS448653710181..3710399 [-], 219hypothetical protein
92SCAB_RS155603710428..3711345 [+], 918hypothetical protein
93SCAB_RS155653711583..3712338 [+], 756hypothetical protein
94SCAB_RS437503712451..3713569 [+], 1119hypothetical protein
95SCAB_RS155753713743..3714273 [+], 531hypothetical protein
96SCAB_RS155803714264..3714956 [+], 693hypothetical protein
97SCAB_RS155853714953..3715501 [+], 549hypothetical protein
98SCAB_RS155903715538..3716140 [+], 603hypothetical protein
99SCAB_RS155953716190..3716792 [+], 603glycosyltransferase
100SCAB_RS156003716979..3718010 [-], 1032HNH endonuclease
101SCAB_RS156053718010..3719608 [-], 1599lambdoid prophage protein
102SCAB_RS156103719825..3721192 [-], 1368hypothetical protein
103SCAB_RS156153721622..3722125 [+], 504hypothetical protein
104SCAB_RS448703722418..3722870 [+], 453hypothetical protein
105SCAB_RS156203722867..3724066 [+], 1200hypothetical protein
106SCAB_RS448753724110..3724325 [+], 216hypothetical protein
107SCAB_RS156303724459..3725664 [+], 1206AAA family ATPase
108SCAB_RS156353725661..3727460 [+], 1800hypothetical protein
109SCAB_RS156403727678..3728151 [+], 474hypothetical protein
110SCAB_RS156453728252..3728677 [+], 426hypothetical protein
111SCAB_RS156503728674..3729519 [+], 846hypothetical protein
112SCAB_RS156603730251..3731009 [+], 759hypothetical protein
113SCAB_RS156653731006..3731653 [+], 648hypothetical protein
114SCAB_RS156703731670..3732077 [+], 408hypothetical protein
115SCAB_RS156753732351..3732734 [+], 384hypothetical protein
116SCAB_RS156803732731..3733534 [+], 804DUF317 domain-containing protein
117SCAB_RS156853733561..3733917 [+], 357hypothetical protein
118SCAB_RS156953734755..3735321 [+], 567hypothetical protein
119SCAB_RS157053736306..3738102 [+], 1797membrane proteinT4CP 
120SCAB_RS437553739199..3740125 [+], 927alpha/beta fold hydrolase
121SCAB_RS157203740428..3741057 [+], 630hypothetical protein
122SCAB_RS157253741054..3742328 [+], 1275DNA cytosine methyltransferase
123SCAB_RS157303742328..3743446 [+], 1119hypothetical protein
124SCAB_RS157353743512..3743787 [+], 276hypothetical protein
125SCAB_RS157403744025..3744330 [+], 306transposase
126SCAB_RS157453744327..3745220 [+], 894IS3 family transposase
127SCAB_RS448953745377..3748841 [+], 3465CHAT domain-containing protein
128SCAB_RS157503749514..3750749 [-], 1236IS110 family transposase
129SCAB_RS157603752446..3754908 [-], 2463DUF262 domain-containing protein
130SCAB_RS157653754939..3755127 [-], 189hypothetical protein
131SCAB_RS157703755527..3756360 [-], 834phosphoadenosine phosphosulfate reductase
132SCAB_RS157753756357..3759935 [-], 3579ATP-binding protein
133SCAB_RS157803759932..3761038 [-], 1107DUF4007 family protein
134SCAB_RS157853761097..3762272 [-], 1176cysteine desulfurase
135SCAB_RS157903762780..3764354 [+], 1575restriction endonuclease
136SCAB_RS157953764339..3766219 [+], 1881ATP-binding protein
137SCAB_RS158003766222..3767121 [+], 900hypothetical protein
138SCAB_RS158053767293..3767937 [+], 645hypothetical protein
139SCAB_RS158103768149..3768949 [+], 801phosphoadenosine phosphosulfate reductase
140SCAB_RS158153769062..3769913 [-], 852hypothetical protein
141SCAB_RS158203769973..3771415 [-], 1443DNA phosphorothioation-associated putative methyltransferase
142SCAB_RS158253771788..3772654 [-], 867hypothetical protein
143SCAB_RS158303773470..3774360 [-], 891transporter
144SCAB_RS158353774664..3775752 [-], 1089redox-regulated ATPase YchF
145SCAB_RS158403776183..3776788 [+], 606hypothetical protein
 
flank Flanking regions

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins138Fasta
(1) Zhang Y; Loria R (2017). Emergence of Novel Pathogenic Streptomyces Species by Site-Specific Accretion and cis-Mobilization of Pathogenicity Islands. Mol Plant Microbe Interact. 30(1):72-82. [PubMed:27977935] experimental in_silico
(2) Chapleau M; Guertin JF; Farrokhi A; Lerat S; Burrus V; Beaulieu C (2016). Identification of genetic and environmental factors stimulating excision from Streptomyces scabiei chromosome of the toxicogenic region responsible for pathogenicity. Mol Plant Pathol. 17(4):501-9. [PubMed:26177341] experimental in_silico
 
experimental experimental literature
in_silico in silico analysis literature

Genomics & Bioinformatics Group in MML, SJTU