99999

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 5194204..5195939 Replicon chromosome
Accession NZ_CP027723
Organism Pseudomonas orientalis strain 8B

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag C4J98_RS23550 Protein ID WP_124434168.1
Coordinates 5194204..5194848 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag C4J98_RS23555 Protein ID WP_124434169.1
Coordinates 5194845..5195939 (+) Length 365 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J98_RS23520 5189796..5190323 + 528 WP_005791810.1 inorganic diphosphatase -
C4J98_RS23525 5190535..5191305 + 771 WP_124434165.1 helix-turn-helix transcriptional regulator -
C4J98_RS23535 5191548..5192651 - 1104 WP_124434714.1 DUF91 domain-containing protein -
C4J98_RS23545 5193635..5194207 + 573 WP_124434167.1 DUF4433 domain-containing protein -
C4J98_RS23550 5194204..5194848 + 645 WP_124434168.1 DUF4433 domain-containing protein Toxin
C4J98_RS23555 5194845..5195939 + 1095 WP_124434169.1 macro domain-containing protein Antitoxin
C4J98_RS23560 5195993..5196388 - 396 WP_124434170.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
C4J98_RS23565 5196378..5197142 - 765 WP_124434171.1 type IV toxin-antitoxin system AbiEi family antitoxin -
C4J98_RS23570 5197350..5197982 + 633 WP_057703186.1 hydrolase -
C4J98_RS23575 5198268..5198510 + 243 WP_003176346.1 exodeoxyribonuclease VII small subunit -
C4J98_RS23580 5198507..5199394 + 888 WP_124427681.1 polyprenyl synthetase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24919.47 Da        Isoelectric Point: 6.6552

>T99999 WP_124434168.1 NZ_CP027723:5194204-5194848 [Pseudomonas orientalis]
MIYNNLNPEKALIWRIVHRDNLPWILDNGLHCASSEVQAAQYVDIGNVDLIDKRRTRCVPIAPSGFLSDYVPFYFTPFSV
MMKNIHSGWSVQRRNNDEIVILVSSLHRVAELGLPFVFTNAHAYPDWTDYYSDLANLHEIDWSILQRRDFKRDPDDPRKM
ERYQAEALIHHHLPITGLLGIMCYTDAMKERIEQDVATRGLTLPVHARPGWYFP

Download         Length: 645 bp

>T99999 NZ_CP027723:5194204-5194848 [Pseudomonas orientalis]
ATGATTTATAACAACCTGAATCCTGAAAAAGCTCTGATCTGGCGAATCGTGCATCGCGACAATCTGCCCTGGATTCTGGA
CAACGGCCTGCACTGCGCCAGCTCAGAGGTGCAGGCTGCTCAATATGTGGACATAGGCAATGTTGATTTAATCGACAAAC
GCCGCACGCGCTGTGTCCCTATTGCTCCTTCAGGCTTTTTGTCAGACTACGTTCCCTTCTATTTCACACCCTTCTCTGTG
ATGATGAAAAATATTCACTCTGGCTGGAGCGTTCAACGACGCAACAATGACGAGATCGTGATTCTGGTCTCCAGCCTCCA
CCGCGTCGCCGAGCTTGGCCTACCGTTCGTCTTCACAAACGCACATGCGTACCCGGATTGGACAGACTATTACAGCGACC
TGGCGAATCTCCACGAGATCGATTGGTCTATCCTTCAACGGCGTGACTTCAAACGTGACCCCGATGACCCTCGCAAAATG
GAGCGTTATCAGGCTGAAGCGCTGATTCACCACCACTTACCGATTACAGGACTCCTTGGCATCATGTGTTACACGGATGC
GATGAAAGAACGCATAGAGCAGGACGTCGCCACAAGAGGCCTGACGTTGCCTGTACATGCTCGTCCGGGATGGTATTTCC
CATGA

Antitoxin


Download         Length: 365 a.a.        Molecular weight: 41224.23 Da        Isoelectric Point: 6.5054

>AT99999 WP_124434169.1 NZ_CP027723:5194845-5195939 [Pseudomonas orientalis]
MIRFTQGNLLEANTEVLVNTVNTVGVMGKGIALMFKERFAENYRVYAAACKAGEVETGKVHVTAVNELDGPRWIVNFPTK
RHWRSPSQMAWITEGLHDLRRFLIENHVKSVAVPPLGAGNGGLKWPDVREQIEDVLSDLDVDVLVFEPSNQYLNVAKRSG
VEQLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKRPGLKNPLDLKFVAHKYGPYANRLEHLLNNLDGSYLH
CDKRISDAENSDVIWFDQDRRAFLQTYLRTEAKEYSQALELTAELIDGFESPFGMELLATVDWLLTQEDVAPTVPALREA
LKRWNGGVAAAARKNKLFDDQALDIALKRLTSSSFSRQMTSCHI

Download         Length: 1095 bp

>AT99999 NZ_CP027723:5194845-5195939 [Pseudomonas orientalis]
ATGATCAGGTTCACCCAGGGCAACCTTCTGGAAGCCAACACCGAAGTCCTCGTCAACACGGTGAATACCGTGGGCGTGAT
GGGAAAGGGCATTGCGCTGATGTTCAAAGAGCGTTTTGCAGAAAACTATCGCGTGTACGCTGCTGCCTGTAAAGCTGGCG
AAGTAGAGACCGGAAAAGTGCACGTAACTGCGGTCAACGAACTGGACGGTCCTCGCTGGATCGTTAACTTCCCGACCAAA
CGTCACTGGCGATCACCATCGCAGATGGCATGGATAACCGAAGGCCTGCACGACCTCCGTCGTTTTCTGATTGAAAACCA
TGTGAAGTCAGTGGCGGTTCCTCCGTTAGGGGCCGGTAACGGTGGTCTAAAATGGCCGGACGTTCGCGAACAGATCGAGG
ATGTCTTGAGCGATCTGGATGTCGATGTGTTGGTTTTTGAGCCATCCAATCAGTATCTGAATGTCGCCAAACGCAGCGGC
GTAGAACAGCTTACGCCTGCGCGCGCGCTCATTGCGGAACTGGTTCGACGCTACTGGGTGTTAGGTATGGAATGCAGCCT
GCTGGAGATTCAGAAACTGGCTTGGTTCCTGGAGCGCGCAATTGAGAAGCGGCCAGGCCTCAAAAACCCACTGGACCTTA
AGTTTGTTGCTCATAAGTACGGGCCGTATGCCAACCGGTTGGAACACCTGCTTAACAATCTGGACGGTAGTTATCTGCAT
TGCGATAAGCGCATCAGCGATGCGGAAAACAGTGATGTGATCTGGTTTGACCAAGACCGCAGAGCCTTTTTACAAACCTA
TCTCAGAACAGAGGCCAAGGAATATTCTCAGGCCCTGGAGCTTACCGCAGAGTTGATCGATGGCTTTGAGTCACCCTTCG
GCATGGAGCTATTGGCAACAGTCGACTGGCTGCTGACCCAGGAAGATGTAGCCCCAACGGTTCCGGCTTTACGTGAGGCA
CTGAAACGATGGAATGGCGGTGTCGCTGCAGCCGCTCGCAAAAACAAGCTGTTTGACGATCAAGCACTTGATATTGCGCT
TAAACGGCTCACCTCCAGCAGCTTCAGCCGTCAAATGACTTCCTGTCATATATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References