Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RHH(antitoxin)
Location 2315327..2315880 Replicon chromosome
Accession NZ_CP027723
Organism Pseudomonas orientalis strain 8B

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag C4J98_RS10585 Protein ID WP_124432382.1
Coordinates 2315587..2315880 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C4J98_RS10580 Protein ID WP_124432381.1
Coordinates 2315327..2315599 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J98_RS10555 2311073..2311579 + 507 WP_124432376.1 GNAT family N-acetyltransferase -
C4J98_RS10560 2311584..2312525 - 942 WP_124432377.1 GlxA family transcriptional regulator -
C4J98_RS10565 2312698..2313327 + 630 WP_124432378.1 TetR/AcrR family transcriptional regulator -
C4J98_RS10570 2313324..2314001 + 678 WP_124432379.1 type 1 glutamine amidotransferase domain-containing protein -
C4J98_RS10575 2314096..2315220 + 1125 WP_124432380.1 alkene reductase -
C4J98_RS10580 2315327..2315599 + 273 WP_124432381.1 CopG family ribbon-helix-helix protein Antitoxin
C4J98_RS10585 2315587..2315880 + 294 WP_124432382.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4J98_RS10590 2315885..2316883 - 999 WP_124432383.1 NAD(P)H-quinone oxidoreductase -
C4J98_RS10595 2317079..2317465 + 387 WP_124432384.1 DoxX family protein -
C4J98_RS10600 2317637..2318455 - 819 WP_124432385.1 alpha/beta hydrolase -
C4J98_RS10605 2318552..2319943 - 1392 WP_124432386.1 alginate export family protein -
C4J98_RS10610 2319940..2320836 - 897 WP_124432387.1 glyoxalase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10920.53 Da        Isoelectric Point: 6.9793

>T99995 WP_124432382.1 NZ_CP027723:2315587-2315880 [Pseudomonas orientalis]
VPRLMMTATALTGLERCRHFLAEKDPQVARRAAQTISRQLLRLESDPDVGRPYDESPELRELVIAFGDAGYVALYRFIPS
ESAVVVLAFRPQREAGY

Download         Length: 294 bp

>T99995 NZ_CP027723:2315587-2315880 [Pseudomonas orientalis]
GTGCCACGACTGATGATGACCGCAACTGCGCTGACCGGGTTGGAACGCTGTCGGCACTTCCTGGCAGAAAAAGACCCGCA
GGTCGCACGTCGGGCCGCCCAGACGATTAGCAGGCAGCTGCTGCGTCTGGAGTCCGACCCTGATGTCGGGCGACCGTACG
ACGAGTCGCCCGAATTGCGAGAACTTGTGATCGCCTTTGGTGACGCCGGTTATGTTGCGTTGTACCGCTTCATCCCTTCG
GAATCAGCGGTTGTGGTCCTGGCCTTTCGTCCTCAACGAGAAGCGGGCTACTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10470.63 Da        Isoelectric Point: 6.0804

>AT99995 WP_124432381.1 NZ_CP027723:2315327-2315599 [Pseudomonas orientalis]
MATSIKIDDELKQRIQLLAGARQRSAHWIMREALSQYVEREEARESFKQEALSSWKHYQETGLHVTGSETRAWLDTWGTE
QASEPPKCHD

Download         Length: 273 bp

>AT99995 NZ_CP027723:2315327-2315599 [Pseudomonas orientalis]
ATGGCCACGTCTATAAAAATCGACGATGAATTGAAGCAGCGTATCCAGCTGTTGGCCGGTGCGCGGCAGCGTAGCGCTCA
CTGGATCATGCGTGAAGCGCTCTCGCAGTATGTCGAGCGGGAAGAAGCCCGTGAGAGCTTCAAGCAGGAAGCGTTGTCGT
CCTGGAAACACTATCAGGAAACGGGGTTGCACGTGACCGGTTCCGAGACTCGAGCCTGGCTTGATACCTGGGGCACGGAG
CAAGCGTCGGAGCCGCCCAAGTGCCACGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References