Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 2413224..2413843 Replicon chromosome
Accession NZ_CP027721
Organism Pseudomonas chlororaphis subsp. aureofaciens strain ChPhzTR36

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag C4K12_RS10960 Protein ID WP_124301294.1
Coordinates 2413661..2413843 (-) Length 61 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag C4K12_RS10955 Protein ID WP_092418556.1
Coordinates 2413224..2413625 (-) Length 134 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K12_RS10940 2409099..2410988 + 1890 WP_124301292.1 PAS domain S-box protein -
C4K12_RS10945 2410985..2411620 + 636 WP_124301293.1 response regulator transcription factor -
C4K12_RS10950 2411714..2412478 + 765 WP_051423542.1 hypothetical protein -
C4K12_RS10955 2413224..2413625 - 402 WP_092418556.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
C4K12_RS10960 2413661..2413843 - 183 WP_124301294.1 type II toxin-antitoxin system HicA family toxin Toxin
C4K12_RS10965 2414208..2414489 - 282 WP_053268620.1 hypothetical protein -
C4K12_RS10970 2415415..2415702 + 288 WP_124314865.1 hypothetical protein -
C4K12_RS10975 2415747..2416877 + 1131 WP_124301296.1 hypothetical protein -
C4K12_RS10980 2417095..2418417 - 1323 WP_124301297.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2407294..2428495 21201


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 61 a.a.        Molecular weight: 6827.99 Da        Isoelectric Point: 11.1724

>T99984 WP_124301294.1 NZ_CP027721:c2413843-2413661 [Pseudomonas chlororaphis subsp. aureofaciens]
VQSRQLIKELEAAGWVLERVTGSHHLFKHPYRPETVPVPHPRKDLPRGTVRAIQKLAGLI

Download         Length: 183 bp

>T99984 NZ_CP027721:c2413843-2413661 [Pseudomonas chlororaphis subsp. aureofaciens]
GTGCAAAGCAGACAGTTGATCAAGGAGCTTGAAGCCGCAGGCTGGGTGCTGGAGCGCGTTACCGGCAGCCATCATCTGTT
CAAGCATCCCTACCGGCCCGAGACCGTTCCGGTGCCTCACCCGAGGAAGGATCTGCCACGGGGGACGGTCAGGGCCATCC
AGAAACTGGCCGGGCTGATATAG

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14588.55 Da        Isoelectric Point: 4.7465

>AT99984 WP_092418556.1 NZ_CP027721:c2413625-2413224 [Pseudomonas chlororaphis subsp. aureofaciens]
VHYPICIEWGDEHTATGIQIPDIPGAVTAGDTFEAAYSAAIEIAHVMLEELAREGQAIPLPSPTGTHRANPDFEGMGWGM
LDIDITPYLGKTEKVNVTLPGYVIQRIDRFVREHNIKSRSSFLADAAMEKLGR

Download         Length: 402 bp

>AT99984 NZ_CP027721:c2413625-2413224 [Pseudomonas chlororaphis subsp. aureofaciens]
GTGCACTATCCCATCTGCATCGAGTGGGGCGACGAGCACACTGCTACCGGCATCCAGATTCCTGACATTCCTGGCGCGGT
CACCGCCGGCGACACCTTCGAGGCCGCGTACAGCGCCGCCATCGAGATCGCCCACGTCATGCTCGAAGAACTGGCCCGTG
AGGGACAAGCCATTCCCCTGCCCTCGCCCACCGGCACACACCGCGCCAACCCCGACTTCGAGGGGATGGGCTGGGGCATG
CTGGATATCGACATCACGCCTTACCTGGGCAAAACCGAAAAGGTCAATGTGACCCTGCCGGGCTACGTGATTCAACGAAT
CGACCGCTTTGTGCGGGAGCACAACATCAAGAGCCGGTCGTCTTTTCTGGCAGATGCGGCGATGGAAAAGCTGGGGCGTT
AA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References