Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/HicA-HicB |
Location | 2413224..2413843 | Replicon | chromosome |
Accession | NZ_CP027721 | ||
Organism | Pseudomonas chlororaphis subsp. aureofaciens strain ChPhzTR36 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | - |
Locus tag | C4K12_RS10960 | Protein ID | WP_124301294.1 |
Coordinates | 2413661..2413843 (-) | Length | 61 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | - |
Locus tag | C4K12_RS10955 | Protein ID | WP_092418556.1 |
Coordinates | 2413224..2413625 (-) | Length | 134 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C4K12_RS10940 | 2409099..2410988 | + | 1890 | WP_124301292.1 | PAS domain S-box protein | - |
C4K12_RS10945 | 2410985..2411620 | + | 636 | WP_124301293.1 | response regulator transcription factor | - |
C4K12_RS10950 | 2411714..2412478 | + | 765 | WP_051423542.1 | hypothetical protein | - |
C4K12_RS10955 | 2413224..2413625 | - | 402 | WP_092418556.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
C4K12_RS10960 | 2413661..2413843 | - | 183 | WP_124301294.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
C4K12_RS10965 | 2414208..2414489 | - | 282 | WP_053268620.1 | hypothetical protein | - |
C4K12_RS10970 | 2415415..2415702 | + | 288 | WP_124314865.1 | hypothetical protein | - |
C4K12_RS10975 | 2415747..2416877 | + | 1131 | WP_124301296.1 | hypothetical protein | - |
C4K12_RS10980 | 2417095..2418417 | - | 1323 | WP_124301297.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 2407294..2428495 | 21201 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 61 a.a. Molecular weight: 6827.99 Da Isoelectric Point: 11.1724
>T99984 WP_124301294.1 NZ_CP027721:c2413843-2413661 [Pseudomonas chlororaphis subsp. aureofaciens]
VQSRQLIKELEAAGWVLERVTGSHHLFKHPYRPETVPVPHPRKDLPRGTVRAIQKLAGLI
VQSRQLIKELEAAGWVLERVTGSHHLFKHPYRPETVPVPHPRKDLPRGTVRAIQKLAGLI
Download Length: 183 bp
>T99984 NZ_CP027721:c2413843-2413661 [Pseudomonas chlororaphis subsp. aureofaciens]
GTGCAAAGCAGACAGTTGATCAAGGAGCTTGAAGCCGCAGGCTGGGTGCTGGAGCGCGTTACCGGCAGCCATCATCTGTT
CAAGCATCCCTACCGGCCCGAGACCGTTCCGGTGCCTCACCCGAGGAAGGATCTGCCACGGGGGACGGTCAGGGCCATCC
AGAAACTGGCCGGGCTGATATAG
GTGCAAAGCAGACAGTTGATCAAGGAGCTTGAAGCCGCAGGCTGGGTGCTGGAGCGCGTTACCGGCAGCCATCATCTGTT
CAAGCATCCCTACCGGCCCGAGACCGTTCCGGTGCCTCACCCGAGGAAGGATCTGCCACGGGGGACGGTCAGGGCCATCC
AGAAACTGGCCGGGCTGATATAG
Antitoxin
Download Length: 134 a.a. Molecular weight: 14588.55 Da Isoelectric Point: 4.7465
>AT99984 WP_092418556.1 NZ_CP027721:c2413625-2413224 [Pseudomonas chlororaphis subsp. aureofaciens]
VHYPICIEWGDEHTATGIQIPDIPGAVTAGDTFEAAYSAAIEIAHVMLEELAREGQAIPLPSPTGTHRANPDFEGMGWGM
LDIDITPYLGKTEKVNVTLPGYVIQRIDRFVREHNIKSRSSFLADAAMEKLGR
VHYPICIEWGDEHTATGIQIPDIPGAVTAGDTFEAAYSAAIEIAHVMLEELAREGQAIPLPSPTGTHRANPDFEGMGWGM
LDIDITPYLGKTEKVNVTLPGYVIQRIDRFVREHNIKSRSSFLADAAMEKLGR
Download Length: 402 bp
>AT99984 NZ_CP027721:c2413625-2413224 [Pseudomonas chlororaphis subsp. aureofaciens]
GTGCACTATCCCATCTGCATCGAGTGGGGCGACGAGCACACTGCTACCGGCATCCAGATTCCTGACATTCCTGGCGCGGT
CACCGCCGGCGACACCTTCGAGGCCGCGTACAGCGCCGCCATCGAGATCGCCCACGTCATGCTCGAAGAACTGGCCCGTG
AGGGACAAGCCATTCCCCTGCCCTCGCCCACCGGCACACACCGCGCCAACCCCGACTTCGAGGGGATGGGCTGGGGCATG
CTGGATATCGACATCACGCCTTACCTGGGCAAAACCGAAAAGGTCAATGTGACCCTGCCGGGCTACGTGATTCAACGAAT
CGACCGCTTTGTGCGGGAGCACAACATCAAGAGCCGGTCGTCTTTTCTGGCAGATGCGGCGATGGAAAAGCTGGGGCGTT
AA
GTGCACTATCCCATCTGCATCGAGTGGGGCGACGAGCACACTGCTACCGGCATCCAGATTCCTGACATTCCTGGCGCGGT
CACCGCCGGCGACACCTTCGAGGCCGCGTACAGCGCCGCCATCGAGATCGCCCACGTCATGCTCGAAGAACTGGCCCGTG
AGGGACAAGCCATTCCCCTGCCCTCGCCCACCGGCACACACCGCGCCAACCCCGACTTCGAGGGGATGGGCTGGGGCATG
CTGGATATCGACATCACGCCTTACCTGGGCAAAACCGAAAAGGTCAATGTGACCCTGCCGGGCTACGTGATTCAACGAAT
CGACCGCTTTGTGCGGGAGCACAACATCAAGAGCCGGTCGTCTTTTCTGGCAGATGCGGCGATGGAAAAGCTGGGGCGTT
AA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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