Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumAB/COG3657-dnstrm_HI1420 |
Location | 6250044..6250633 | Replicon | chromosome |
Accession | NZ_CP027720 | ||
Organism | Pseudomonas chlororaphis subsp. aureofaciens strain DSM 6698 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | A0A554PHZ9 |
Locus tag | C4K13_RS28420 | Protein ID | WP_041987451.1 |
Coordinates | 6250334..6250633 (-) | Length | 100 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | - |
Locus tag | C4K13_RS28415 | Protein ID | WP_041987449.1 |
Coordinates | 6250044..6250337 (-) | Length | 98 a.a. |
Genomic Context
Location: 6248260..6249147 (888 bp)
Type: Others
Protein ID: WP_009051074.1
Type: Others
Protein ID: WP_009051074.1
Location: 6249519..6249911 (393 bp)
Type: Others
Protein ID: WP_009051075.1
Type: Others
Protein ID: WP_009051075.1
Location: 6250804..6251253 (450 bp)
Type: Others
Protein ID: WP_041987453.1
Type: Others
Protein ID: WP_041987453.1
Location: 6254026..6254268 (243 bp)
Type: Others
Protein ID: WP_007924102.1
Type: Others
Protein ID: WP_007924102.1
Location: 6254265..6255152 (888 bp)
Type: Others
Protein ID: WP_009051083.1
Type: Others
Protein ID: WP_009051083.1
Location: 6245585..6246748 (1164 bp)
Type: Others
Protein ID: WP_041987444.1
Type: Others
Protein ID: WP_041987444.1
Location: 6246943..6248133 (1191 bp)
Type: Others
Protein ID: WP_041987447.1
Type: Others
Protein ID: WP_041987447.1
Location: 6250044..6250337 (294 bp)
Type: Antitoxin
Protein ID: WP_041987449.1
Type: Antitoxin
Protein ID: WP_041987449.1
Location: 6250334..6250633 (300 bp)
Type: Toxin
Protein ID: WP_041987451.1
Type: Toxin
Protein ID: WP_041987451.1
Location: 6251278..6252288 (1011 bp)
Type: Others
Protein ID: WP_172833408.1
Type: Others
Protein ID: WP_172833408.1
Location: 6252346..6252645 (300 bp)
Type: Others
Protein ID: WP_009051080.1
Type: Others
Protein ID: WP_009051080.1
Location: 6252709..6253800 (1092 bp)
Type: Others
Protein ID: WP_041987461.1
Type: Others
Protein ID: WP_041987461.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C4K13_RS28395 | 6245585..6246748 | - | 1164 | WP_041987444.1 | acyltransferase | - |
C4K13_RS28400 | 6246943..6248133 | - | 1191 | WP_041987447.1 | serine hydrolase | - |
C4K13_RS28405 | 6248260..6249147 | + | 888 | WP_009051074.1 | LysR family transcriptional regulator | - |
C4K13_RS28410 | 6249519..6249911 | + | 393 | WP_009051075.1 | hypothetical protein | - |
C4K13_RS28415 | 6250044..6250337 | - | 294 | WP_041987449.1 | putative addiction module antidote protein | Antitoxin |
C4K13_RS28420 | 6250334..6250633 | - | 300 | WP_041987451.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
C4K13_RS28425 | 6250804..6251253 | + | 450 | WP_041987453.1 | DUF3828 domain-containing protein | - |
C4K13_RS28430 | 6251278..6252288 | - | 1011 | WP_172833408.1 | NAD(P)-dependent alcohol dehydrogenase | - |
C4K13_RS28435 | 6252346..6252645 | - | 300 | WP_009051080.1 | ArsR family transcriptional regulator | - |
C4K13_RS28440 | 6252709..6253800 | - | 1092 | WP_041987461.1 | nitrite reductase, copper-containing | - |
C4K13_RS28445 | 6254026..6254268 | + | 243 | WP_007924102.1 | exodeoxyribonuclease VII small subunit | - |
C4K13_RS28450 | 6254265..6255152 | + | 888 | WP_009051083.1 | (2E,6E)-farnesyl diphosphate synthase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 100 a.a. Molecular weight: 11231.97 Da Isoelectric Point: 10.6086
>T99979 WP_041987451.1 NZ_CP027720:c6250633-6250334 [Pseudomonas chlororaphis subsp. aureofaciens]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVPPVGEGVSELRIHYGPGYRVYFQQLGSQLVILLCGGDKS
RQSRDIELAKQLARRWSRS
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVPPVGEGVSELRIHYGPGYRVYFQQLGSQLVILLCGGDKS
RQSRDIELAKQLARRWSRS
Download Length: 300 bp
>T99979 NZ_CP027720:c6250633-6250334 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGATCGAGATCAAACAGACCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATTCCAGAGCCAGGGCGTTGATCGC
TGCGCGGATTTTTCGCCTGGCCAATGGCCTTGCCGGTGACGTGCCACCGGTGGGCGAGGGCGTCAGCGAGTTGCGCATCC
ATTACGGGCCGGGCTATCGGGTTTACTTCCAGCAGCTTGGTTCGCAACTCGTCATCCTGTTATGCGGCGGCGACAAGAGT
CGCCAGAGCCGCGATATCGAACTGGCCAAACAGCTGGCCCGTCGTTGGAGCCGATCATGA
ATGATCGAGATCAAACAGACCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATTCCAGAGCCAGGGCGTTGATCGC
TGCGCGGATTTTTCGCCTGGCCAATGGCCTTGCCGGTGACGTGCCACCGGTGGGCGAGGGCGTCAGCGAGTTGCGCATCC
ATTACGGGCCGGGCTATCGGGTTTACTTCCAGCAGCTTGGTTCGCAACTCGTCATCCTGTTATGCGGCGGCGACAAGAGT
CGCCAGAGCCGCGATATCGAACTGGCCAAACAGCTGGCCCGTCGTTGGAGCCGATCATGA
Antitoxin
Download Length: 98 a.a. Molecular weight: 10446.94 Da Isoelectric Point: 5.6558
>AT99979 WP_041987449.1 NZ_CP027720:c6250337-6250044 [Pseudomonas chlororaphis subsp. aureofaciens]
MNEPLFDYDPATSLRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLDMTARVHGAS
MNEPLFDYDPATSLRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLDMTARVHGAS
Download Length: 294 bp
>AT99979 NZ_CP027720:c6250337-6250044 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGAACGAACCGCTATTCGACTATGACCCCGCCACGTCCCTGCGTGACCCGCAGGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCGTTCAGTGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGCGCCCTGGGGCTGGATATGACGGCGCGGGTGCATGGGGCGTCTTGA
ATGAACGAACCGCTATTCGACTATGACCCCGCCACGTCCCTGCGTGACCCGCAGGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCGTTCAGTGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGCGCCCTGGGGCTGGATATGACGGCGCGGGTGCATGGGGCGTCTTGA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A554PHZ9 |
Antitoxin
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Source | ID | Structure |
---|---|---|
No matching records found |