Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6250044..6250633 Replicon chromosome
Accession NZ_CP027720
Organism Pseudomonas chlororaphis subsp. aureofaciens strain DSM 6698

Toxin (Protein)


Gene name PumA Uniprot ID A0A554PHZ9
Locus tag C4K13_RS28420 Protein ID WP_041987451.1
Coordinates 6250334..6250633 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag C4K13_RS28415 Protein ID WP_041987449.1
Coordinates 6250044..6250337 (-) Length 98 a.a.

Genomic Context


C4K13_RS28405C4K13_RS28410C4K13_RS28425C4K13_RS28445C4K13_RS28450C4K13_RS28395C4K13_RS28400C4K13_RS28415C4K13_RS28420C4K13_RS28430C4K13_RS28435C4K13_RS28440
Location: 6248260..6249147 (888 bp)
Type: Others
Protein ID: WP_009051074.1
Location: 6249519..6249911 (393 bp)
Type: Others
Protein ID: WP_009051075.1
Location: 6250804..6251253 (450 bp)
Type: Others
Protein ID: WP_041987453.1
Location: 6254026..6254268 (243 bp)
Type: Others
Protein ID: WP_007924102.1
Location: 6254265..6255152 (888 bp)
Type: Others
Protein ID: WP_009051083.1
Location: 6245585..6246748 (1164 bp)
Type: Others
Protein ID: WP_041987444.1
Location: 6246943..6248133 (1191 bp)
Type: Others
Protein ID: WP_041987447.1
Location: 6250044..6250337 (294 bp)
Type: Antitoxin
Protein ID: WP_041987449.1
Location: 6250334..6250633 (300 bp)
Type: Toxin
Protein ID: WP_041987451.1
Location: 6251278..6252288 (1011 bp)
Type: Others
Protein ID: WP_172833408.1
Location: 6252346..6252645 (300 bp)
Type: Others
Protein ID: WP_009051080.1
Location: 6252709..6253800 (1092 bp)
Type: Others
Protein ID: WP_041987461.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
C4K13_RS283956245585..6246748-1164WP_041987444.1acyltransferase-
C4K13_RS284006246943..6248133-1191WP_041987447.1serine hydrolase-
C4K13_RS284056248260..6249147+888WP_009051074.1LysR family transcriptional regulator-
C4K13_RS284106249519..6249911+393WP_009051075.1hypothetical protein-
C4K13_RS284156250044..6250337-294WP_041987449.1putative addiction module antidote proteinAntitoxin
C4K13_RS284206250334..6250633-300WP_041987451.1type II toxin-antitoxin system RelE/ParE family toxinToxin
C4K13_RS284256250804..6251253+450WP_041987453.1DUF3828 domain-containing protein-
C4K13_RS284306251278..6252288-1011WP_172833408.1NAD(P)-dependent alcohol dehydrogenase-
C4K13_RS284356252346..6252645-300WP_009051080.1ArsR family transcriptional regulator-
C4K13_RS284406252709..6253800-1092WP_041987461.1nitrite reductase, copper-containing-
C4K13_RS284456254026..6254268+243WP_007924102.1exodeoxyribonuclease VII small subunit-
C4K13_RS284506254265..6255152+888WP_009051083.1(2E,6E)-farnesyl diphosphate synthase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 100 a.a.        Molecular weight: 11231.97 Da        Isoelectric Point: 10.6086

>T99979 WP_041987451.1 NZ_CP027720:c6250633-6250334 [Pseudomonas chlororaphis subsp. aureofaciens]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVPPVGEGVSELRIHYGPGYRVYFQQLGSQLVILLCGGDKS
RQSRDIELAKQLARRWSRS

Download         Length: 300 bp

>T99979 NZ_CP027720:c6250633-6250334 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGATCGAGATCAAACAGACCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATTCCAGAGCCAGGGCGTTGATCGC
TGCGCGGATTTTTCGCCTGGCCAATGGCCTTGCCGGTGACGTGCCACCGGTGGGCGAGGGCGTCAGCGAGTTGCGCATCC
ATTACGGGCCGGGCTATCGGGTTTACTTCCAGCAGCTTGGTTCGCAACTCGTCATCCTGTTATGCGGCGGCGACAAGAGT
CGCCAGAGCCGCGATATCGAACTGGCCAAACAGCTGGCCCGTCGTTGGAGCCGATCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10446.94 Da        Isoelectric Point: 5.6558

>AT99979 WP_041987449.1 NZ_CP027720:c6250337-6250044 [Pseudomonas chlororaphis subsp. aureofaciens]
MNEPLFDYDPATSLRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLDMTARVHGAS

Download         Length: 294 bp

>AT99979 NZ_CP027720:c6250337-6250044 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGAACGAACCGCTATTCGACTATGACCCCGCCACGTCCCTGCGTGACCCGCAGGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCGTTCAGTGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGCGCCCTGGGGCTGGATATGACGGCGCGGGTGCATGGGGCGTCTTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A554PHZ9


Antitoxin

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Source
ID
Structure
No matching records found

References