Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6133236..6133825 Replicon chromosome
Accession NZ_CP027718
Organism Pseudomonas chlororaphis subsp. aurantiaca strain Q16

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C4K15_RS27510 Protein ID WP_124337286.1
Coordinates 6133526..6133825 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag C4K15_RS27505 Protein ID WP_028683469.1
Coordinates 6133236..6133529 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K15_RS27485 6128585..6129775 - 1191 WP_124339143.1 serine hydrolase -
C4K15_RS27490 6129902..6130789 + 888 WP_009051074.1 LysR family transcriptional regulator -
C4K15_RS27495 6130971..6131768 - 798 WP_124339144.1 helix-turn-helix transcriptional regulator -
C4K15_RS27500 6131948..6132868 + 921 WP_124339145.1 EamA family transporter -
C4K15_RS27505 6133236..6133529 - 294 WP_028683469.1 putative addiction module antidote protein Antitoxin
C4K15_RS27510 6133526..6133825 - 300 WP_124337286.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K15_RS27515 6133996..6134445 + 450 WP_124339146.1 DUF3828 domain-containing protein -
C4K15_RS27520 6134470..6135480 - 1011 WP_172834887.1 NAD(P)-dependent alcohol dehydrogenase -
C4K15_RS27525 6135538..6135837 - 300 WP_009051080.1 ArsR family transcriptional regulator -
C4K15_RS27530 6135901..6136992 - 1092 WP_124339147.1 nitrite reductase, copper-containing -
C4K15_RS27535 6137218..6137460 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
C4K15_RS27540 6137457..6138344 + 888 WP_038575447.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Uncharacterized protein HI1420

(11-92)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11253.09 Da        Isoelectric Point: 10.1883

>T99965 WP_124337286.1 NZ_CP027718:c6133825-6133526 [Pseudomonas chlororaphis subsp. aurantiaca]
MIEIKQIATFMEWENRLKNSRARALIAAWIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQPCGLQLVILLCGGDKS
RQGRDIELAKYLARRWSRS

Download         Length: 300 bp

>T99965 NZ_CP027718:c6133825-6133526 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGATCGAGATCAAACAGATCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGAATTCCAGAGCCAGGGCGTTGATCGC
TGCGTGGATTTTTCGCCTGGCCAACGGCCTTGCCGGTGACGTGTCCCCGGTGGGCGAAGGCGTCAGTGAGTTGCGCATCC
ATTACGGGCCGGGCTACCGGGTTTACTTCCAGCCGTGCGGCCTGCAACTCGTCATCCTGTTATGCGGCGGCGACAAGAGT
CGCCAGGGCCGCGATATCGAACTGGCCAAATACCTGGCCCGTCGTTGGAGTCGATCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10444.96 Da        Isoelectric Point: 5.6642

>AT99965 WP_028683469.1 NZ_CP027718:c6133529-6133236 [Pseudomonas chlororaphis subsp. aurantiaca]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLEMTARVHGAS

Download         Length: 294 bp

>AT99965 NZ_CP027718:c6133529-6133236 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGAACGAACCGCTATTCGACTATGACCCCGCCACGGCCTTGCGCGACCCGCAAGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCGTTCAGTGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGCGCCCTGGGGCTGGAGATGACGGCGCGGGTGCATGGGGCGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References