99959

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6073364..6073953 Replicon chromosome
Accession NZ_CP027717
Organism Pseudomonas chlororaphis subsp. aurantiaca strain PCM 2210

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C4K16_RS27360 Protein ID WP_124337286.1
Coordinates 6073654..6073953 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag C4K16_RS27355 Protein ID WP_124337285.1
Coordinates 6073364..6073657 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K16_RS27335 6068713..6069903 - 1191 WP_124309654.1 serine hydrolase -
C4K16_RS27340 6070030..6070917 + 888 WP_009051074.1 LysR family transcriptional regulator -
C4K16_RS27345 6071095..6071892 - 798 WP_124337283.1 helix-turn-helix transcriptional regulator -
C4K16_RS27350 6072072..6072992 + 921 WP_124337284.1 EamA family transporter -
C4K16_RS27355 6073364..6073657 - 294 WP_124337285.1 putative addiction module antidote protein Antitoxin
C4K16_RS27360 6073654..6073953 - 300 WP_124337286.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K16_RS27365 6074126..6074575 + 450 WP_081359640.1 DUF3828 domain-containing protein -
C4K16_RS27370 6074600..6075610 - 1011 WP_172834887.1 NAD(P)-dependent alcohol dehydrogenase -
C4K16_RS27375 6075668..6075967 - 300 WP_009051080.1 ArsR family transcriptional regulator -
C4K16_RS27380 6076029..6077120 - 1092 WP_124337287.1 nitrite reductase, copper-containing -
C4K16_RS27385 6077381..6077623 - 243 WP_124337288.1 hypothetical protein -
C4K16_RS27390 6078109..6078351 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Uncharacterized protein HI1420

(6-91)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11253.09 Da        Isoelectric Point: 10.1883

>T99959 WP_124337286.1 NZ_CP027717:c6073953-6073654 [Pseudomonas chlororaphis subsp. aurantiaca]
MIEIKQIATFMEWENRLKNSRARALIAAWIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQPCGLQLVILLCGGDKS
RQGRDIELAKYLARRWSRS

Download         Length: 300 bp

>T99959 NZ_CP027717:c6073953-6073654 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGATCGAGATCAAACAGATCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGAATTCCAGAGCCAGGGCGTTGATCGC
TGCGTGGATTTTTCGCCTGGCCAACGGCCTTGCCGGTGACGTGTCCCCGGTGGGCGAAGGCGTCAGTGAGTTGCGCATCC
ATTACGGGCCGGGCTACCGGGTTTACTTCCAGCCGTGCGGCCTGCAACTCGTCATCCTGTTATGCGGCGGCGACAAGAGT
CGCCAGGGCCGCGATATCGAACTGGCCAAATACCTGGCCCGTCGTTGGAGTCGATCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10525.05 Da        Isoelectric Point: 6.2163

>AT99959 WP_124337285.1 NZ_CP027717:c6073657-6073364 [Pseudomonas chlororaphis subsp. aurantiaca]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMHALGLEMTARVHRAS

Download         Length: 294 bp

>AT99959 NZ_CP027717:c6073657-6073364 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGAACGAACCGCTATTCGACTATGACCCCGCCACGGCCTTGCGCGACCCGCAAGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCGTTCAGTGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCACGCCCTGGGGCTGGAGATGACGGCGCGGGTGCACAGGGCGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References