Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 5859147..5859736 Replicon chromosome
Accession NZ_CP027716
Organism Pseudomonas chlororaphis strain Pb-St2

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C4K23_RS26400 Protein ID WP_023969316.1
Coordinates 5859437..5859736 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag C4K23_RS26395 Protein ID WP_007924096.1
Coordinates 5859147..5859440 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K23_RS26370 5854687..5855850 - 1164 WP_023969313.1 acyltransferase -
C4K23_RS26375 5856045..5857235 - 1191 WP_023969314.1 serine hydrolase -
C4K23_RS26380 5857362..5858249 + 888 WP_009051074.1 LysR family transcriptional regulator -
C4K23_RS26390 5858621..5859013 + 393 WP_023969315.1 hypothetical protein -
C4K23_RS26395 5859147..5859440 - 294 WP_007924096.1 putative addiction module antidote protein Antitoxin
C4K23_RS26400 5859437..5859736 - 300 WP_023969316.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K23_RS26405 5859908..5860357 + 450 WP_023969317.1 DUF3828 domain-containing protein -
C4K23_RS26410 5860382..5861392 - 1011 WP_193725262.1 NAD(P)-dependent alcohol dehydrogenase -
C4K23_RS26415 5861448..5861747 - 300 WP_009051080.1 ArsR family transcriptional regulator -
C4K23_RS26420 5861809..5862900 - 1092 WP_023969319.1 nitrite reductase, copper-containing -
C4K23_RS26425 5863126..5863368 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
C4K23_RS26430 5863365..5864252 + 888 WP_023969320.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(6-91)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11104.77 Da        Isoelectric Point: 10.3417

>T99953 WP_023969316.1 NZ_CP027716:c5859736-5859437 [Pseudomonas chlororaphis]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYVQQLGSQLVILLCGGDKS
RQSRDIELAKQLARSWSRS

Download         Length: 300 bp

>T99953 NZ_CP027716:c5859736-5859437 [Pseudomonas chlororaphis]
ATGATCGAGATCAAACAGACCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATTCCAGAGCCAGGGCGTTGATCGC
TGCGCGGATTTTTCGCCTGGCCAACGGCCTTGCCGGGGACGTGTCACCGGTGGGCGAGGGCGTCAGCGAGCTGCGCATCC
ATTACGGGCCGGGCTACCGGGTTTACGTCCAGCAGCTCGGTTCGCAACTCGTCATCCTGTTGTGCGGCGGCGACAAGAGT
CGCCAGAGCCGCGATATCGAACTGGCCAAACAGTTGGCCCGCAGTTGGAGCCGATCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10430.94 Da        Isoelectric Point: 5.6558

>AT99953 WP_007924096.1 NZ_CP027716:c5859440-5859147 [Pseudomonas chlororaphis]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLDMTARVHGAS

Download         Length: 294 bp

>AT99953 NZ_CP027716:c5859440-5859147 [Pseudomonas chlororaphis]
ATGAACGAACCGCTATTCGACTATGACCCCGCCACGGCCTTGCGCGACCCGCAGGCCATCGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTAGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCGTTCAGCGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGCGCCCTGGGGCTGGACATGACGGCGCGGGTGCATGGGGCGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References