Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 5964874..5965463 Replicon chromosome
Accession NZ_CP027715
Organism Pseudomonas chlororaphis subsp. aurantiaca strain M12

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C4K24_RS26985 Protein ID WP_124309656.1
Coordinates 5965164..5965463 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag C4K24_RS26980 Protein ID WP_028683469.1
Coordinates 5964874..5965167 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K24_RS26960 5960436..5961599 - 1164 WP_124309653.1 acyltransferase -
C4K24_RS26965 5961794..5962984 - 1191 WP_124309654.1 serine hydrolase -
C4K24_RS26970 5963111..5963998 + 888 WP_009051074.1 LysR family transcriptional regulator -
C4K24_RS26975 5964386..5964778 + 393 WP_124309655.1 hypothetical protein -
C4K24_RS26980 5964874..5965167 - 294 WP_028683469.1 putative addiction module antidote protein Antitoxin
C4K24_RS26985 5965164..5965463 - 300 WP_124309656.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K24_RS26990 5965634..5966083 + 450 WP_124309657.1 DUF3828 domain-containing protein -
C4K24_RS26995 5966108..5967118 - 1011 WP_172834887.1 NAD(P)-dependent alcohol dehydrogenase -
C4K24_RS27000 5967176..5967475 - 300 WP_124309658.1 ArsR family transcriptional regulator -
C4K24_RS27005 5967539..5968630 - 1092 WP_124309659.1 nitrite reductase, copper-containing -
C4K24_RS27010 5968856..5969098 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
C4K24_RS27015 5969095..5969982 + 888 WP_038575447.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Uncharacterized protein HI1420

(11-92)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11233.00 Da        Isoelectric Point: 10.6119

>T99949 WP_124309656.1 NZ_CP027715:c5965463-5965164 [Pseudomonas chlororaphis subsp. aurantiaca]
MIEIKQIATFMEWENRLKNSRARALIAAWIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQQLGSQLVILLCGGDKS
RQGRDIELAKQLARRWSRS

Download         Length: 300 bp

>T99949 NZ_CP027715:c5965463-5965164 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGATCGAGATCAAACAGATCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGAATTCCAGAGCCAGGGCGTTGATCGC
TGCGTGGATTTTTCGCCTGGCCAACGGCCTTGCCGGTGACGTGTCCCCGGTGGGCGAAGGCGTCAGCGAGCTGCGCATCC
ATTACGGGCCGGGCTACCGGGTTTACTTCCAGCAGCTTGGTTCGCAACTCGTCATCCTGTTATGCGGCGGCGACAAGAGT
CGCCAGGGCCGCGATATCGAACTGGCCAAACAGCTGGCCCGTCGTTGGAGCCGATCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10444.96 Da        Isoelectric Point: 5.6642

>AT99949 WP_028683469.1 NZ_CP027715:c5965167-5964874 [Pseudomonas chlororaphis subsp. aurantiaca]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLEMTARVHGAS

Download         Length: 294 bp

>AT99949 NZ_CP027715:c5965167-5964874 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGAACGAACCGCTATTCGACTATGACCCCGCCACGGCCTTGCGCGACCCGCAAGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCGTTCAGTGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGCGCCCTGGGGCTGGAGATGACGGCGCGGGTGCATGGGGCGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References