Detailed information of TA system TA099939

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 981241..981779
• Replicon: chromosome
• Accession: NZ_CP027714
• Organism: Pseudomonas chlororaphis strain ATCC 17415

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C4K25_RS04315
• Protein ID: WP_114760040.1
• Coordinates: 981501..981779 (+)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C4K25_RS04310
• Protein ID: WP_009042148.1
• Coordinates: 981241..981504 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C4K25_RS04295	977231..979504	-	2274	WP_114760042.1	TonB-dependent siderophore receptor	-
C4K25_RS04300	979710..980390	+	681	WP_009042146.1	Fe2+-dependent dioxygenase	-
C4K25_RS04305	980394..981179	+	786	WP_114760041.1	sel1 repeat family protein	-
C4K25_RS04310	981241..981504	+	264	WP_009042148.1	ribbon-helix-helix domain-containing protein	Antitoxin
C4K25_RS04315	981501..981779	+	279	WP_114760040.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C4K25_RS04320	981854..983017	-	1164	WP_009042150.1	type III PLP-dependent enzyme	-
C4K25_RS04325	983570..984727	-	1158	WP_062823682.1	ABC transporter ATP-binding protein	-
C4K25_RS04330	984724..985377	-	654	WP_007923833.1	ABC transporter permease	-
C4K25_RS04335	985392..986285	-	894	WP_114760039.1	glycine betaine ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-89)

Antitoxin

• Ribbon-helix-helix protein, CopG (7-44)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10781.39 Da
• Isoelectric Point: 9.6923

>T99939 WP_114760040.1 NZ_CP027714:981501-981779 [Pseudomonas chlororaphis]
VRELKWTSKALSDLARLFEFLAPVNRSVAARTVQSLTQAPDTLLTNPRIGEQLEEFQPRDVRRLLVGPYEMRYEIQDATL
YILRVWHVRGDR

Nucleotide

• Length: 279 bp

>T99939 NZ_CP027714:981501-981779 [Pseudomonas chlororaphis]
GTGAGGGAATTGAAATGGACGAGCAAGGCACTGTCGGACCTGGCCCGACTGTTTGAGTTTCTTGCTCCGGTGAACCGTTC
GGTGGCAGCTCGAACTGTGCAATCGCTCACGCAGGCCCCGGATACCCTGCTGACCAATCCGCGTATCGGCGAACAGTTGG
AGGAGTTTCAGCCTCGCGATGTTCGGCGTTTATTGGTCGGGCCTTACGAGATGCGTTACGAGATCCAGGATGCGACGCTC
TACATCCTGCGGGTGTGGCATGTACGAGGAGACCGCTAG

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9768.17 Da
• Isoelectric Point: 5.6088

>AT99939 WP_009042148.1 NZ_CP027714:981241-981504 [Pseudomonas chlororaphis]
MTATKVLTAHVPLELADKVDQMASRLERSRGWIVKQALVAWVDQEEERSRLTHEALADVDAGRVIDHQAVQAWAESLMND
KPLPVPK

Nucleotide

• Length: 264 bp

>AT99939 NZ_CP027714:981241-981504 [Pseudomonas chlororaphis]
ATGACCGCAACTAAAGTGCTGACCGCACATGTGCCGTTGGAGTTGGCCGACAAGGTCGACCAGATGGCCTCCCGGCTGGA
GCGCTCGCGCGGCTGGATCGTCAAGCAGGCTCTGGTGGCGTGGGTCGATCAGGAAGAGGAGCGCAGTCGCCTGACCCATG
AGGCTTTGGCCGATGTGGATGCTGGGCGGGTCATCGATCACCAGGCGGTCCAGGCATGGGCCGAGAGCCTGATGAATGAC
AAGCCTTTGCCGGTGCCCAAGTGA