Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 6564628..6566336 Replicon chromosome
Accession NZ_CP027713
Organism Pseudomonas chlororaphis strain TAMOak81

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag C4K26_RS30015 Protein ID WP_124353149.1
Coordinates 6564628..6565506 (+) Length 293 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag C4K26_RS30020 Protein ID WP_124353150.1
Coordinates 6565503..6566336 (+) Length 278 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K26_RS29990 6560618..6561469 + 852 WP_124353144.1 ABC transporter ATP-binding protein -
C4K26_RS29995 6561509..6562501 + 993 WP_124353145.1 ABC transporter substrate-binding protein -
C4K26_RS30000 6562530..6563306 + 777 WP_124353146.1 ABC transporter permease -
C4K26_RS30005 6563306..6564070 + 765 WP_124353147.1 SDR family oxidoreductase -
C4K26_RS30010 6564084..6564623 + 540 WP_124353148.1 cupin domain-containing protein -
C4K26_RS30015 6564628..6565506 + 879 WP_124353149.1 alpha/beta hydrolase Toxin
C4K26_RS30020 6565503..6566336 + 834 WP_124353150.1 IclR family transcriptional regulator Antitoxin
C4K26_RS30025 6566338..6567135 + 798 WP_124353151.1 SDR family oxidoreductase -
C4K26_RS30030 6567128..6568810 + 1683 WP_124353152.1 thiamine pyrophosphate-binding protein -
C4K26_RS30035 6568821..6569624 + 804 WP_124353153.1 aspartate dehydrogenase -
C4K26_RS30040 6569636..6571132 + 1497 WP_124353154.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(45-276)

Antitoxin

Transcription regulator IclR, N-terminal

(19-68)


Sequences

Toxin        


Download         Length: 293 a.a.        Molecular weight: 30921.48 Da        Isoelectric Point: 7.0753

>T99935 WP_124353149.1 NZ_CP027713:6564628-6565506 [Pseudomonas chlororaphis]
MLPGLSQPVATADLQARLARDFVQRLVPVAGGQQALRECGAGPAIVLLHGIGSGAASWLEVARQLAPQARVIAWDAPGYG
DSSPLESPAPKAEQYAARLVQMLDALDVEECVLVGHSLGALPALAFARSSQASRVSRLVLISPARGYGAPERGEQRQQVR
RQRLENLEHLGIAGLAEQRSAHMLSPNAAPQALAWVRWNMARLNPAGYRQAIELLCGDDLLRHGQPGMPCEVHCGEADRI
TPAETCLTLAKALGASFNLIADAGHASPIEQPLVVAGRLAFAIKESLTGTTL

Download         Length: 879 bp

>T99935 NZ_CP027713:6564628-6565506 [Pseudomonas chlororaphis]
ATGTTGCCAGGCCTCTCTCAACCCGTAGCGACGGCGGACCTGCAAGCCCGACTGGCCCGCGACTTTGTCCAGCGCCTAGT
GCCCGTCGCCGGCGGCCAACAGGCCCTGCGCGAATGCGGCGCGGGCCCGGCGATCGTGCTGCTGCACGGCATCGGTTCCG
GGGCGGCGTCCTGGCTAGAGGTGGCCCGACAGCTGGCGCCCCAGGCCCGGGTCATCGCCTGGGACGCGCCCGGCTACGGC
GATTCCAGCCCCCTGGAATCCCCCGCGCCCAAGGCCGAGCAGTACGCCGCGCGCCTGGTGCAGATGCTCGATGCGCTGGA
CGTCGAGGAATGCGTGCTGGTCGGGCATTCCCTCGGCGCCCTGCCGGCCCTGGCCTTCGCCCGCAGCTCACAGGCGAGCC
GGGTGAGTCGCCTGGTACTGATCAGCCCGGCGCGGGGTTATGGCGCGCCGGAACGCGGCGAGCAGCGCCAGCAGGTGCGC
CGCCAGCGCCTGGAGAACCTGGAACACCTGGGGATCGCCGGCCTGGCCGAACAGCGCAGCGCCCACATGCTCTCGCCCAA
CGCCGCGCCGCAGGCCCTGGCCTGGGTGCGCTGGAACATGGCGCGGCTCAACCCCGCGGGTTATCGCCAGGCCATCGAGC
TGCTATGCGGCGACGACCTGCTGCGCCACGGCCAGCCCGGCATGCCCTGCGAAGTGCATTGCGGCGAAGCCGACCGCATC
ACCCCGGCCGAGACCTGCCTGACCCTGGCCAAGGCGCTGGGCGCCAGCTTCAACCTGATCGCCGACGCGGGCCACGCCAG
CCCCATCGAACAACCGCTGGTGGTCGCGGGCCGCCTGGCCTTTGCCATCAAAGAATCCCTGACAGGTACAACCCTATGA

Antitoxin


Download         Length: 278 a.a.        Molecular weight: 30829.25 Da        Isoelectric Point: 6.7591

>AT99935 WP_124353150.1 NZ_CP027713:6565503-6566336 [Pseudomonas chlororaphis]
MNDSDPLKDAQDKYIVPGLERGLLLLCEFSRRNRTLTAPELARRLALPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRLNYPSNLVVRDGRSIVYVAKVSPPSVFSNAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEEHLEQHSHSTPKTVLELFDMVQADRQRGFVSGEGFFESAISTVAAPVRDQSGRIAAALGVTIPTTQIGHVNF
EELLSQVRRSADELSRLLNYNGVAHDGQQRVTALMRD

Download         Length: 834 bp

>AT99935 NZ_CP027713:6565503-6566336 [Pseudomonas chlororaphis]
ATGAACGACTCCGATCCGCTGAAGGACGCTCAGGACAAATACATCGTGCCGGGCCTGGAGCGTGGCCTGTTGCTGCTCTG
CGAGTTCAGCCGGCGCAACCGCACCCTGACCGCGCCGGAACTGGCCCGCCGCCTGGCCTTGCCGCGCTCGACCATTTTCC
GCCTGCTCACCACCCTGGAAACCATGGGTTTCGTCACCCGCAGCGGCAACGAATACCGCCTCGGCATGTCGGTGCTGCGC
CTGGGCTTCGAGTACCTGGCGTCGCTGGAGCTGACCGAACTCGGCCAGCCGCTGCTGGCGCGCCTGTGCGACCGCCTCAA
CTACCCGAGCAACCTGGTGGTGCGCGACGGCCGCTCGATCGTCTACGTGGCCAAGGTCTCGCCGCCGTCGGTGTTCTCCA
ACGCGGTCAACGTCGGCACCCGCCTGCCGGCCCACGCCACGGTGCTGGGGCGCATCCTCCTGGAGGACCTGTCGCTGGCC
GAACTGCGCGAGCTGTACCCCGAAGAGCACCTGGAGCAGCACTCCCACAGCACGCCGAAAACCGTGCTGGAGCTGTTCGA
CATGGTCCAGGCCGACCGCCAGCGCGGCTTTGTCAGCGGCGAAGGTTTCTTCGAGTCGGCGATCTCCACCGTGGCCGCGC
CGGTGCGCGACCAGAGCGGGCGCATCGCCGCGGCCCTGGGCGTGACCATCCCCACCACGCAGATCGGCCACGTCAATTTC
GAGGAACTGCTGTCGCAGGTCCGCCGCAGCGCCGACGAGCTGTCGCGCCTGCTCAACTACAACGGCGTGGCCCACGACGG
GCAACAGCGCGTGACCGCCTTGATGAGGGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References