Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4028505..4029024 Replicon chromosome
Accession NZ_CP027713
Organism Pseudomonas chlororaphis strain TAMOak81

Toxin (Protein)


Gene name relE Uniprot ID A0A1H3UB31
Locus tag C4K26_RS18150 Protein ID WP_007930524.1
Coordinates 4028505..4028786 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3G7HDX0
Locus tag C4K26_RS18155 Protein ID WP_007930518.1
Coordinates 4028776..4029024 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K26_RS18130 4024996..4025268 + 273 WP_124351555.1 hypothetical protein -
C4K26_RS18140 4026134..4026616 + 483 WP_009044429.1 acyl-CoA thioesterase -
C4K26_RS18145 4026669..4028318 + 1650 WP_124351556.1 FMN-binding glutamate synthase family protein -
C4K26_RS18150 4028505..4028786 - 282 WP_007930524.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K26_RS18155 4028776..4029024 - 249 WP_007930518.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C4K26_RS18160 4029120..4029908 - 789 WP_124351557.1 helix-turn-helix transcriptional regulator -
C4K26_RS18165 4029993..4030991 + 999 WP_124351558.1 bile acid:sodium symporter -
C4K26_RS18170 4031123..4031866 - 744 WP_124351559.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4020610..4034082 13472


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10890.73 Da        Isoelectric Point: 10.6993

>T99934 WP_007930524.1 NZ_CP027713:c4028786-4028505 [Pseudomonas chlororaphis]
MTYELEFSEKAWKEWQKLGPTLKEQFKKKLQERLVNPHVPADRLSGLGNAYKIKLRTAGYRLVYRVVDEVLVVTVIAVGK
RERGSVYQQARKR

Download         Length: 282 bp

>T99934 NZ_CP027713:c4028786-4028505 [Pseudomonas chlororaphis]
ATGACTTATGAGCTGGAGTTCTCCGAGAAAGCCTGGAAGGAATGGCAAAAGCTGGGCCCCACGCTGAAAGAGCAATTCAA
GAAGAAGCTGCAGGAACGCCTCGTCAACCCCCATGTCCCGGCCGATCGCCTGAGCGGTTTGGGCAATGCCTACAAAATCA
AACTGCGCACGGCTGGCTACCGTCTGGTGTATCGGGTGGTGGATGAGGTGTTGGTGGTGACGGTCATTGCTGTGGGCAAG
CGGGAGCGGGGGAGTGTCTATCAGCAAGCCAGGAAGCGTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9011.36 Da        Isoelectric Point: 4.4142

>AT99934 WP_007930518.1 NZ_CP027713:c4029024-4028776 [Pseudomonas chlororaphis]
MTHVLLSNVVASISELKKNPMGTVAAGGGSSVAILNRNEPAFYCVPAKEYEAMMERLEDMELLALCRERENDPTVRVSLD
DL

Download         Length: 249 bp

>AT99934 NZ_CP027713:c4029024-4028776 [Pseudomonas chlororaphis]
ATGACCCATGTCCTTCTGTCCAACGTCGTTGCGAGCATTTCCGAACTCAAGAAAAACCCCATGGGCACTGTTGCGGCCGG
TGGCGGCTCCTCCGTGGCCATTCTCAATCGCAACGAACCGGCGTTTTACTGCGTTCCGGCCAAGGAATACGAAGCCATGA
TGGAGCGCCTGGAAGACATGGAACTGCTCGCCTTGTGCCGTGAGCGAGAGAACGACCCGACCGTCAGGGTTTCGCTCGAT
GACTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H3UB31

Antitoxin

Source ID Structure
AlphaFold DB A0A3G7HDX0

References