Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 349504..350174 Replicon chromosome
Accession NZ_CP027713
Organism Pseudomonas chlororaphis strain TAMOak81

Toxin (Protein)


Gene name vapC Uniprot ID A0A2N8BIG9
Locus tag C4K26_RS01540 Protein ID WP_007925281.1
Coordinates 349504..349932 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A285EZ12
Locus tag C4K26_RS01545 Protein ID WP_007925278.1
Coordinates 349929..350174 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K26_RS01515 346217..346474 - 258 WP_124349083.1 hypothetical protein -
C4K26_RS01520 346769..347509 - 741 WP_124349084.1 SDR family oxidoreductase -
C4K26_RS01525 347648..348538 + 891 WP_124349085.1 LysR family transcriptional regulator -
C4K26_RS01530 348542..348679 + 138 Protein_295 type II toxin-antitoxin system HicB family antitoxin -
C4K26_RS01535 349042..349374 + 333 Protein_296 aldo/keto reductase -
C4K26_RS01540 349504..349932 - 429 WP_007925281.1 type II toxin-antitoxin system VapC family toxin Toxin
C4K26_RS01545 349929..350174 - 246 WP_007925278.1 hypothetical protein Antitoxin
C4K26_RS01550 350302..351141 - 840 WP_124349086.1 taurine dioxygenase -
C4K26_RS01555 351319..352158 - 840 WP_124349087.1 taurine ABC transporter permease TauC -
C4K26_RS01560 352155..352949 - 795 WP_124349088.1 taurine ABC transporter ATP-binding subunit -
C4K26_RS01565 353045..354022 - 978 WP_124349089.1 taurine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15825.45 Da        Isoelectric Point: 5.4927

>T99932 WP_007925281.1 NZ_CP027713:c349932-349504 [Pseudomonas chlororaphis]
MIVLDTNVLSELMRPQPDASVLLWIEAQPVEDLYISAMTMAEILHGIARLPHGKRKQMLHASALAMFEEDFIDRIVPFGT
QAALYYAHLISHRESLGRPISLVDAQIAAICRVHDAAIATRNAKDFSDTGLIVINPWLPLEI

Download         Length: 429 bp

>T99932 NZ_CP027713:c349932-349504 [Pseudomonas chlororaphis]
ATGATCGTGCTCGACACCAATGTGCTGTCGGAACTGATGCGTCCCCAGCCGGACGCATCGGTATTGCTGTGGATCGAAGC
GCAACCTGTCGAAGACCTCTACATCAGCGCCATGACCATGGCCGAGATTCTTCACGGCATCGCGCGCCTGCCCCACGGCA
AGCGCAAACAGATGCTCCATGCGTCGGCGCTGGCGATGTTCGAGGAAGATTTCATCGACCGCATCGTGCCCTTCGGGACC
CAGGCGGCTCTTTACTACGCCCATCTGATTTCGCACCGGGAAAGCCTGGGGCGTCCGATCAGCCTGGTGGATGCGCAAAT
TGCGGCCATATGCCGCGTCCACGACGCGGCTATCGCCACCCGTAACGCCAAGGATTTCAGCGACACCGGGTTGATCGTTA
TCAACCCCTGGCTGCCACTCGAAATCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9072.30 Da        Isoelectric Point: 7.3226

>AT99932 WP_007925278.1 NZ_CP027713:c350174-349929 [Pseudomonas chlororaphis]
MASLTIRNLDDHIKERLRIEAAHNGHSMEEEARLILRRALSRTADSQGLASRIRARFAEAGGVKLELPERTEPARVVDLG
E

Download         Length: 246 bp

>AT99932 NZ_CP027713:c350174-349929 [Pseudomonas chlororaphis]
ATGGCCAGCCTGACAATCCGAAACCTGGACGACCACATCAAAGAGCGCCTGCGCATCGAGGCCGCCCACAACGGCCACTC
CATGGAAGAAGAAGCCCGCTTGATTTTGCGCCGCGCCCTGAGCAGAACAGCCGACAGCCAAGGCCTGGCCAGTCGTATCC
GGGCACGCTTTGCCGAGGCCGGCGGAGTGAAGCTTGAGCTGCCCGAACGTACCGAGCCGGCACGCGTGGTGGATCTGGGC
GAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2N8BIG9

Antitoxin

Source ID Structure
AlphaFold DB A0A285EZ12

References