Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6037971..6038560 Replicon chromosome
Accession NZ_CP027712
Organism Pseudomonas chlororaphis subsp. chlororaphis strain DSM 50083

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C4K27_RS27445 Protein ID WP_007924097.1
Coordinates 6038261..6038560 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag C4K27_RS27440 Protein ID WP_009045810.1
Coordinates 6037971..6038264 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K27_RS27415 6033686..6034144 + 459 WP_053262808.1 GNAT family N-acetyltransferase -
C4K27_RS27420 6034398..6035054 + 657 WP_007924093.1 DedA family protein -
C4K27_RS27425 6035060..6035869 + 810 WP_053262809.1 zinc-dependent peptidase -
C4K27_RS27430 6036134..6036661 + 528 WP_003228599.1 inorganic diphosphatase -
C4K27_RS27435 6037469..6037855 + 387 WP_053262810.1 hypothetical protein -
C4K27_RS27440 6037971..6038264 - 294 WP_009045810.1 putative addiction module antidote protein Antitoxin
C4K27_RS27445 6038261..6038560 - 300 WP_007924097.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K27_RS27450 6038732..6039181 + 450 WP_053262811.1 DUF3828 domain-containing protein -
C4K27_RS27455 6039206..6040216 - 1011 WP_173613368.1 NAD(P)-dependent alcohol dehydrogenase -
C4K27_RS27460 6040274..6040573 - 300 WP_007924100.1 ArsR family transcriptional regulator -
C4K27_RS27465 6040640..6041728 - 1089 WP_053262813.1 nitrite reductase, copper-containing -
C4K27_RS27470 6041955..6042197 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
C4K27_RS27475 6042194..6043081 + 888 WP_053262814.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(47-90)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11326.08 Da        Isoelectric Point: 10.6613

>T99931 WP_007924097.1 NZ_CP027712:c6038560-6038261 [Pseudomonas chlororaphis subsp. chlororaphis]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQQRGLQLVILLCGGDKS
RQSRDIELAKYLARRWSRS

Download         Length: 300 bp

>T99931 NZ_CP027712:c6038560-6038261 [Pseudomonas chlororaphis subsp. chlororaphis]
ATGATCGAGATCAAACAGACCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATTCCAGAGCCAGGGCGTTGATTGC
TGCGCGGATTTTTCGCCTGGCCAACGGTCTTGCCGGGGACGTGTCCCCGGTGGGCGAAGGCGTCAGCGAGTTGCGCATCC
ATTACGGGCCGGGCTACCGGGTTTACTTCCAGCAGCGCGGCTTGCAACTCGTCATCCTGTTGTGCGGCGGCGACAAGAGT
CGCCAGAGCCGCGATATCGAACTGGCCAAATACCTGGCCCGTCGTTGGAGCCGATCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10444.96 Da        Isoelectric Point: 5.6642

>AT99931 WP_009045810.1 NZ_CP027712:c6038264-6037971 [Pseudomonas chlororaphis subsp. chlororaphis]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSEKGNPTLKTLLA
VMRALGLDMTARVHGAS

Download         Length: 294 bp

>AT99931 NZ_CP027712:c6038264-6037971 [Pseudomonas chlororaphis subsp. chlororaphis]
ATGAACGAACCGCTATTCGACTATGACCCCGCCACGGCCTTGCGCGACCCGCAAGCCATCGCCCTGTTCATGGCGGACGC
CTTCGAAACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGTGTGGTGGCGCGGGCCAAGGGCATGACTGAGCTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTATCGCTCATTCAGCGAAAAAGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGTGCACTGGGACTGGACATGACGGCGCGGGTGCATGGGGCGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References