Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2419612..2420197 Replicon chromosome
Accession NZ_CP027712
Organism Pseudomonas chlororaphis subsp. chlororaphis strain DSM 50083

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C4K27_RS11230 Protein ID WP_053260473.1
Coordinates 2419904..2420197 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag C4K27_RS11225 Protein ID WP_053260472.1
Coordinates 2419612..2419902 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K27_RS11215 2417127..2418509 + 1383 WP_053260470.1 efflux transporter outer membrane subunit -
C4K27_RS11220 2418628..2419215 + 588 WP_053260471.1 hypothetical protein -
C4K27_RS11225 2419612..2419902 - 291 WP_053260472.1 putative addiction module antidote protein Antitoxin
C4K27_RS11230 2419904..2420197 - 294 WP_053260473.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K27_RS11235 2420432..2421826 - 1395 WP_053260474.1 VOC family protein -
C4K27_RS11240 2422090..2423214 + 1125 WP_053260475.1 diguanylate cyclase -
C4K27_RS11245 2423308..2424552 + 1245 WP_053260476.1 M20/M25/M40 family metallo-hydrolase -
C4K27_RS11250 2424785..2425180 + 396 WP_007932579.1 carboxymuconolactone decarboxylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-97)

Antitoxin

Uncharacterized protein HI1420

(9-94)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10846.56 Da        Isoelectric Point: 10.5107

>T99930 WP_053260473.1 NZ_CP027712:c2420197-2419904 [Pseudomonas chlororaphis subsp. chlororaphis]
MNYEILQTTVFARWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNMGAGYRLYFTVRGNTLIVLLLGGDK
STQPADICQARYLAKEF

Download         Length: 294 bp

>T99930 NZ_CP027712:c2420197-2419904 [Pseudomonas chlororaphis subsp. chlororaphis]
ATGAATTACGAGATCCTGCAGACGACCGTCTTTGCCCGATGGCACACCACACTACGGGACCTGCGCGCCAGGATAGCCAT
CGCTCGGCGTATCGAGCGGGCTTCGGCGGGCAACCTGGGCGATGTGAAAAACCTCGGCGGCGGTCTCTCGGAAATGCGCG
TGAATATGGGCGCCGGCTACCGCCTCTATTTCACGGTTCGCGGCAATACGCTGATCGTCCTGCTGCTGGGCGGCGACAAG
TCCACCCAGCCTGCCGATATCTGCCAGGCCCGTTACCTGGCCAAGGAGTTCTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10197.74 Da        Isoelectric Point: 8.0096

>AT99930 WP_053260472.1 NZ_CP027712:c2419902-2419612 [Pseudomonas chlororaphis subsp. chlororaphis]
MSDTLLAFDIAALLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVSRG

Download         Length: 291 bp

>AT99930 NZ_CP027712:c2419902-2419612 [Pseudomonas chlororaphis subsp. chlororaphis]
ATGTCCGACACACTGCTTGCCTTCGACATCGCCGCCCTGCTCGACAGCGACCAGGCGATCAGCGAATACCTGTCCCAGGT
CCTGGCCGATGGCGATACCGATGAACTGATCCGCGCCCTGGGCCATGTCGCCAGGGCGCGGGGCATGACGCAGATTGCCA
AGGCCACCGGCCAGGGCCGGGCCAGCCTCTACAAGGCTTTTGCCCCGGGCGCCAAGCCGCGCTTCGATACCGTGGTCAAG
GTCATGCGCGCGCTGGGCCTGCAGCTGTGCACCACCGTGTCCCGAGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References