Detailed information of TA system TA099901

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 313333..314003
• Replicon: chromosome
• Accession: NZ_CP027708
• Organism: Pseudomonas chlororaphis subsp. piscium strain ATCC 17411

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: C4K37_RS01370
• Protein ID: WP_124323278.1
• Coordinates: 313333..313761 (-)
• Length: 143 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A3G7DZE9
• Locus tag: C4K37_RS01375
• Protein ID: WP_009046453.1
• Coordinates: 313758..314003 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C4K37_RS01340	308532..309020	-	489	WP_124323274.1	DoxX family membrane protein	-
C4K37_RS01345	309077..309817	-	741	WP_124323275.1	SDR family oxidoreductase	-
C4K37_RS01350	309947..310837	+	891	WP_124323276.1	LysR family transcriptional regulator	-
C4K37_RS01355	310962..311144	+	183	WP_009041685.1	type II toxin-antitoxin system HicA family toxin	-
C4K37_RS01360	311174..311575	+	402	WP_025808441.1	type II toxin-antitoxin system HicB family antitoxin	-
C4K37_RS01365	312166..313203	+	1038	WP_124323277.1	L-glyceraldehyde 3-phosphate reductase	-
C4K37_RS01370	313333..313761	-	429	WP_124323278.1	type II toxin-antitoxin system VapC family toxin	Toxin
C4K37_RS01375	313758..314003	-	246	WP_009046453.1	plasmid stabilization protein	Antitoxin
C4K37_RS01380	314143..314982	-	840	WP_124323279.1	taurine dioxygenase	-
C4K37_RS01385	315220..316059	-	840	WP_124323280.1	taurine ABC transporter permease TauC	-
C4K37_RS01390	316056..316850	-	795	WP_023970012.1	taurine ABC transporter ATP-binding subunit	-
C4K37_RS01395	316961..317938	-	978	WP_124323281.1	taurine ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-124)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 143 a.a.
• Molecular weight: 15862.37 Da
• Isoelectric Point: 5.4577

>T99901 WP_124323278.1 NZ_CP027708:c313761-313333 [Pseudomonas chlororaphis subsp. piscium]
MIVLDTNVLSELMHPQPDTAVLLWIEAQPVEDLYISAMTMAEILHGIARLPHGKRKQTLHASALAMFEEDFIDRIVPFGT
QAALYYAHLVSHRERSGQPINLVDAQIAAICRVHDAAIATRNTKDFTDTGLIVINPWLPLEI

Nucleotide

• Length: 429 bp

>T99901 NZ_CP027708:c313761-313333 [Pseudomonas chlororaphis subsp. piscium]
ATGATAGTACTCGACACAAATGTGTTGTCAGAACTGATGCACCCTCAACCGGATACGGCGGTATTGCTGTGGATCGAAGC
GCAACCCGTCGAGGACCTCTACATCAGCGCCATGACCATGGCCGAGATTCTCCACGGTATCGCGCGTCTGCCCCACGGCA
AGCGCAAACAGACGCTGCATGCATCGGCGCTGGCCATGTTCGAGGAAGACTTCATCGACCGGATCGTGCCCTTCGGAACC
CAGGCGGCTCTTTACTACGCGCATCTGGTCTCGCATCGCGAAAGATCAGGCCAGCCGATCAACCTGGTGGACGCGCAGAT
TGCAGCGATATGCCGGGTCCATGACGCCGCGATTGCCACCCGCAACACCAAGGATTTCACCGACACTGGGCTGATCGTTA
TCAACCCCTGGCTACCGCTGGAAATCTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9103.27 Da
• Isoelectric Point: 6.2314

>AT99901 WP_009046453.1 NZ_CP027708:c314003-313758 [Pseudomonas chlororaphis subsp. piscium]
MASLTIRNLDDHIKERLRIEAAHNGHSMEEEARLILRRALSRTADSQGLGSRIRARFAETGGVELELPERTEPARLVDLG
E

Nucleotide

• Length: 246 bp

>AT99901 NZ_CP027708:c314003-313758 [Pseudomonas chlororaphis subsp. piscium]
ATGGCCAGCCTTACGATCCGCAATCTGGACGACCACATCAAAGAACGCCTGCGCATCGAGGCCGCTCACAATGGTCATTC
CATGGAAGAAGAAGCCCGATTGATTTTGCGCCGCGCATTGAGCAGGACAGCTGACAGCCAAGGCCTGGGCAGCCGTATCA
GGGCACGCTTTGCCGAGACCGGCGGAGTAGAGTTGGAGCTGCCTGAACGTACCGAACCGGCACGCTTGGTGGACCTGGGC
GAATGA

Structures

Antitoxin

• AlphaFold DB: A0A3G7DZE9