Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2362733..2363318 Replicon chromosome
Accession NZ_CP027707
Organism Pseudomonas chlororaphis subsp. piscium strain DSM 21509

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C4K38_RS11030 Protein ID WP_053278359.1
Coordinates 2363025..2363318 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag C4K38_RS11025 Protein ID WP_053278358.1
Coordinates 2362733..2363023 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K38_RS11010 2358058..2360538 + 2481 WP_053278594.1 FtsX-like permease family protein -
C4K38_RS11015 2360528..2361604 + 1077 WP_053278356.1 iron ABC transporter permease -
C4K38_RS11020 2361732..2362319 + 588 WP_053278357.1 hypothetical protein -
C4K38_RS11025 2362733..2363023 - 291 WP_053278358.1 putative addiction module antidote protein Antitoxin
C4K38_RS11030 2363025..2363318 - 294 WP_053278359.1 addiction module antitoxin RelB Toxin
C4K38_RS11035 2363554..2364948 - 1395 WP_053278360.1 VOC family protein -
C4K38_RS11040 2365211..2366335 + 1125 WP_053278361.1 diguanylate cyclase -
C4K38_RS11045 2366429..2367673 + 1245 WP_053278362.1 M20/M25/M40 family metallo-hydrolase -
C4K38_RS11050 2367881..2368279 + 399 WP_053278363.1 carboxymuconolactone decarboxylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-97)

Antitoxin

Uncharacterized protein HI1420

(8-91)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10812.46 Da        Isoelectric Point: 10.7340

>T99898 WP_053278359.1 NZ_CP027707:c2363318-2363025 [Pseudomonas chlororaphis subsp. piscium]
MDYEIQQTTVFAQWHTRLRDLRARIAIARRIERASAGNLGDVKNLGGGLSQMRVNMGAGYRIYFTVRGNTLIVLLLGGDK
STQPADICQARSLAKEF

Download         Length: 294 bp

>T99898 NZ_CP027707:c2363318-2363025 [Pseudomonas chlororaphis subsp. piscium]
ATGGATTACGAGATCCAGCAGACGACCGTCTTTGCCCAATGGCACACCAGACTACGGGACCTGCGCGCCAGGATAGCCAT
CGCTCGGCGTATCGAGCGGGCTTCGGCGGGCAACCTGGGCGATGTGAAAAACCTCGGCGGCGGTCTCTCGCAAATGCGCG
TGAATATGGGCGCCGGCTACCGCATCTATTTCACGGTTCGCGGCAATACCCTCATCGTCCTGCTGCTGGGCGGCGACAAA
TCCACCCAGCCAGCCGACATCTGCCAGGCTCGTTCCCTGGCCAAGGAGTTCTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10219.79 Da        Isoelectric Point: 8.0096

>AT99898 WP_053278358.1 NZ_CP027707:c2363023-2362733 [Pseudomonas chlororaphis subsp. piscium]
MSDTLVPFDIAALLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVPRG

Download         Length: 291 bp

>AT99898 NZ_CP027707:c2363023-2362733 [Pseudomonas chlororaphis subsp. piscium]
ATGTCCGACACACTGGTTCCCTTCGACATCGCCGCCCTGCTCGACAGTGACCAGGCGATCAGCGAATACCTGTCCCAGGT
CCTGGCCGATGGCGATACCGATGAACTGATCCGCGCCCTGGGCCACGTCGCCAGGGCCCGGGGCATGACGCAGATTGCCA
AGGCCACCGGCCAGGGCCGGGCCAGCCTCTACAAGGCCTTTGCCCCGGGCGCCAAGCCGCGCTTCGATACCGTGGTCAAG
GTCATGCGCGCGCTGGGCCTGCAGCTGTGCACCACAGTGCCCCGTGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References