Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 2817378..2818600 | Replicon | chromosome |
| Accession | NZ_CP027706 | ||
| Organism | Pseudomonas sp. CMR12a | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | C4K39_RS13275 | Protein ID | WP_124346631.1 |
| Coordinates | 2818028..2818600 (+) | Length | 191 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | U6ZMH2 |
| Locus tag | C4K39_RS13270 | Protein ID | WP_022639877.1 |
| Coordinates | 2817378..2817935 (+) | Length | 186 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C4K39_RS13240 | 2812395..2812844 | + | 450 | WP_124348344.1 | ATP-binding protein | - |
| C4K39_RS13245 | 2812914..2813525 | - | 612 | WP_068583852.1 | hypothetical protein | - |
| C4K39_RS13250 | 2813796..2814215 | + | 420 | WP_124346629.1 | helix-turn-helix domain-containing protein | - |
| C4K39_RS13255 | 2814212..2815460 | + | 1249 | Protein_2593 | alpha/beta fold hydrolase | - |
| C4K39_RS13260 | 2815593..2816771 | + | 1179 | WP_124346630.1 | PrpF protein | - |
| C4K39_RS13265 | 2816877..2817206 | - | 330 | WP_022639876.1 | low molecular weight protein tyrosine phosphatase family protein | - |
| C4K39_RS13270 | 2817378..2817935 | + | 558 | WP_022639877.1 | helix-turn-helix domain-containing protein | Antitoxin |
| C4K39_RS13275 | 2818028..2818600 | + | 573 | WP_124346631.1 | HD domain-containing protein | Toxin |
| C4K39_RS13280 | 2818634..2819140 | + | 507 | WP_068583868.1 | N-acetyltransferase | - |
| C4K39_RS13285 | 2819152..2821494 | - | 2343 | WP_124346632.1 | penicillin-binding protein 1A | - |
| C4K39_RS13290 | 2821536..2823458 | - | 1923 | WP_124346633.1 | penicillin-binding protein 2 | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 191 a.a. Molecular weight: 21520.09 Da Isoelectric Point: 5.3042
>T99893 WP_124346631.1 NZ_CP027706:2818028-2818600 [Pseudomonas sp. CMR12a]
MNDQLLGGRLEFLRQAERLKDVLRSAHTSSGRQESTAEHSWRLCLMALLLEDQLGELDLLQVLKLCIVHDLGEALHGDIP
AVQQAAHPDKGQQEREDLQTLASCLDAPARQRLLALWDEYENASSAEAQAVKALDKLETLVQHNQGRNPADFDYRFNLDY
GRRYTSATPLFRALREQIDHDTRRHIDAAG
MNDQLLGGRLEFLRQAERLKDVLRSAHTSSGRQESTAEHSWRLCLMALLLEDQLGELDLLQVLKLCIVHDLGEALHGDIP
AVQQAAHPDKGQQEREDLQTLASCLDAPARQRLLALWDEYENASSAEAQAVKALDKLETLVQHNQGRNPADFDYRFNLDY
GRRYTSATPLFRALREQIDHDTRRHIDAAG
Download Length: 573 bp
>T99893 NZ_CP027706:2818028-2818600 [Pseudomonas sp. CMR12a]
ATGAACGATCAACTCCTCGGTGGTCGCCTCGAATTCCTGCGCCAGGCGGAGCGCCTCAAGGACGTACTGCGCAGTGCCCA
CACCTCCAGCGGTCGCCAGGAAAGCACCGCCGAGCACAGCTGGCGCCTGTGCCTGATGGCCTTGCTGCTGGAAGACCAGC
TGGGCGAGCTGGACCTTTTGCAAGTGCTCAAGCTGTGCATCGTCCACGACCTGGGCGAAGCCCTTCATGGCGACATCCCG
GCGGTGCAGCAGGCGGCCCACCCGGACAAGGGCCAGCAGGAACGCGAAGACCTGCAGACCCTCGCCAGTTGCCTCGATGC
CCCGGCCCGCCAGCGCCTGCTGGCCCTGTGGGACGAATACGAGAATGCCAGCTCGGCCGAGGCCCAGGCGGTCAAGGCCC
TGGATAAGCTGGAGACCCTGGTGCAGCACAACCAGGGGCGTAACCCGGCGGATTTCGATTACCGCTTCAACCTCGACTAC
GGCCGCCGCTACACTAGCGCCACGCCGCTGTTCCGAGCCCTGCGCGAGCAGATCGACCACGACACGCGGCGCCACATCGA
CGCGGCCGGCTGA
ATGAACGATCAACTCCTCGGTGGTCGCCTCGAATTCCTGCGCCAGGCGGAGCGCCTCAAGGACGTACTGCGCAGTGCCCA
CACCTCCAGCGGTCGCCAGGAAAGCACCGCCGAGCACAGCTGGCGCCTGTGCCTGATGGCCTTGCTGCTGGAAGACCAGC
TGGGCGAGCTGGACCTTTTGCAAGTGCTCAAGCTGTGCATCGTCCACGACCTGGGCGAAGCCCTTCATGGCGACATCCCG
GCGGTGCAGCAGGCGGCCCACCCGGACAAGGGCCAGCAGGAACGCGAAGACCTGCAGACCCTCGCCAGTTGCCTCGATGC
CCCGGCCCGCCAGCGCCTGCTGGCCCTGTGGGACGAATACGAGAATGCCAGCTCGGCCGAGGCCCAGGCGGTCAAGGCCC
TGGATAAGCTGGAGACCCTGGTGCAGCACAACCAGGGGCGTAACCCGGCGGATTTCGATTACCGCTTCAACCTCGACTAC
GGCCGCCGCTACACTAGCGCCACGCCGCTGTTCCGAGCCCTGCGCGAGCAGATCGACCACGACACGCGGCGCCACATCGA
CGCGGCCGGCTGA
Antitoxin
Download Length: 186 a.a. Molecular weight: 20413.32 Da Isoelectric Point: 7.0310
>AT99893 WP_022639877.1 NZ_CP027706:2817378-2817935 [Pseudomonas sp. CMR12a]
MSASLFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGQQAMEPSERAKLEQLLAANLSAAADQALARLVND
SPRAVHLVCDLTHRLLACSPTRAGEFGVPLSELLGQSLWGFCTEEIVRKERALDDLGWREVLAPPALEFFSGHNDSAIVP
IAASQCRWTRLNLSDGNAVRLVETL
MSASLFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGQQAMEPSERAKLEQLLAANLSAAADQALARLVND
SPRAVHLVCDLTHRLLACSPTRAGEFGVPLSELLGQSLWGFCTEEIVRKERALDDLGWREVLAPPALEFFSGHNDSAIVP
IAASQCRWTRLNLSDGNAVRLVETL
Download Length: 558 bp
>AT99893 NZ_CP027706:2817378-2817935 [Pseudomonas sp. CMR12a]
ATGTCCGCATCCTTGTTCACTTCCCCGCACCTGGGCCTGGCCCTGCGCCGCTGGCGCCTGCTGCACCGGGTCAAGCAACA
GCACGCCGCCGAGCTGTTCGGGGTGGCGCAGTCGAGCATTTCCCGCTGGGAAAACGGCCAGCAAGCCATGGAACCCAGCG
AGCGCGCCAAGCTGGAGCAACTGCTGGCGGCCAACCTCAGCGCCGCCGCCGACCAGGCCCTGGCCCGGTTGGTGAACGAC
AGCCCGCGGGCGGTGCACCTGGTCTGCGACCTGACCCACCGCCTGCTGGCCTGCTCGCCTACCCGTGCCGGGGAGTTCGG
CGTGCCCTTGAGCGAGTTGCTGGGGCAATCCTTGTGGGGCTTTTGCACCGAGGAAATCGTGCGCAAGGAGAGGGCCCTCG
ACGATCTTGGCTGGCGCGAAGTGCTAGCGCCCCCGGCGCTGGAGTTCTTCAGCGGGCACAACGATTCGGCCATCGTGCCC
ATCGCGGCCAGCCAGTGCCGCTGGACCCGCCTGAACCTGTCCGACGGCAACGCGGTGCGGCTGGTGGAAACCCTCTGA
ATGTCCGCATCCTTGTTCACTTCCCCGCACCTGGGCCTGGCCCTGCGCCGCTGGCGCCTGCTGCACCGGGTCAAGCAACA
GCACGCCGCCGAGCTGTTCGGGGTGGCGCAGTCGAGCATTTCCCGCTGGGAAAACGGCCAGCAAGCCATGGAACCCAGCG
AGCGCGCCAAGCTGGAGCAACTGCTGGCGGCCAACCTCAGCGCCGCCGCCGACCAGGCCCTGGCCCGGTTGGTGAACGAC
AGCCCGCGGGCGGTGCACCTGGTCTGCGACCTGACCCACCGCCTGCTGGCCTGCTCGCCTACCCGTGCCGGGGAGTTCGG
CGTGCCCTTGAGCGAGTTGCTGGGGCAATCCTTGTGGGGCTTTTGCACCGAGGAAATCGTGCGCAAGGAGAGGGCCCTCG
ACGATCTTGGCTGGCGCGAAGTGCTAGCGCCCCCGGCGCTGGAGTTCTTCAGCGGGCACAACGATTCGGCCATCGTGCCC
ATCGCGGCCAGCCAGTGCCGCTGGACCCGCCTGAACCTGTCCGACGGCAACGCGGTGCGGCTGGTGGAAACCCTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|