Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 711492..711989 Replicon chromosome
Accession NZ_CP027705
Organism Pseudomonas sp. CMR5c

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C4K40_RS03220 Protein ID WP_083456916.1
Coordinates 711786..711989 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C4K40_RS03215 Protein ID WP_022642042.1
Coordinates 711492..711782 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K40_RS03195 707775..709892 - 2118 WP_053132271.1 TonB-dependent copper receptor -
C4K40_RS03200 709981..710373 - 393 WP_031320787.1 DUF2946 domain-containing protein -
C4K40_RS03205 710450..710929 - 480 WP_172681645.1 copper chaperone PCu(A)C -
C4K40_RS03210 710994..711392 - 399 WP_053132267.1 DUF2946 domain-containing protein -
C4K40_RS03215 711492..711782 - 291 WP_022642042.1 putative addiction module antidote protein Antitoxin
C4K40_RS03220 711786..711989 - 204 WP_083456916.1 hypothetical protein Toxin
C4K40_RS03230 712426..713154 - 729 WP_053132265.1 cobalt-precorrin-6A reductase -
C4K40_RS03235 713151..714248 - 1098 WP_053132262.1 cobalt-precorrin-5B (C(1))-methyltransferase -
C4K40_RS03240 714241..715485 - 1245 WP_053132259.1 bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cobalt-precorrin-6B (C(15))-methyltransferase -
C4K40_RS03245 715534..716937 + 1404 WP_083456915.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-64)

Antitoxin

Uncharacterized protein HI1420

(3-94)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 7683.78 Da        Isoelectric Point: 10.5328

>T99885 WP_083456916.1 NZ_CP027705:c711989-711786 [Pseudomonas sp. CMR5c]
MLGRFGDCVSIGGGVHEMRIHRGPGYRVYFSRRGERIYLLLIGGDKSPRSRDIQRARQLAHDLKNED

Download         Length: 204 bp

>T99885 NZ_CP027705:c711989-711786 [Pseudomonas sp. CMR5c]
CTGCTAGGGCGGTTCGGCGACTGTGTATCAATAGGAGGTGGAGTCCATGAGATGCGTATCCACCGCGGGCCCGGCTACCG
GGTGTACTTTTCACGGCGAGGCGAACGGATCTACCTGCTGTTGATCGGTGGTGACAAGAGCCCCCGGAGTCGCGACATCC
AACGAGCCCGGCAACTGGCTCACGACCTCAAGAACGAGGACTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10375.94 Da        Isoelectric Point: 6.2732

>AT99885 WP_022642042.1 NZ_CP027705:c711782-711492 [Pseudomonas sp. CMR5c]
MRTPVTRFDAADYLKTPQDMVAYLDACFEEDAGDGVLIRAALNDIARARGMTQVARDTGLGRESLYKALGSQGNPEFATI
IKVMKALGLKLQVSPA

Download         Length: 291 bp

>AT99885 NZ_CP027705:c711782-711492 [Pseudomonas sp. CMR5c]
ATGCGCACCCCAGTGACCCGCTTCGATGCGGCCGACTACCTCAAGACCCCGCAAGACATGGTGGCCTACCTCGATGCCTG
CTTCGAGGAAGATGCCGGTGATGGCGTGCTGATCCGCGCCGCCCTCAACGACATCGCCCGCGCCCGTGGCATGACCCAGG
TAGCCCGGGACACCGGCCTGGGCCGCGAAAGCCTGTACAAGGCGCTGGGCAGCCAGGGCAATCCCGAGTTCGCGACTATC
ATCAAGGTGATGAAGGCGCTGGGACTCAAGCTCCAGGTCAGCCCGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References